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ImmunoPrecise Advances Anti-Aging Research with Mayo Clinic Study, Poised to Tap into $81 Billion Market with AI Technology

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ImmunoPrecise Antibodies (IPA) announces its contribution to a groundbreaking Mayo Clinic study on age-related mitochondrial dysfunction, published in the journal Autophagy. Using its proprietary rabbit B Cell Select™ platform, IPA developed specific antibodies targeting phosphorylated ubiquitin, a marker of mitochondrial damage common in aging and neurodegenerative diseases. The research advances understanding of conditions like Parkinson's and Alzheimer's. IPA is positioned to tap into the anti-aging market, projected to reach $81.01 billion by 2028 with an 8.2% CAGR. Through its subsidiary Talem Therapeutics, IPA maintains a pipeline focusing on therapeutic antibodies while supporting external research.

ImmunoPrecise Antibodies (IPA) annuncia il suo contributo a uno studio innovativo della Mayo Clinic sulla disfunzione mitocondriale legata all'età, pubblicato nella rivista Autophagy. Utilizzando la sua piattaforma proprietaria rabbit B Cell Select™, IPA ha sviluppato anticorpi specifici che mirano all'ubiquitina fosforilata, un marcatore di danno mitocondriale comune nell'invecchiamento e nelle malattie neurodegenerative. La ricerca avanza la comprensione di condizioni come il Parkinson e l'Alzheimer. IPA è posizionata per sfruttare il mercato anti-invecchiamento, che si prevede raggiungerà i 81,01 miliardi di dollari entro il 2028 con un CAGR dell'8,2%. Attraverso la sua sussidiaria Talem Therapeutics, IPA mantiene un pipeline focalizzato su anticorpi terapeutici mentre supporta la ricerca esterna.

ImmunoPrecise Antibodies (IPA) anuncia su contribución a un estudio innovador de la Mayo Clinic sobre la disfunción mitocondrial relacionada con la edad, publicado en la revista Autophagy. Utilizando su plataforma propietaria rabbit B Cell Select™, IPA desarrolló anticuerpos específicos dirigidos a la ubiquitina fosforilada, un marcador de daño mitocondrial común en el envejecimiento y las enfermedades neurodegenerativas. La investigación avanza en la comprensión de condiciones como el Parkinson y el Alzheimer. IPA está posicionada para aprovechar el mercado anti-envejecimiento, que se proyecta alcanzará los 81,01 mil millones de dólares para 2028 con un CAGR del 8,2%. A través de su filial Talem Therapeutics, IPA mantiene una cartera centrada en anticuerpos terapéuticos mientras apoya la investigación externa.

ImmunoPrecise Antibodies (IPA)는 Mayo Clinic에서 발표한 노화 관련 미토콘드리아 기능장애에 대한 혁신적인 연구에 기여했다고 발표했습니다. 자사의 독점 플랫폼인 rabbit B Cell Select™를 사용하여, IPA는 노화 및 신경퇴행성 질환에서 흔히 발견되는 미토콘드리아 손상의 표지자인 인산화 유비퀴틴을 겨냥한 특정 항체를 개발했습니다. 이 연구는 파킨슨병 및 알츠하이머병과 같은 질환에 대한 이해를 증진시킵니다. IPA는 2028년까지 810억 1천만 달러에 이를 것으로 예상되는 항노화 시장을 겨냥할 입장에 있습니다. IPA는 자회사인 Talem Therapeutics를 통해 치료 항체에 중점을 둔 파이프라인을 유지하며 외부 연구를 지원합니다.

ImmunoPrecise Antibodies (IPA) annonce sa contribution à une étude révolutionnaire de la Mayo Clinic sur la dysfonction mitochondriale liée à l'âge, publiée dans la revue Autophagy. En utilisant sa plateforme propriétaire rabbit B Cell Select™, IPA a développé des anticorps spécifiques ciblant l'ubiquitine phosphorylée, un marqueur des dommages mitochondriaux courants dans le vieillissement et les maladies neurodégénératives. La recherche fait avancer la compréhension de conditions telles que la maladie de Parkinson et d'Alzheimer. IPA est bien positionnée pour tirer parti du marché anti-vieillissement, qui devrait atteindre 81,01 milliards de dollars d'ici 2028, avec un taux de croissance annuel de 8,2 %. Grâce à sa filiale Talem Therapeutics, IPA maintient un pipeline axé sur les anticorps thérapeutiques tout en soutenant la recherche externe.

ImmunoPrecise Antibodies (IPA) kündigt seinen Beitrag zu einer bahnbrechenden Mayo Clinic-Studie über altersbedingte mitochondriale Dysfunktion an, die in der Zeitschrift Autophagy veröffentlicht wurde. Mit seiner proprietären rabbit B Cell Select™-Plattform entwickelte IPA spezifische Antikörper, die auf phosphoryliertes Ubiquitin abzielen, einen Marker für mitochondriale Schäden, die bei Alterung und neurodegenerativen Erkrankungen häufig vorkommen. Die Forschung fördert das Verständnis von Erkrankungen wie Parkinson und Alzheimer. IPA ist in einer Position, um den Anti-Aging-Markt zu erschließen, der bis 2028 voraussichtlich 81,01 Milliarden US-Dollar erreichen wird, mit einer CAGR von 8,2 %. Durch seine Tochtergesellschaft Talem Therapeutics hält IPA eine Pipeline aufrecht, die sich auf therapeutische Antikörper fokussiert und gleichzeitig externe Forschung unterstützt.

Positive
  • Strategic positioning in anti-aging market projected to reach $81.01B by 2028
  • Successful development of novel antibodies through proprietary B Cell Select platform
  • Partnership with prestigious Mayo Clinic validates technology capabilities
  • Dual revenue potential from external research support and internal therapeutic development
Negative
  • None.

Insights

This research collaboration with Mayo Clinic represents a strategic advancement in IPA's positioning within the anti-aging market. The development of novel antibodies targeting p-S65-Ub through their proprietary B Cell Select® platform demonstrates significant technical validation from a prestigious institution. However, while the $81.01 billion market opportunity is substantial, several steps remain before commercial realization.

The immediate revenue impact will likely be minimal, as these antibodies are currently research tools. The real value lies in the validation of IPA's platform technology and potential applications in diagnostic development. Their dual strategy of external collaborations while maintaining internal development through Talem Therapeutics provides multiple paths to market, though significant R&D investment will be required to capitalize on these opportunities.

The aging demographics and increasing focus on longevity science create a favorable market environment for IPA's technology. With a projected CAGR of 8.2% in the anti-aging market, the timing of this research breakthrough is opportune. The collaboration with Mayo Clinic enhances IPA's credibility and could attract additional research partnerships.

Given IPA's current market cap of $18.98 million, the company appears undervalued relative to the market opportunity. However, investors should note that commercialization timelines in biotech are typically lengthy and significant capital may be required to advance these discoveries toward market applications.

Rabbit B Cell Select® Platform Yields Novel Antibodies for Studying Age-Related Mitochondrial Dysfunction

VICTORIA, British Columbia--(BUSINESS WIRE)-- ImmunoPrecise Antibodies Ltd. ("IPA" or the "Company") (NASDAQ: IPA), an AI-driven biotherapeutic research and technology company, announces its significant contribution to a groundbreaking study. The research, led by top scientists at the Mayo Clinic, was initially published in bioRxiv and subsequently peer-reviewed and published in the prestigious journal Autophagy. Titled "Development and Characterization of Phospho-Ubiquitin Antibodies to Monitor PINK1-PRKN Signaling in Cells and Tissue," this study advances our understanding of how aging impacts mitochondrial health, a crucial factor in neurodegenerative diseases like Parkinson's and Alzheimer's.

The study focuses on the development of antibodies that detect damaged mitochondria, which are more common as we age. ImmunoPrecise played a crucial role in this project by applying its proprietary rabbit B Cell Select™ platform to isolate and generate highly specific antibodies that target phosphorylated ubiquitin (p-S65-Ub), a marker of mitochondrial damage. These antibodies allow researchers to measure mitochondrial health, and the progression of damage related to aging.

Dr. Jennifer Bath, CEO of ImmunoPrecise Antibodies, commented: "The development of these novel recombinant p-S65-Ub antibodies represents a significant advancement in mitochondrial research. IPA’s proprietary high-precision tools not only enhance our understanding of PINK1-PRKN mediated signaling, but also show promising biomarker potential for various clinical applications. We are proud to have contributed to this groundbreaking research, which opens new avenues for studying mitochondrial dysfunction in aging and neurodegenerative diseases, and may lead to improved diagnostic, prognostic, and therapeutic approaches."

IPA is strategically positioned to capitalize on the booming anti-aging market, projected to reach $81.01 billion by 2028 with an 8.2% CAGR. The Company's proprietary B cell Select platform demonstrates its innovative capacity in this high-growth sector. IPA's collaboration with Mayo Clinic showcases its ability to contribute to groundbreaking research in age-related diseases. Simultaneously, IPA maintains a robust internal pipeline through its subsidiary, Talem Therapeutics, focusing on next-generation therapeutic antibodies. This dual approach of supporting external research while developing proprietary assets establishes IPA as a versatile and valuable player in the longevity and aging fields, potentially unlocking significant market opportunities and shareholder value.

ImmunoPrecise's Contributions

ImmunoPrecise Antibodies (IPA) has made a significant contribution to this breakthrough study, showcasing yet another success from their proprietary rabbit B Cell Select™ platform. The Company's advanced antibody discovery process played a crucial role in the research. Utilizing the B Cell Select™ platform, IPA isolated specific immune cells from immunized rabbits. These cells were then meticulously screened to identify those producing antibodies highly specific to phosphorylated ubiquitin, a key indicator of mitochondrial damage. From the top-performing cells, IPA generated and validated recombinant antibodies, ensuring optimal sensitivity and accuracy in detecting damaged mitochondria. This achievement further demonstrates the power and versatility of IPA's rabbit B cell platform in producing high-quality, specific antibodies for cutting-edge research applications.

About ImmunoPrecise Antibodies Ltd.

ImmunoPrecise Antibodies Ltd. is a biotechnology company that leverages multi-omics modeling and complex artificial intelligence through a series proprietary and patented technologies. The Company owns an integrated end-to-end suite of capabilities to support the development of therapeutic antibodies and are known for solving very complex industry challenges. IPA has several subsidiaries in North America and Europe including entities such as Talem Therapeutics LLC, BioStrand BV, ImmunoPrecise Antibodies (Canada) Ltd. and ImmunoPrecise Antibodies (Europe) B.V. (collectively, the “IPA Family”).

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of applicable United States securities laws and Canadian securities laws. Forward-looking statements are often identified by the use of words such as “expects” “estimates”, “intends”, “anticipates” or “believes”, or variations of such words and phrases or state that certain actions, events or results “may”, “would”, “might” or “will” be taken, occur or be achieved. Forward-looking statements include, but are not limited to, statements relating to the expected outcome on the market, the life sciences, drug discovery and development, and clinical readiness or effectiveness of IPA-discovered therapeutics. Although the Company believes that we have a reasonable basis for each forward-looking statement, we caution you that these statements are based on a combination of facts and factors currently known by us and our expectations of the future, about which we cannot be certain. Our actual future results may be materially different from what we expect due to factors largely outside our control, including risks and uncertainties related to market and other conditions and the impact of general economic, industry or political conditions in the United States, Canada or internationally. You should also consult our quarterly and annual filings with the Canadian and U.S. securities commissions for additional information on risks and uncertainties. These forward-looking statements speak only as of the date of this press release and the Company undertakes no obligation to revise or update any forward-looking statements for any reason, even if new information becomes available in the future.

Forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements stated herein to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Actual results could differ materially from those currently anticipated due to a number of factors and risks, as discussed in the Company’s Annual Report on Form 20-F for the year ended April 30, 2024 (which may be viewed on the Company’s SEDAR+ profile at www.sedarplus.ca and EDGAR profile at www.sec.gov/edgar). Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results, performance, or achievements may vary materially from those expressed or implied by the forward-looking statements contained in this news release. Accordingly, readers should not place undue reliance on forward-looking statements contained in this news release. The forward-looking statements contained in this news release are made as of the date of this release and, accordingly, are subject to change after such date. The Company does not assume any obligation to update or revise any forward-looking statements, whether written or oral, that may be made from time to time by us or on our behalf, except as required by applicable law.

Source: ImmunoPrecise Antibodies Ltd.

Investor Relations

Kirsten Beduya

Quantum Media Group, LLC

kirsten@quantum-corp.com

Source: ImmunoPrecise Antibodies Ltd.

FAQ

What is the projected market value for anti-aging by 2028 according to IPA (NASDAQ: IPA)?

According to the press release, the anti-aging market is projected to reach $81.01 billion by 2028, growing at a CAGR of 8.2%.

What technology did ImmunoPrecise Antibodies (IPA) use in the Mayo Clinic study?

IPA used its proprietary rabbit B Cell Select™ platform to isolate and generate specific antibodies targeting phosphorylated ubiquitin (p-S65-Ub), a marker of mitochondrial damage.

What is the focus of the Mayo Clinic study involving ImmunoPrecise (IPA)?

The study focuses on developing antibodies to detect damaged mitochondria, which are more common in aging and relevant to neurodegenerative diseases like Parkinson's and Alzheimer's.

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