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Kezar Life Sciences, Inc. - KZR STOCK NEWS

Welcome to our dedicated page for Kezar Life Sciences news (Ticker: KZR), a resource for investors and traders seeking the latest updates and insights on Kezar Life Sciences stock.

Kezar Life Sciences, Inc. (Nasdaq: KZR) is a clinical-stage biotechnology company dedicated to discovering and developing novel small molecule therapeutics to address unmet medical needs in autoimmunity and cancer. Founded in 2015 and headquartered in South San Francisco, California, Kezar focuses on creating therapies that can significantly improve patient outcomes.

The company's lead product candidate, Zetomipzomib (KZR-616), is a selective immunoproteasome inhibitor currently under clinical investigation. Zetomipzomib is being tested in Phase 2 trials for five autoimmune diseases, including lupus nephritis, autoimmune hemolytic anemia, immune thrombocytopenia, dermatomyositis, and polymyositis. In addition, Phase 1b/2 trials are underway for systemic lupus erythematosus and lupus nephritis, making it a promising candidate for treating multiple chronic immune-mediated diseases.

Kezar's preclinical pipeline also includes another selective immunoproteasome inhibitor, tentatively named KZR-TBD, aimed at treating oncology and autoimmune conditions. These efforts highlight Kezar's commitment to exploring innovative solutions for complex diseases.

Recently, Kezar Life Sciences has achieved significant milestones. Notably, in collaboration with Everest Medicines, the company received approval from China's National Medical Products Administration (NMPA) for the investigational new drug (IND) application for the Phase 2b PALIZADE trial of zetomipzomib in patients with lupus nephritis. This global, placebo-controlled trial will evaluate the efficacy and safety of zetomipzomib, marking Kezar's expansion into the Asian market.

Financially, Kezar Life Sciences continues to secure partnerships and funding to support its ambitious research and development goals. The company's strategic collaborations, like the one with Everest Medicines, enhance its ability to reach more patients and broaden its geographical footprint.

For more information, visit the company's official website at www.kezarlifesciences.com.

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Kezar Life Sciences reports financial results for Q1 2023 and provides a business update. PALIZADE Phase 2b trial for zetomipzomib in lupus nephritis on track to initiate in H1 2023. KZR-261 dose escalation study progressing, dose expansion study expected in H2 2023. Cash and marketable securities totaled $257.7 million as of March 31, 2023.
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Kezar Life Sciences, a clinical-stage biotechnology company (NASDAQ: KZR), announced the grant of nonqualified stock options to six employees, totaling 232,000 shares at an exercise price of $3.05 per share. This price corresponds to the closing price on April 3, 2023, the grant date. The options, part of an inducement award, will vest over four years, with 25% vesting on the first anniversary of the employee’s start date and the remaining shares vesting monthly. This award complies with Nasdaq Listing Rule 5635(c)(4). Kezar is focused on developing breakthrough treatments for immune-mediated and oncologic disorders, including its lead asset, Zetomipzomib, which has completed a Phase 2 trial for lupus nephritis and KZR-261, a candidate in an ongoing Phase 1 trial for solid tumors.

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Kezar Life Sciences reported a net loss of $68.2 million for 2022, compared to $54.6 million in 2021, and a Q4 net loss of $18.2 million. Cash and equivalents stood at $276.6 million as of December 31, 2022, up from $208.4 million in 2021. The company is advancing its zotomipzomib program with the initiation of the PALIZADE Phase 2b trial in lupus nephritis and the PORTOLA trial in autoimmune hepatitis, both set to begin in 2023. Additionally, the KZR-261 Phase 1 trial is currently enrolling its sixth cohort. The increase in research and development expenses reflects investments in these clinical programs, with total R&D costs rising to $51 million in 2022.

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Kezar Life Sciences, Inc. (NASDAQ: KZR) has announced the rescheduling of its virtual Research and Development Day to March 15, 2023, at 4:30 PM ET. The event aims to set expectations for 2023 and provide updates on its clinical assets, particularly the advancement of the PALIZADE study for zetomipzomib in lupus nephritis. Additionally, Dr. Craig S. Lammert will discuss autoimmune hepatitis, emphasizing the unmet treatment needs. Following the presentation, a Q&A session will be held. Zetomipzomib is noted for its potential in treating autoimmune disorders without causing immunosuppression.

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Kezar Life Sciences (Nasdaq: KZR) has announced a virtual Research and Development Day on March 22, 2023, at 4:30 PM ET. The event will detail the company's pipeline, focusing on zetomipzomib and its development in lupus nephritis, as well as the recently initiated PORTOLA study for autoimmune hepatitis. Key presentations will include insights from experts, such as Craig S. Lammert, M.D. Zetomipzomib, primarily aimed at autoimmune diseases, demonstrated favorable safety in trials. The event will also discuss KZR-261, a novel cancer treatment targeting the protein secretion pathway. Interested parties can register through Kezar's website.

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Kezar Life Sciences, a clinical-stage biopharmaceutical company, announced the grant of nonqualified stock options to three employees to purchase a total of 33,000 shares at an exercise price of $5.43 per share, equivalent to the closing price on March 2, 2023. The options will vest over four years, with 25% vesting after the first year and the remainder vesting monthly. This grant is part of the company's 2022 Inducement Plan and aims to attract new talent. Kezar is known for its innovative treatments for immune-mediated and oncologic disorders, including its lead asset, Zetomipzomib, currently in Phase 2 trials.

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Kezar Life Sciences, a clinical-stage biotechnology firm focused on immune-mediated and oncologic disorders, announced that Dr. Noreen Roth Henig will participate in a panel discussion on Autoimmune/Complement/Inflammation at the Cowen 43rd Annual Health Care Conference in Boston, MA, on March 7, 2023, at 10:30 am ET. A live webcast will be available on the company's website, with an archived version accessible for 90 days post-event. Kezar is advancing novel therapies, such as Zetomipzomib for lupus nephritis and KZR-261 for solid tumors, highlighting its commitment to innovative treatments.

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Kezar Life Sciences, a clinical-stage biotechnology firm, announced the grant of nonqualified stock options to five employees for the purchase of 131,000 shares at an exercise price of $7.10 per share. This price matches the closing value on February 3, 2023, the date of the grant. The stock options are part of an inducement award linked to employment and will vest over four years, with initial vesting occurring one year after the employee's start date. Kezar is advancing treatments for immune-mediated and oncologic disorders, including drug candidates like Zetomipzomib and KZR-261.

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Kezar Life Sciences, a clinical-stage biotechnology company, announced the granting of nonqualified stock options to two employees for purchasing 65,000 shares at an exercise price of $6.84 per share, equivalent to the closing price on January 6, 2023. The options will vest over four years, with 25% vesting on the first anniversary and the remainder vesting monthly thereafter. This grant is part of Kezar’s 2022 Inducement Plan and complies with Nasdaq Listing Rule 5635(c)(4). Kezar is focused on developing breakthrough treatments for immune-mediated and oncologic disorders, including its lead asset, Zetomipzomib, used in clinical trials.

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FAQ

What is the current stock price of Kezar Life Sciences (KZR)?

The current stock price of Kezar Life Sciences (KZR) is $6.38 as of December 20, 2024.

What is the market cap of Kezar Life Sciences (KZR)?

The market cap of Kezar Life Sciences (KZR) is approximately 47.2M.

What is Kezar Life Sciences focused on?

Kezar Life Sciences focuses on discovering and developing novel small molecule therapeutics to address unmet needs in autoimmunity and cancer.

What is Zetomipzomib (KZR-616)?

Zetomipzomib (KZR-616) is a selective immunoproteasome inhibitor in clinical trials for various autoimmune diseases, including lupus nephritis and systemic lupus erythematosus.

What clinical trials are currently underway for Zetomipzomib?

Zetomipzomib is in Phase 2 trials for five autoimmune conditions and Phase 1b/2 trials for systemic lupus erythematosus and lupus nephritis.

Where is Kezar Life Sciences headquartered?

Kezar Life Sciences is headquartered in South San Francisco, California.

What significant recent achievements has Kezar Life Sciences made?

Kezar recently received approval for its IND application for the Phase 2b PALIZADE trial in China, in partnership with Everest Medicines.

What are Kezar's preclinical products?

Kezar's preclinical products include KZR-TBD, a selective immunoproteasome inhibitor for treating autoimmune diseases and cancer.

When was Kezar Life Sciences founded?

Kezar Life Sciences was founded in 2015.

Who is Kezar Life Sciences' regional partner in Asia?

Kezar's regional partner in Asia is Everest Medicines, which helps conduct the Phase 2b PALIZADE trial for zetomipzomib.

How can I get more information about Kezar Life Sciences?

For more information, you can visit Kezar Life Sciences' official website at www.kezarlifesciences.com.

What is the PALIZADE trial?

The PALIZADE trial is a global, placebo-controlled Phase 2b clinical trial evaluating the efficacy and safety of zetomipzomib in patients with active lupus nephritis.

Kezar Life Sciences, Inc.

Nasdaq:KZR

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47.21M
6.02M
14.8%
63.9%
2.44%
Biotechnology
Pharmaceutical Preparations
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United States of America
SOUTH SAN FRANCISCO