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Johnson & Johnson (NYSE: JNJ) is an American multinational corporation founded in 1886, widely recognized as the world’s largest and most diversified healthcare company. The company is structured into three main segments: pharmaceuticals, medical devices and diagnostics, and consumer health products. The pharmaceutical division, which contributes significantly to the company's revenue, focuses on therapeutic areas such as immunology, oncology, neurology, pulmonary, cardiology, and metabolic diseases. The medical devices segment specializes in orthopedics, surgical instruments, and vision care. The consumer health division, known for products in baby care, beauty, oral care, over-the-counter drugs, and women's health, is set to be divested in 2023 under the new name Kenvue.
In recent developments, Johnson & Johnson has made headlines with the expanded approval of CARVYKTI® (ciltacabtagene autoleucel), a one-time infusion therapy for multiple myeloma. This approval is based on the successful Phase 3 CARTITUDE-4 study, showing a significant reduction in disease progression or death by 59% compared to traditional therapies. Such advancements underscore Johnson & Johnson's dedication to innovative treatments, particularly in oncology.
Financially, Johnson & Johnson generates over half of its revenue from the United States, with the pharmaceuticals and medical devices divisions driving the majority of cash flows. The company continues to invest heavily in research and development, aiming to transform healthcare through smarter and less invasive treatments. Their strategic partnerships and focus on emerging markets further cement their position as a leader in the healthcare industry.
With a commitment to improving global health, Johnson & Johnson's innovative solutions span across the full spectrum of healthcare, striving to prevent, treat, and cure complex diseases. For more information, visit their official website at www.jnj.com.
Johnson & Johnson (NYSE: JNJ) will participate virtually in the Credit Suisse 30th Annual Healthcare Conference on November 10, 2021. Ashley McEvoy, Executive Vice President and Worldwide Chairman of Medical Devices, will represent the company in a session at 11:20 a.m. ET. This event will be accessible to investors and interested parties via the Johnson & Johnson website. A webcast and podcast replay will be available about 48 hours post-event.
For more details, visit www.investor.jnj.com.
On October 6, 2021, Janssen Pharmaceutical Companies of Johnson & Johnson revealed groundbreaking preclinical data in Nature, showcasing a novel antiviral compound that may treat all dengue fever serotypes. The compound operates by obstructing key viral proteins, inhibiting replication, and demonstrating efficacy in both prevention and treatment settings. As dengue affects up to 400 million people annually, this advancement marks a significant step in addressing a critical public health issue. Janssen aims to escalate the compound's clinical development to deliver impactful solutions for at-risk communities.
Johnson & Johnson (NYSE: JNJ) announced the submission of data to the FDA for a booster shot of its COVID-19 vaccine for individuals aged 18 and older. Results from the Phase 3 ENSEMBLE 2 study show that a booster administered 56 days after the primary dose offers 94% protection against symptomatic COVID-19 and 100% against severe/critical cases. Additionally, Phase 1/2a data indicates a nine-fold increase in antibody levels after a booster at six months. The company plans further submissions to global health authorities to support vaccine administration strategies.
On September 21, 2021, Johnson & Johnson (NYSE: JNJ) shared new data affirming that its COVID-19 vaccine provides strong and long-lasting protection. A real-world effectiveness study indicated an efficacy rate of 79% for infections and 81% for hospitalizations. Additionally, a booster shot significantly enhanced protection, offering 94% efficacy against symptomatic COVID-19. The booster also heightened antibody levels by up to twelve times. The company has communicated these findings to regulatory agencies, including the FDA and WHO, as part of ongoing efforts to combat the pandemic.
Johnson & Johnson (NYSE: JNJ) will conduct a conference call on October 19, 2021, at 8:30 a.m. ET to review its third-quarter results. Hosted by Joseph J. Wolk, CFO, the call will feature key executives including Ashley McEvoy and Jennifer Taubert. Access the call via www.investor.jnj.com or by phone at 877-869-3847 (U.S.) and 201-689-8261 (international). Replay options will be available until November 2. The press release will be accessible at 6:45 a.m. ET that day.
On September 13, 2021, Johnson & Johnson (NYSE: JNJ) announced promising results for its Ebola vaccine regimen, Zabdeno® and Mvabea®, published in The Lancet Infectious Diseases. The Phase 3 EBOVAC-Salone study showed robust antibody responses in adults and children, persisting for at least two years. Booster doses further enhanced immune responses within a week. Conducted in Sierra Leone, the study demonstrated no safety concerns. The vaccine, granted EU marketing authorization in July 2020, aims to prevent future Ebola outbreaks, highlighting Johnson & Johnson's commitment to global public health.
Johnson & Johnson faces legal challenges as women with ovarian cancer seek a temporary restraining order against the company. They allege that J&J plans to transfer about $24 billion in potential talc-related liabilities to a subsidiary to seek bankruptcy protection, potentially limiting victim compensation. This move may halt ongoing litigation on a national scale. The legal strategy, known as the 'Texas Two-Step,' is seen as a way to evade financial responsibility. Critics argue that this abuse of bankruptcy threatens victims' rights to fair trials.
On August 26, 2021, a California jury awarded $26.5 million to a woman whose mesothelioma was linked to Johnson & Johnson's talcum powder products. This verdict adds to a growing trend of jury findings against J&J concerning the carcinogenic nature of talc. Reports reveal that a significant percentage of talc-based products sold by the company contained asbestos, which J&J allegedly concealed from the public and regulators. The company has indicated intentions to bundle such liabilities into a separate entity and pursue bankruptcy protection, raising concerns about accountability for victims.
Johnson & Johnson (NYSE: JNJ) announced that its Phase 2b Imbokodo HIV vaccine trial did not provide sufficient protection against HIV in young women in sub-Saharan Africa. While the vaccine showed a favorable safety profile, with no serious adverse events, the study will not continue. The trial involved over 2,600 participants, and the primary analysis indicated a vaccine efficacy of 25.2%, which was not statistically significant. Ongoing research from this trial may aid future HIV vaccine development. J&J continues its Phase 3 Mosaico study, testing a different vaccine regimen in men and transgender individuals.