Welcome to our dedicated page for Kazia Therapeuti news (Ticker: KZIA), a resource for investors and traders seeking the latest updates and insights on Kazia Therapeuti stock.
Kazia Therapeutics Limited (NASDAQ: KZIA) is an oncology-focused drug development and clinical-stage biotechnology company based in Sydney, Australia. News about Kazia typically centers on the progress of its investigational cancer therapies, particularly its lead program paxalisib, as well as pipeline additions such as EVT801 and a first-in-class PD-L1 protein degrader program.
Company announcements frequently highlight clinical and translational data for paxalisib, a brain-penetrant inhibitor of the PI3K / Akt / mTOR pathway. Recent news has included results from glioblastoma studies, early efficacy and biomarker findings in advanced triple-negative breast cancer and HER2-positive metastatic breast cancer, and mechanistic data showing reductions in circulating tumor cells and clusters, changes in tumor cell phenotypes, and reinvigoration of immune cell function.
Kazia’s news flow also covers regulatory and development strategy updates, such as its intention to request FDA Type C meetings to discuss overall survival data in newly diagnosed glioblastoma and potential regulatory pathways, as well as participation in initiatives like an Australian Medical Research Future Fund project using AI-enabled platforms to guide therapy sequencing in diffuse midline glioma and diffuse intrinsic pontine glioma.
Investors following KZIA news will also find information on capital markets activities, including private placements of equity securities, at-the-market offerings of American Depositary Shares, and Nasdaq listing compliance developments. Updates on the EVT801 VEGFR3 inhibitor program, the NDL2 PD-L1 degrader collaboration with QIMR Berghofer, and participation in major oncology conferences provide additional context on Kazia’s evolving pipeline and scientific positioning.
This news page aggregates these disclosures so readers can track key milestones in Kazia’s clinical programs, regulatory interactions, collaborations, and financing events over time.
Kazia Therapeutics is focusing on childhood brain cancer, leveraging its experience from adult brain cancer treatments. The company is addressing significant challenges in enrolling patients for clinical trials, creating a gap in treatment options. Despite limited data, Kazia is positioned to pioneer this niche market. Their current net present value is estimated at US$294m (US$22.28 per basic ADR). As of December 2021, Kazia reported net cash of US$11.0m and anticipates needing approximately US$51m in additional financing to support operations through 2024.
Kazia Therapeutics Limited (NASDAQ: KZIA; ASX: KZA) announced that CEO Dr. James Garner will present at two investor conferences. The first is the HC Wainwright Global Investment Conference in Miami, FL, from May 23-26, 2022, where he will discuss upcoming news from Kazia's clinical programs. The second is the LD Micro Invitational XII in Westlake Village, CA, from June 7-9, 2022, focusing on the company's licensing strategy and progress on paxalisib, its lead program targeting glioblastoma. Institutional investors can register for one-on-one meetings.
Kazia Therapeutics Limited (NASDAQ: KZIA) acknowledges 'DIPG Awareness Day' on May 17, 2022, highlighting the urgent need for increased awareness and research funding for childhood brain cancer, especially diffuse intrinsic pontine glioma (DIPG). This type of cancer has no FDA-approved treatment and a median survival of 9-11 months. Kazia's investigational drug, paxalisib, is under a phase II study for DIPG, with data expected in 2023. New preclinical data will be presented at the ISPNO Conference in June 2022, emphasizing the potential of paxalisib in offering hope to affected families.
Kazia Therapeutics Limited (NASDAQ: KZIA) announced the final data from its phase II study of paxalisib for newly diagnosed glioblastoma will be presented at the ASCO Annual Meeting from June 3-7, 2022, in Chicago, IL. The poster titled 'Paxalisib in patients with newly diagnosed glioblastoma' will take place on June 5, 2022. Abstracts will be released on May 26, 2022. Kazia specializes in oncology and is advancing paxalisib, recognized for its efficacy against brain tumors, alongside other therapies like EVT801.
Kazia Therapeutics Limited (NASDAQ: KZIA) announced promising preclinical data on paxalisib, showcased in three abstracts at the AACR Annual Meeting. The findings highlight paxalisib's efficacy in treating childhood brain cancers, particularly atypical teratoid/rhabdoid tumors (AT/RT) and diffuse intrinsic pontine glioma (DIPG), both of which lack FDA-approved therapies. Notably, paxalisib demonstrated survival benefits when combined with other cancer treatments. The ongoing phase II clinical trial in DIPG furthers its potential. Kazia aims to explore wider applications for paxalisib in pediatric brain cancers.
Kazia Therapeutics Limited (NASDAQ: KZIA; ASX: KZA) announced two poster presentations at the AACR Annual Meeting in New Orleans, detailing the phase I study of EVT801, a VEGFR3 inhibitor targeting advanced cancer. The study aims to assess safety, tolerability, and pharmacokinetics while employing innovative biomarker strategies to identify effective patient profiles. EVT801 is a promising candidate licensed from Evotec and commenced patient recruitment in November 2021, with initial data expected in the second half of 2022.
Kazia Therapeutics announces progress in its pivotal GBM AGILE study for lead asset paxalisib, with data expected in CY23. Recent US C-suite appointments indicate a focus on commercialization. The second asset, EVT801, is in human trials, with the first patient enrolled in France. The company's valuation has increased to US$294m or US$22.28 per basic ADR, driven by NPV roll-forward, despite lower cash and higher R&D costs. Net cash stood at US$11.0m as of December 31, 2021, indicating a runway into H123.
Kazia Therapeutics Limited (NASDAQ: KZIA; ASX: KZA) announced upcoming presentations at two key events. Scheduled for April 8-13, 2022, at the American Association of Cancer Research Annual Scientific Meeting in New Orleans, four abstracts related to their drug pipeline will be presented. This includes updates on EVT801 and paxalisib, both pivotal in treating advanced cancers. Additionally, CEO Dr. James Garner will discuss corporate progress at the 2022 Virtual Growth Conference from March 28-30, 2022. These presentations highlight Kazia's commitment to oncology research and drug development.
Kazia Therapeutics Limited (NASDAQ: KZIA) announces the initiation of a phase II clinical study of paxalisib combined with metformin and a ketogenic diet for treating glioblastoma at Weill Cornell Medicine. The trial will recruit 30-60 patients over two years, aiming to enhance treatment efficacy through a low-insulin state. Dr. Howard Fine will lead the trial, which is expected to yield significant data read-outs throughout 2022, including insights on progression-free survival. Kazia continues its commitment to advancing glioblastoma treatment, with multiple ongoing studies.
Kazia Therapeutics Limited (NASDAQ: KZIA) will present at the BIO CEO Conference in New York from February 14-17, 2022. CEO Dr. James Garner will deliver an update on the company's clinical-stage oncology programs, including paxalisib, a treatment for glioblastoma, and EVT801, a small-molecule inhibitor targeting various tumor types. The conference, hosted by the Biotechnology Innovation Organization, connects biotech companies with investors and analysts. Attendees can register via the conference website.
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