Welcome to our dedicated page for Kymera Therapeutics news (Ticker: KYMR), a resource for investors and traders seeking the latest updates and insights on Kymera Therapeutics stock.
Kymera Therapeutics, Inc. (NASDAQ: KYMR) is a biotechnology company harnessing the power of targeted protein degradation (TPD) to develop transformative treatments for previously untreatable diseases. Founded in 2016, and headquartered in Watertown, Massachusetts, Kymera is at the forefront of biotechnology, utilizing the body's innate protein recycling machinery to degrade disease-causing proteins rather than merely inhibiting them.
The company's pioneering platform, Pegasus™, leverages proprietary predictive modeling and an integrated degradation approach to address disease targets previously deemed intractable. This novel modality allows Kymera to target and degrade proteins involved in various critical pathways, including those in immunological diseases and oncology. Key drugs in their pipeline include:
- KT-474: An IRAK4 degrader currently in Phase 2 trials for immuno-inflammatory conditions.
- KT-333: A STAT3 degrader in Phase 1 trials, targeting hematological malignancies and solid tumors.
- KT-253: An MDM2 degrader undergoing Phase 1 trials, aimed at cancers with p53 pathway involvement.
- KT-621: A STAT6 degrader poised to enter Phase 1 trials, showing promising preclinical results for treating TH2-driven diseases like asthma and atopic dermatitis.
Kymera's achievements include successful partnerships with leading pharmaceutical companies such as Sanofi, ongoing collaborations with research institutions, and securing significant financial backing with over $745 million in cash reserves to support operations into 2027. The company's innovative approach and robust pipeline have earned it recognition as one of Boston’s top workplaces.
Kymera continues to make significant strides in drug discovery and development, with a focus on delivering highly effective, convenient oral therapies. Recent updates include positive preclinical and clinical data presentations at major medical conferences, highlighting the potential of their degradation technology to revolutionize treatment paradigms across various diseases.
For more information, visit Kymera Therapeutics or follow them on X (formerly Twitter) and LinkedIn.
Kymera Therapeutics (NASDAQ: KYMR) will participate in a virtual fireside chat at the Goldman Sachs 42nd Annual Global Healthcare Conference on June 9 at 4:40 p.m. ET. The event will be available for live streaming on Kymera's website, with a replay accessible for one month afterward. Kymera is a biopharmaceutical company focused on targeted protein degradation, aiming to develop innovative therapies for chronic diseases. Their proprietary platform enables the creation of small molecule degraders to tackle disease-causing proteins.
Kymera Therapeutics (NASDAQ: KYMR) presented new findings at the Ligase Targeting Drug Development Summit, revealing a novel E3 ligase with selective expression in healthy tissues and broad presence in cancer cells. The research highlights a proof-of-concept STAT3 degrader that demonstrated effective degradation in various cancer cell lines. Kymera's E3 Ligase Whole-Body Atlas has identified around 600 unique E3 ligases, facilitating targeted therapy development. The Pegasus™ platform aims to create tissue-selective degraders for more effective therapies, focusing on previously undrugged proteins.
Kymera Therapeutics (NASDAQ: KYMR) announced promising preclinical findings for KT-474, an oral IRAK4 degrader, showing its superior anti-inflammatory effects compared to existing IRAK4 kinase inhibitors. This late-breaking data, highlighted at the IMMUNOLOGY2021 conference, demonstrates KT-474's efficacy in various models of immune-inflammatory diseases, including atopic dermatitis and rheumatoid arthritis. With a broader mechanism targeting both kinase and scaffolding functions of IRAK4, KT-474 aims to address significant unmet medical needs. Further clinical validation is anticipated in upcoming trials.
Kymera Therapeutics (NASDAQ: KYMR) reported strong business highlights for Q1 2021, with collaboration revenues soaring to $18.7 million, up from $3.4 million in Q1 2020. The company initiated a Phase 1 trial for its oral IRAK4 degrader, KT-474, in February 2021, targeting immune-inflammatory diseases. Expected milestones include proof-of-biology data for KT-474 in 4Q 2021. Additionally, preclinical programs KT-413 and KT-333 are advancing towards clinical trials in 2H 2021. Despite a net loss of $13.1 million, Kymera has sufficient cash to fund operations into 2025.
Kymera Therapeutics (NASDAQ: KYMR) appointed Juliet Williams, PhD, as Senior Vice President, Head of Biology. Dr. Williams brings 20 years of experience in the biopharmaceutical sector, including drug discovery leadership roles at Novartis and Sanofi. Her expertise is expected to enhance Kymera's pipeline, including programs in immunology and oncology. This strategic hire is poised to bolster Kymera's efforts in developing targeted protein degradation therapies aimed at treating challenging diseases.
Kymera Therapeutics (NASDAQ: KYMR) has announced its participation in two upcoming investor conferences. The company will present at the BofA Securities 2021 Virtual Healthcare Conference on May 13 at 3:30 p.m. ET and at the UBS Global Healthcare Virtual Conference on May 25 at 12:00 p.m. ET. Live webcasts will be available on Kymera's website, with archived replays for 30 days. Kymera focuses on targeted protein degradation to address challenging disease targets using its Pegasus™ platform, aiming to develop new treatments for various immune-inflammatory diseases and cancers.
Kymera Therapeutics (NASDAQ: KYMR) announced new preclinical data for its IRAK4 degrader KT-474 at the IMMUNOLOGY2021™ annual meeting. The data show KT-474's superior anti-inflammatory activity over existing IRAK4 inhibitors in various models. The presentation will occur on May 13, 2021, highlighting its impact on conditions like atopic dermatitis and rheumatoid arthritis. The company initiated a Phase 1 trial in February to assess KT-474's safety and efficacy, indicating its potential as a first-in-class therapy.
Kymera Therapeutics (KYMR) presented positive data at the 2021 Society for Investigative Dermatology Annual Meeting regarding its IRAK4 degrader, KT-474. The non-interventional study involved 30 hidradenitis suppurativa (HS) patients, revealing significant IRAK4 protein overexpression in HS skin lesions compared to healthy subjects. KT-474 demonstrated the ability to inhibit inflammatory gene upregulation in treated monocytes. The findings support KT-474's potential therapeutic impact on HS, a chronic inflammatory disease with unmet medical needs. Future data is anticipated from ongoing studies.
Kymera Therapeutics (NASDAQ: KYMR) has been recognized by the Boston Business Journal as one of the 2021 Best Places to Work in Massachusetts. This accolade reflects the company’s commitment to fostering a positive work culture focused on transparency, inclusion, and innovation. Kymera aims to advance targeted protein degradation therapies to address challenging disease targets. Their platform, Pegasus™, focuses on degrading disease-causing proteins, targeting previously inaccessible pathways. The recognition underscores Kymera's ambition to enhance its organizational capabilities as it progresses in the biopharmaceutical sector.
Kymera Therapeutics (NASDAQ: KYMR) recently unveiled preclinical data demonstrating the effectiveness of KT-413, a dual-action IRAKIMiD degrader. In MYD88-mutant diffuse large B cell lymphoma (DLBCL) models, KT-413 achieved superior tumor regression compared to existing therapies, such as IMiDs and selective IRAK4 targeting. The company plans to submit an Investigational New Drug Application (IND) and initiate a Phase 1 trial in the latter half of 2021, focusing on relapsed/refractory B cell lymphomas, particularly MYD88-mutant DLBCL, which represents a significant patient population.
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