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Landos Biopharma, Inc. - LABP STOCK NEWS

Welcome to our dedicated page for Landos Biopharma news (Ticker: LABP), a resource for investors and traders seeking the latest updates and insights on Landos Biopharma stock.

Overview

Landos Biopharma, Inc. is a clinical-stage biopharmaceutical company dedicated to transforming the treatment paradigm for autoimmune diseases with innovative, oral therapeutic solutions. By focusing on immunometabolic modulation and novel approaches to inflammatory bowel disease (IBD), the company is at the forefront of addressing a critical gap in therapies for conditions like ulcerative colitis and Crohn’s disease.

Core Business and Research Focus

At its core, Landos is committed to developing first-in-class, oral therapies that offer improved safety and efficacy for patients with autoimmune conditions. The company’s primary research emphasis is on immunometabolic pathways that influence inflammatory responses. Its lead investigational asset, NX-13, is designed as a unique NLRX1 agonist with a bimodal mechanism of action, which not only exerts anti-inflammatory effects but also promotes epithelial repair. This dual mechanism is fundamental in presenting a treatment option that prioritizes patient convenience and reduced disruption to daily life.

Clinical Development and Innovation

Landos progresses its product pipeline through rigorous clinical testing. The ongoing clinical studies, especially the NEXUS Phase 2 trial evaluating NX-13 in patients with moderate to severe ulcerative colitis, highlight the company’s commitment to advancing clinical evidence in the field. By deploying a first-in-class approach, Landos is not only challenging the status quo of conventional therapies but also pioneering innovative research in immunometabolic modulation. The meticulous design of its trials and the focus on novel mechanisms ensure that the research is both comprehensive and targeted at addressing long-standing therapeutic gaps.

Market Position and Industry Significance

Within the competitive landscape of biopharmaceutical research, Landos Biopharma stands out due to its focused approach on oral immunotherapies and its strategic targeting of autoimmune diseases. The company’s research is driven by the clear need for improved treatment options that move beyond traditional, often suboptimal, therapies. By leveraging advanced clinical studies and novel scientific insights, Landos is well-positioned to inform and influence the future standard of care in the treatment of autoimmune disorders. Its integration into the larger ecosystem, as evidenced by strategic corporate developments, reinforces its capacity to contribute to industry innovation.

Scientific and Clinical Expertise

Landos’ commitment to developing therapies that address complex immunological processes is reflected in its precise targeting of pathways involved in immunometabolic regulation. The scientific community recognizes the significance of modulating NLRX1, which plays a critical role in both inflammatory responses and cellular repair mechanisms. By clearly articulating the biochemical basis behind its therapies, Landos demonstrates a deep expertise that is crucial in the competitive field of biotechnology.

Operational and Strategic Considerations

The company’s operational strategy is built around a rigorous clinical development process, complemented by its emphasis on quality and safety in clinical trials. Landos addresses several challenges inherent in drug development, from trial design and patient recruitment to managing regulatory expectations. This systematic approach not only underscores its commitment to scientific excellence but also reinforces its credibility in the competitive biopharmaceutical sector. Clear communication regarding its research methodology, technological focus, and strategic positioning adds to the trustworthiness and authority of its overall profile.

Conclusion

In summary, Landos Biopharma is a focused, clinically oriented biopharmaceutical company crafting a new path in the treatment of autoimmune diseases. By harnessing the potential of advanced immunometabolic modulation and pioneering novel oral therapies, the company aims to offer safer, more effective treatment options for patients who have long been underserved by existing therapies. The robust clinical development framework and scientific expertise embedded in its research reflect a well-considered approach to transforming patient care in the realm of autoimmune disorders.

Rhea-AI Summary

AbbVie has completed its acquisition of Landos Biopharma, enhancing its portfolio with NX-13, a first-in-class oral NLRX1 agonist currently in Phase 2 trials for treating ulcerative colitis (UC) and Crohn's disease (CD). The acquisition, priced at $20.42 per share plus up to $11.14 per share upon achieving a clinical milestone, aims to offer a novel, dual-action treatment approach to inflammatory bowel disease (IBD), combining anti-inflammatory properties and epithelial repair. Landos' stock will stop trading on NASDAQ from May 24, 2024. AbbVie expressed its commitment to transforming the standard of care for IBD patients.

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AbbVie Inc. (NYSE: ABBV) to acquire Landos Biopharma, Inc. (NASDAQ: LABP) for a total of $212.5 million to advance the development of NX-13, a first-in-class, oral NLRX1 agonist for the treatment of ulcerative colitis. The acquisition aims to fill a therapeutic gap in autoimmune diseases, with AbbVie recognizing the potential of NX-13 in addressing the needs of patients with ulcerative colitis and Crohn’s disease.
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Landos Biopharma, Inc. (LABP) reports financial results for Q4 2023, with sufficient cash to fund operations until mid-2025. The company is focused on developing novel oral medicines for autoimmune diseases, particularly the NX-13 clinical program for ulcerative colitis.
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Landos Biopharma, a clinical-stage biopharmaceutical company (NASDAQ: LABP), announced that six abstracts were accepted for poster presentation at the 19th Annual Congress of the European Crohn’s and Colitis Organisation (ECCO). The abstracts highlight new and additional data on immunometabolism modulation by activating NLRX1 and PLXDC2 with novel agonists such as NX-13 and LABP-69. The company has two novel targets anchoring libraries of immunometabolic modulation pathways, including four potentially first-in-class, once-daily, oral therapies targeting eight indications, including the clinical stage program NX-13 for ulcerative colitis (UC). NX-13 is currently in a Phase 2 proof-of-concept trial (NEXUS: NCT05785715) to evaluate the safety, efficacy and pharmacokinetics in patients with moderate to severe UC. The Company expects to report topline results in the fourth quarter of 2024.
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Landos Biopharma, Inc. (LABP) announced promising results for the NX-13 Phase 1b trial in patients with ulcerative colitis (UC). The drug demonstrated early signs of rapid symptomatic relief and endoscopic improvement, with top-line readout for the ongoing NEXUS Phase 2 trial expected in Q4 2024.
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Landos Biopharma, Inc. (NASDAQ: LABP) remains on track with the NEXUS Phase 2 Clinical Trial of NX-13 for Ulcerative Colitis, with top-line results planned for Q4 2024. The company also announced sufficient cash to fund operations into the first half of 2025.
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Landos Biopharma to present additional findings from Phase 1b study of NX-13 for ulcerative colitis at ACG 2023 Annual Scientific Meeting
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Landos Biopharma presents new data on NX-13 in Phase 1b study for Ulcerative Colitis at UEG Week 2023 congress
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Landos Biopharma collaborates with KU Leuven and University Hospitals Leuven to investigate effects of NX-13 on epithelial cells in ulcerative colitis patients. NEXUS Phase 2 trial on track for Q4 2024 results.
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FAQ

What is the current stock price of Landos Biopharma (LABP)?

The current stock price of Landos Biopharma (LABP) is $22.93 as of February 7, 2025.

What is the market cap of Landos Biopharma (LABP)?

The market cap of Landos Biopharma (LABP) is approximately 71.7M.

What is the core focus of Landos Biopharma?

Landos Biopharma focuses on developing novel, first-in-class, oral therapeutics specifically targeted at autoimmune diseases such as ulcerative colitis and Crohn's disease.

How does Landos address the unmet needs in autoimmune treatments?

The company aims to fill treatment gaps by advancing therapies that are safer, more effective, and less disruptive, prioritizing innovative immunometabolic modulation over conventional treatment approaches.

What is NX-13 and what makes it unique?

NX-13 is Landos' lead investigational asset; it is a first-in-class, oral NLRX1 agonist that employs a bimodal mechanism of action, providing both anti-inflammatory effects and promoting epithelial repair.

In which stage of development is Landos' lead asset currently?

NX-13 is in the clinical stage and is being evaluated in a Phase 2 proof-of-concept trial, which is designed to assess its efficacy and safety in patients with moderate to severe ulcerative colitis.

How does Landos differentiate itself in the competitive biopharmaceutical sector?

Landos differentiates itself by focusing on oral therapies that leverage immunometabolic modulation, addressing unmet clinical needs through innovative trial designs and a clear focus on patient quality of life.

What are the primary therapeutic areas targeted by Landos?

Landos primarily targets autoimmune diseases, with a specific focus on inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease through novel oral treatment strategies.

How does Landos ensure the scientific rigor of its clinical trials?

The company implements a robust clinical development process that emphasizes precision, safety, and clear evaluation of its novel mechanisms, ensuring that trial designs are in line with advanced scientific standards.

What role does immunometabolic modulation play in Landos' approach?

Immunometabolic modulation is central to Landos' strategy as it underpins the dual therapeutic action of their lead asset, influencing both inflammation reduction and tissue repair, which are critical for effective autoimmune disease treatment.
Landos Biopharma, Inc.

NYSE:LABP

LABP Rankings

LABP Stock Data

71.68M
1.33M
9.89%
52.04%
0.05%
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