Keros Therapeutics to Present at the 27th Annual Congress of the European Hematology Association

Rhea-AI Summary

Keros Therapeutics, Inc. (Nasdaq: KROS) announced the presentation of three abstracts from its KER-050 and ALK2 hematology programs at the 27th Annual Congress of the European Hematology Association (EHA) from June 9-17, 2022. The abstracts include a Phase 2 study on KER-050 for anemia treatment in myelodysplastic syndromes, along with two preclinical studies related to platelet production and anemia of inflammation. KER-050 aims to address low blood cell counts in patients suffering from significant hematological disorders.

LEXINGTON, Mass., May 12, 2022 (GLOBE NEWSWIRE) -- Keros Therapeutics, Inc. (“Keros”) (Nasdaq: KROS), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel treatments for patients suffering from hematological and musculoskeletal disorders with high unmet medical need today announced that three abstracts will be presented from the KER-050 and ALK2 hematology programs at the 27th Annual Congress of the European Hematology Association (“EHA”), to be held both virtually and in person from June 9-17, 2022.

The following abstracts were posted to the EHA website on May 12, 2022, 10:00 a.m. Eastern time.

Clinical Presentation

“A Phase 2, open-label, ascending dose study of KER-050 for the treatment of anemia in patients with very low, low, or intermediate risk myelodysplastic syndromes”

• Abstract Code: P776
• Session Title: Poster session
• Session Date and Time: Friday, June 10, 2022 – 10:30 am to 11:45 am Eastern time
  

Preclinical Presentations

“RKER-050, a novel inhibitor of TGF-β superfamily signaling, induced platelet production in healthy mouse megakaryocytes”

• Abstract Code: P1410
• Session Title: Poster session
• Session Date and Time: Friday, June 10, 2022 – 10:30 am to 11:45 am Eastern time
  

“ALK2 inhibition lowered hepcidin and liberated spleen iron for erythropoiesis in anemia of inflammation”

• Abstract Code: P1567
• Session Title: Poster session
• Session Date and Time: Friday, June 10, 2022 – 10:30 am to 11:45 am Eastern time
  

About KER-050

Keros’ lead protein therapeutic product candidate, KER-050, is an engineered ligand trap comprised of a modified ligand-binding domain of the transforming growth factor-beta receptor known as activin receptor type IIA that is fused to the portion of the human antibody known as the Fc domain. KER-050 is being developed for the treatment of low blood cell counts, or cytopenias, including anemia and thrombocytopenia, in patients with myelodysplastic syndromes, or MDS, and in patients with myelofibrosis.

About Keros Therapeutics, Inc.

Keros is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel treatments for patients suffering from hematologic and musculoskeletal disorders with high unmet medical need. Keros is a leader in understanding the role of the transforming growth factor-beta family of proteins, which are master regulators of red blood cell and platelet production as well as of the growth, repair and maintenance of muscle and bone. Keros’ lead protein therapeutic product candidate, KER-050, is being developed for the treatment of low blood cell counts, or cytopenias, including anemia and thrombocytopenia, in patients with MDS and in patients with myelofibrosis. Keros’ lead small molecule product candidate, KER-047, is being developed for the treatment of anemia resulting from iron imbalance. Keros’ third product candidate, KER-012, is being developed for the treatment of pulmonary arterial hypertension and for the treatment of disorders associated with bone loss, such as osteoporosis and osteogenesis imperfecta.

Cautionary Note Regarding Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Words such as "anticipates," "believes," "expects," "intends," “plans,” “potential,” "projects,” “would” and "future" or similar expressions are intended to identify forward-looking statements. Examples of these forward-looking statements include statements concerning: Keros’ presentation plans for the upcoming EHA annual meeting. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. These risks and uncertainties include, among others: Keros’ limited operating history and historical losses; Keros’ ability to raise additional funding to complete the development and any commercialization of its product candidates; Keros’ dependence on the success of its lead product candidates, KER-050 and KER-047; that Keros may be delayed in initiating, enrolling or completing any clinical trials; competition from third parties that are developing products for similar uses; Keros’ ability to obtain, maintain and protect its intellectual property; Keros’ dependence on third parties in connection with manufacturing, clinical trials and pre-clinical studies; and risks relating to the impact on our business of the COVID-19 pandemic or similar public health crises.

These and other risks are described more fully in Keros’ filings with the Securities and Exchange Commission (“SEC”), including the “Risk Factors” section of the Company’s Quarterly Report on Form 10-Q, filed with the SEC on May 5, 2022, and its other documents subsequently filed with or furnished to the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Except to the extent required by law, Keros undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Investor Contact:

Justin Frantz
jfrantz@soleburytrout.com
617-221-9100

FAQ

What are the key abstracts presented by Keros Therapeutics at the EHA Congress 2022?

Keros Therapeutics presented three abstracts, including studies on KER-050 for anemia treatment and preclinical findings on platelet production and anemia of inflammation.

When will Keros Therapeutics present its abstracts at the EHA Congress?

Keros Therapeutics will present its abstracts on June 10, 2022, from 10:30 am to 11:45 am Eastern time.

What is KER-050 developed for?

KER-050 is developed to treat low blood cell counts, particularly anemia and thrombocytopenia, in patients with myelodysplastic syndromes.

What is the significance of the European Hematology Association Congress for Keros Therapeutics?

The EHA Congress is significant for Keros as it provides a platform to showcase their research advancements in hematology and connect with key stakeholders in the field.

What other product candidates does Keros Therapeutics have aside from KER-050?

Keros Therapeutics is also developing KER-047 for anemia resulting from iron imbalance and KER-012 for pulmonary arterial hypertension and bone loss disorders.