Welcome to our dedicated page for Kura Oncology news (Ticker: KURA), a resource for investors and traders seeking the latest updates and insights on Kura Oncology stock.
Kura Oncology, Inc. (symbol: KURA) is a clinical-stage biopharmaceutical company based in San Diego, dedicated to pioneering precision medicines for cancer treatment. Leveraging advances in cancer genomics, Kura develops targeted therapies and companion diagnostics designed to address the genetic underpinnings of various cancers, optimizing treatment efficacy and safety.
The company's flagship product candidate, Tipifarnib, is under investigation for treating both solid tumors and blood cancers. Tipifarnib is a potent farnesyl transferase inhibitor, currently undergoing Phase 1/2 trials in combination with alpelisib for patients with head and neck squamous cell carcinoma.
Another key candidate, Ziftomenib, targets acute myeloid leukemia (AML) with NPM1 and KMT2A mutations. Highlighted by its recent Breakthrough Therapy Designation from the FDA, Ziftomenib is involved in multiple clinical trials, including the KOMET-001 and KOMET-007 studies. Early results show promising efficacy and a favorable safety profile, particularly in the combination with current standards of care like venetoclax and azacitidine.
Kura is also advancing KO-2806, a next-generation farnesyl transferase inhibitor, in a Phase 1 dose-escalation trial as a monotherapy and in combination with other targeted therapies for renal and lung cancers.
Financially, Kura remains robust, with cash reserves projected to support operations through 2027. The company has an ongoing commitment to aggressive research, development, and pre-commercial activities, ensuring continued progression of its promising pipeline.
The company's recent achievements include reporting preliminary clinical data from the KOMET-007 trial and securing additional financing to reinforce its financial position. Kura continues its mission to bring life-saving therapies to patients with high unmet medical needs, aiming to improve and extend the lives of those battling cancer.
Kura Oncology, Inc. (Nasdaq: KURA) announced promising preclinical data showing the potential of farnesyl transferase inhibitors (FTIs) to treat solid tumors. These findings were presented at the AACR Annual Meeting, highlighting the synergistic effects of tipifarnib combined with targeted therapies like KRASG12C inhibitors and TKIs. Kura plans to initiate the Phase 1 dose-escalation trial (FIT-001) of KO-2806, a next-generation FTI, later this year, focusing on its safety and effectiveness as a monotherapy and in combination therapies. The company aims for KO-2806 to address adaptive resistance mechanisms that limit the effectiveness of current targeted cancer therapies.
Kura Oncology (Nasdaq: KURA) announced the acceptance of two abstracts for presentation at the AACR Annual Meeting in Orlando, scheduled from April 14-19, 2023. The presentations will showcase preclinical data on combining farnesyl transferase inhibitors (FTIs) with KRASG12C inhibitors and tyrosine kinase inhibitors, which may help prevent resistance to targeted therapies. The company recently received FDA clearance for the Investigational New Drug application of KO-2806, a next-generation FTI, and plans to initiate the FIT-001 Phase 1 trial later this year.
SAN DIEGO, March 1, 2023 (GLOBE NEWSWIRE) -- Kura Oncology, a clinical-stage biopharmaceutical company focused on precision cancer medicines, announced that CEO Troy Wilson will participate in several investor conferences. Key events include:
- A “Leukemia Corporate Panel” at the Cowen Health Care Conference in Boston on March 8, 2023, at 12:50 p.m. ET.
- A fireside chat at the Cowen Health Care Conference on the same day at 2:50 p.m. ET.
- A fireside chat at the Barclays Global Healthcare Conference in Miami on March 14, 2023, at 2:35 p.m. ET.
Live webcasts will be available on Kura's website, with archived replays post-event.
Kura Oncology reported promising Phase 1 data for ziftomenib, showing a 30% complete response (CR) rate among 20 patients with NPM1-mutant AML. Ziftomenib is now in a registration-directed trial (KOMET-001) aiming for up to 85 patients. The company has cleared the IND for KO-2806, its next-generation farnesyl transferase inhibitor. Kura received a $25 million investment from Bristol Myers Squibb, boosting its cash reserves to $438 million, sufficient to fund operations into Q4 2025. The company plans multiple combination trials for ziftomenib, marking potential growth in precision cancer medicine.
Kura Oncology, Inc. (Nasdaq: KURA) will release its fourth quarter and full year 2022 financial results on February 23, 2023, after U.S. market close. A conference call and webcast will follow at 4:30 p.m. ET to discuss the results and provide corporate updates. Kura is focused on precision medicine for cancer, with ongoing trials for its drug candidates. Ziftomenib is in a registration-directed trial for NPM1-mutant acute myeloid leukemia, while Tipifarnib has received Breakthrough Therapy Designation in treating HRAS-mutant head and neck squamous cell carcinoma. To join the call, U.S. callers can dial 1-877-407-4018.
Kura Oncology (Nasdaq: KURA) announced the initiation of its KOMET-001 Phase 2 trial for ziftomenib, a novel menin inhibitor targeting NPM1-mutant relapsed or refractory acute myeloid leukemia (AML). This follows promising Phase 1 results, which showed a 30% complete response rate among 20 patients at the recommended dosage of 600 mg. The Phase 2 trial aims to enroll 85 patients across the U.S. and Europe, focusing on complete response and safety as primary endpoints. Ziftomenib has received Orphan Drug Designation from the FDA, underscoring its potential in addressing the high unmet needs of AML patients with NPM1 mutations.
Kura Oncology, a clinical-stage biopharmaceutical company focused on precision cancer therapies, announced its participation in the virtual SVB Securities Global Biopharma Conference. CEO Troy Wilson will engage in a fireside chat at 5:00 p.m. ET on February 14, 2023. A live audio webcast will be accessible on Kura's website, with an archived replay available thereafter. Kura's pipeline includes Ziftomenib for acute myeloid leukemia and Tipifarnib, which has received Breakthrough Therapy Designation for HRAS-mutant head and neck squamous cell carcinoma. Kura is also advancing KO-2806 through early clinical studies.
Kura Oncology (Nasdaq: KURA) announced that the FDA has cleared its Investigational New Drug (IND) application for KO-2806, a next-generation farnesyl transferase inhibitor (FTI) aimed at treating advanced solid tumors. The company plans to conduct a Phase 1 first-in-human study to assess the safety, tolerability, and preliminary antitumor activity of KO-2806, both as a monotherapy and in combination with other therapies. Kura aims to start this trial in Q3 2023, with KO-2806 designed to enhance the efficacy of earlier FTI candidates and address drug resistance in cancer treatments. The IND clearance is a pivotal step in expanding Kura's clinical pipeline.
Kura Oncology announced promising results from its KOMET-001 Phase 1/2 trial of ziftomenib for NPM1-mutant and KMT2A-rearranged acute myeloid leukemia (AML). The trial showed a 30% complete remission (CR) rate at a 600 mg dose among 20 NPM1-mutant patients, with a low 5% rate of Grade 3 differentiation syndrome. The FDA has recommended 600 mg as the Phase 2 dose. Kura plans to initiate a registration-directed trial in Q1 2023 and explore combination therapies. These results highlight ziftomenib's potential as a promising treatment in a patient population with significant unmet needs.
Kura Oncology has announced an investor event on December 10, 2022, at 11:15 a.m. CT, following an oral presentation of data from the KOMET-001 trial at the ASH Annual Meeting in New Orleans. This event will feature insights from Kura's management and investigators on ziftomenib, a selective menin inhibitor, currently in Phase 1/2 trials targeting acute myeloid leukemia. Attendees can register for the live webcast on Kura's website, with an archived replay available afterwards.
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