Welcome to our dedicated page for Keros Therapeutics news (Ticker: KROS), a resource for investors and traders seeking the latest updates and insights on Keros Therapeutics stock.
Keros Therapeutics, Inc. (Nasdaq: KROS) is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of novel treatments for patients suffering from hematological and musculoskeletal disorders. The company’s mission focuses on addressing high unmet medical needs through innovative therapeutic solutions.
At the forefront of Keros’ pipeline is KER-050, a protein therapeutic product candidate aimed at treating low blood cell counts, or cytopenias, including anemia and thrombocytopenia in patients with myelodysplastic syndromes (MDS) and myelofibrosis. KER-050 is currently in Phase 2 clinical trials, with promising data presented at the 65th American Society of Hematology meeting showcasing its potential to ameliorate ineffective hematopoiesis and improve patient outcomes.
Another key product in development is KER-012, a small molecule being developed for the treatment of pulmonary arterial hypertension (PAH) and cardiovascular disorders. This candidate is also in Phase 2 trials and has shown encouraging preliminary results, particularly in treating bone loss disorders such as osteoporosis and osteogenesis imperfecta.
KER-047, another small molecule candidate, targets anemia and the rare genetic disorder, fibrodysplasia ossificans progressiva (FOP). Currently in Phase 1 clinical trials, KER-047 aims to address significant gaps in treatment for these conditions.
Financially, Keros reported a net loss of $39.4 million for the third quarter of 2023, attributed to increased research and development efforts. Despite this, the company maintains a solid cash balance of $287.9 million as of September 30, 2023, expected to fund operations into the fourth quarter of 2025. The recent public offering of $120 million in common stock further strengthens their financial position.
Keros’ strategic partnerships and collaborations play a crucial role in its development strategy. The company’s agreement with Hansoh (Shanghai) Healthtech Co., Ltd. in 2021 for manufacturing technology transfer is a significant step towards commercial scalability.
The company’s commitment to advancing its pipeline and achieving clinical milestones is evident through its continuous updates and transparent communication with stakeholders. Upcoming milestones include updates on the KER-050 and KER-012 programs, reflecting Keros’ proactive approach in driving innovation and improving patient lives.
Keros Therapeutics remains a leader in leveraging the transforming growth factor-beta (TGF-β) family of proteins, aiming to provide meaningful and potentially disease-modifying benefits to patients.
Keros Therapeutics has initiated a Phase 2 clinical trial for KER-050, targeting anemia and thrombocytopenia in patients with myelodysplastic syndromes (MDS). The first two participants have been dosed, with initial data expected by mid-2021. This open-label trial aims to confirm KER-050's safety and tolerability in patients with varying risks of MDS. Results from prior Phase 1 trials showed a robust hematological response in healthy volunteers. KER-050 could potentially address the significant unmet medical needs in MDS, affecting up to 170,000 patients annually in the U.S.
Keros Therapeutics, Inc. (Nasdaq: KROS), a clinical-stage biopharmaceutical company, announced that CEO Jasbir S. Seehra, Ph.D., will present at the H.C. Wainwright 22nd Annual Global Investment Conference on September 14, 2020, at 10:30 am ET. Keros specializes in developing novel treatments for hematological and musculoskeletal disorders with high unmet needs. Its lead candidates include KER-050 for cytopenias, KER-047 for anemia and fibrodysplasia ossificans progressiva, and KER-012 for bone loss disorders and pulmonary arterial hypertension.
Keros Therapeutics, Inc. (Nasdaq: KROS) announced positive preclinical results for KER-012 during the ASBMR 2020 Annual Meeting. KER-012, an activin receptor type II ligand trap, significantly increased trabecular bone volume in mice by reducing catabolism and enhancing anabolism. Key findings showed an 82.0% rise in bone volume and significant increases in trabecular thickness and formation rates. KER-012 aims to address conditions like osteoporosis, with potential implications for treating cancer-induced bone loss. CEO Jasbir S. Seehra highlighted the unique mechanism of KER-012 as a significant advancement in bone health treatments.
Keros Therapeutics (KROS) reported its Q2 2020 financial results, highlighting a net loss of $10.8 million, an increase from $2.9 million in Q2 2019. The rise in losses was attributed to heightened research and development efforts, totaling $7.3 million, as well as increased general and administrative expenses amounting to $3.7 million. Keros closed its initial public offering, bringing its cash reserves to $144.7 million, projected to fund operations into 2022. The company plans to initiate multiple Phase 2 trials for its lead programs in 2021.
Keros Therapeutics announced the completion of cohorts in a Phase 1 clinical trial for its lead compound, KER-047, targeting anemias and fibrodysplasia ossificans progressiva. The trial showed target engagement and a reduction in hepcidin, indicating potential for effective iron mobilization. No serious adverse events occurred, with common side effects including headache and nausea. Keros plans to expand the trial further and expects to commence Phase 2 trials in early 2021. The study is conducted in collaboration with Mass General Brigham and NIH’s NCATS.
Keros Therapeutics (KROS), a clinical-stage biopharmaceutical firm, will be included in the Russell 2000® Index effective June 26, 2020. This index represents small-cap U.S. stocks and is utilized widely by institutional investors for benchmarking. Approximately $9 trillion in assets track Russell indexes. Keros specializes in innovative treatments for hematological and musculoskeletal disorders, with notable product candidates including KER-050, KER-047, and KER-012, targeting conditions like anemia and bone loss.
Keros Therapeutics (KROS) presented data from its Phase 1 clinical trial of KER-050 at the 25th Annual Congress of the European Hematology Association. The trial demonstrated that KER-050 was well-tolerated and elicited significant increases in key hematological parameters, including hemoglobin and platelets, in healthy post-menopausal women. Additionally, preclinical studies showed KER-050's potential to enhance hematopoiesis and offered insights into a novel ALK2 kinase inhibitor that could mitigate anemia in iron-refractory iron deficiency anemia (IRIDA) models. Keros plans to initiate Phase 2 trials for KER-050 in patients with myelodysplastic syndromes and myelofibrosis.
Keros Therapeutics, Inc. (Nasdaq: KROS) announced that President and CEO Jasbir S. Seehra, Ph.D., will present at the Jefferies Virtual Healthcare Conference on June 4, 2020, at 9:00 am ET. Keros is a clinical-stage biopharmaceutical company specializing in treatments for hematological and musculoskeletal disorders with significant unmet needs. Their lead candidates include KER-050 for cytopenias, KER-047 for anemia related to hepcidin, and KER-012 for bone loss disorders.
Keros Therapeutics, Inc. (KROS) reported Q1 2020 financial results and business updates. The company experienced a net loss of $11.9 million, up from $3.2 million in Q1 2019, attributed to R&D and public company transition costs. They completed a Series C financing raising $56 million in March and an IPO generating $110.4 million in April, providing a cash balance of $54.5 million as of March 31, 2020, expected to sustain operations into H2 2022. Progress continues with KER-047 and KER-050, and a Phase 2 trial for KER-050 is set for H2 2020, pending COVID-19 impacts.
Keros Therapeutics, Inc. (Nasdaq: KROS) has announced four abstracts showcasing data from its KER-050 and ALK2 hematology programs at the virtual 25th Annual Congress of the European Hematology Association (EHA) from June 11-14, 2020. Key presentations include details on KER-050's effects on hemoglobin and platelet increases, red blood cell production in cynomolgus monkeys, and its potential for treating ineffective erythropoiesis. The company plans to commence Phase 2 trials for KER-050 in patients with myelodysplastic syndromes and myelofibrosis later this year.
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