Welcome to our dedicated page for Kiniksa Pharmaceuticals International, plc news (Ticker: KNSA), a resource for investors and traders seeking the latest updates and insights on Kiniksa Pharmaceuticals International, plc stock.
Kiniksa Pharmaceuticals, Ltd. (Nasdaq: KNSA) is a commercial-stage biopharmaceutical company dedicated to discovering, acquiring, developing, and commercializing therapeutic medicines for patients with debilitating diseases that have significant unmet medical needs. Headquartered in Hamilton, Bermuda, Kiniksa is at the forefront of developing immune-modulating assets aimed at addressing a spectrum of cardiovascular and autoimmune conditions.
The company’s clinical-stage product candidates include:
- ARCALYST (rilonacept): The first and only FDA-approved therapy for recurrent pericarditis, a debilitating inflammatory cardiovascular disease. ARCALYST is also approved for cryopyrin-associated periodic syndromes (CAPS) and deficiency of IL-1 receptor antagonist (DIRA).
- Mavrilimumab: An investigational monoclonal antibody targeting the GM-CSF receptor, currently being evaluated for its potential in treating giant cell arteritis and other rare cardiovascular diseases.
- Vixarelimab: An investigational monoclonal antibody inhibitor of signaling through OSMRβ.
- Abiprubart (formerly KPL-404): A humanized monoclonal antibody designed to inhibit the CD40-CD154 interaction, aimed at treating autoimmune diseases such as rheumatoid arthritis and Sjogren’s Disease.
Kiniksa’s robust pipeline is supported by significant financial strength. The company reported strong revenue growth with ARCALYST, achieving net product revenue of approximately $233.1 million in 2023, a 90% year-over-year increase. This financial performance provides a solid foundation for future investments in both commercial and clinical development projects.
Recent news highlights Kiniksa’s progress:
- In July 2023, Kiniksa announced plans to raise its 2023 ARCALYST sales guidance to between $220 million and $230 million, citing increased prescriber adoption and patient enrollments.
- In October 2023, the company reported third-quarter financial results and the completion of enrollment in the third cohort of the Phase 2 trial of KPL-404 in rheumatoid arthritis, with data expected in the first quarter of 2024.
- In February 2024, Kiniksa announced its plans to initiate a Phase 2b trial of abiprubart in Sjogren’s Disease in the second half of 2024, supported by robust ARCALYST revenue growth and a strong cash position.
For more information about Kiniksa and its pipeline, visit www.kiniksa.com.
Kiniksa Pharmaceuticals reported Q1 2022 net revenue of $22.2 million from ARCALYST, contributing to total revenues of $32.2 million. The company anticipates full-year net revenue from ARCALYST between $115 million and $130 million and expects cash reserves to sustain operations through 2024. Kiniksa's strategic collaboration with Huadong Medicine is expected to yield potential milestone payments up to $640 million. Despite a net loss of $25.2 million, this is an improvement from the previous year's loss of $49.5 million.
Kiniksa Pharmaceuticals, Ltd. (KNSA) will hold a conference call on May 3, 2022, at 8:30 a.m. Eastern Time to discuss its Q1 2022 financial results and corporate activities. A live webcast will be available on their website, with a replay accessible 48 hours post-event. Kiniksa focuses on developing therapeutic medicines for debilitating diseases, with a portfolio that includes ARCALYST®, vixarelimab, KPL-404, and mavrilimumab, targeting significant unmet medical needs through innovative biologic mechanisms.
Kiniksa Pharmaceuticals reported Q4 2021 net revenue of $18.7 million from ARCALYST, totaling $38.5 million for the full year. Profitability was achieved in Q4 2021. The company expects ARCALYST net revenue for 2022 to range from $115 million to $130 million. A strategic collaboration with Huadong Medicine is set to enhance the development of ARCALYST and mavrilimumab in the Asia Pacific. Kiniksa's Q4 2021 net loss narrowed to $36.3 million from $53.7 million year-over-year, while cash reserves stood at $182.2 million.
Kiniksa Pharmaceuticals (KNSA) announces a strategic collaboration with Huadong Medicine to develop and commercialize ARCALYST and mavrilimumab in the Asia Pacific region, excluding Japan. Kiniksa will receive $22 million upfront and could earn up to $640 million in milestone payments, alongside tiered royalties. This partnership aims to enhance access to treatments for severe autoimmune diseases, leveraging Huadong's regional expertise and resources.
Kiniksa Pharmaceuticals, Ltd. (Nasdaq: KNSA) will hold a conference call and live webcast on February 22, 2022, at 8:30 a.m. ET to discuss its fourth quarter and full-year 2021 financial results and provide a corporate update. The event aims to inform investors and the public about the company's performance and strategies. A live webcast will be available on its website, with a replay accessible within 48 hours. Kiniksa focuses on developing therapeutic medicines for diseases with significant unmet needs, utilizing innovative assets like ARCALYST and mavrilimumab.
Kiniksa Pharmaceuticals (KNSA) provided a corporate update on January 10, 2022, highlighting significant milestones for 2022. The company noted a successful launch of ARCALYST for recurrent pericarditis, with strong adoption. Year-end cash reserves are approximately $182 million, enough to fund operations into 2024. Upcoming developments include Phase 2b data for vixarelimab in prurigo nodularis expected in 2H 2022 and KPL-404's Phase 2 trial in rheumatoid arthritis currently enrolling patients. The complete 2022 ARCALYST revenue guidance will be shared with Q4 2021 financial results.
Kiniksa Pharmaceuticals (KNSA) announced its participation in the 40th Annual J.P. Morgan Healthcare Conference on January 10, 2022, at 1:30 p.m. ET. A live webcast of the presentation will be available on Kiniksa's website, with replays accessible within 48 hours post-event. The firm focuses on developing therapeutic medicines for diseases with significant unmet needs, featuring assets like ARCALYST® and mavrilimumab. For more details, visit www.kiniksa.com.
Kiniksa Pharmaceuticals (KNSA) announced that the Phase 3 trial for its investigational drug mavrilimumab, targeting COVID-19-related acute respiratory syndrome (ARDS), failed to meet its primary efficacy endpoint. The trial involved 582 patients and aimed to assess mavrilimumab's effectiveness in hospitalized patients with severe COVID-19 pneumonia. Despite the disappointing results, Kiniksa remains optimistic about mavrilimumab's potential and plans to focus on its ARCALYST franchise and other drug development programs, including vixarelimab and KPL-404.
Kiniksa Pharmaceuticals (Nasdaq: KNSA) will participate in a fireside chat at the Evercore ISI 4th Annual HealthCONx Conference on November 30, 2021, at 12:10 p.m. ET. The presentation will be available via live webcast on Kiniksa’s website, with a replay accessible approximately 48 hours post-event. Kiniksa is focused on developing therapeutic medicines for patients with significant unmet medical needs, boasting a portfolio including ARCALYST®, mavrilimumab, vixarelimab, and KPL-404, targeting various immunological conditions.
Kiniksa Pharmaceuticals reported Q3 2021 net revenue of $12.1 million from ARCALYST, with over 200 physicians prescribing the treatment for recurrent pericarditis. The company anticipates Phase 3 trial data for mavrilimumab in COVID-19-related ARDS in Q1 2022 and Phase 2b data for vixarelimab in prurigo nodularis in 2H 2022. Kiniksa forecasts Q4 2021 ARCALYST net revenue between $16.0 million and $17.0 million and projects sufficient cash to fund operations into 2023.
FAQ
What is the current stock price of Kiniksa Pharmaceuticals International, plc (KNSA)?
What is the market cap of Kiniksa Pharmaceuticals International, plc (KNSA)?
What is Kiniksa Pharmaceuticals' primary focus?
What are the key products in Kiniksa's pipeline?
What recent achievements has Kiniksa Pharmaceuticals reported?
What is ARCALYST used for?
When was Kiniksa's latest financial report released?
What is the expected revenue for ARCALYST in 2024?
What is abiprubart (KPL-404) targeting?
What are some of the conditions Kiniksa is targeting with its therapies?
Where can I find more information about Kiniksa Pharmaceuticals?
Who should be contacted for investor and media inquiries?
