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Inhibitor Therapeutics, Inc. (INTI) is a Tampa-based company focusing on groundbreaking cancer treatments through angiogenesis inhibitors. Recently, they secured a licensing agreement with Johns Hopkins University for their patent on New Angiogenesis Inhibitors, targeting Prostate Cancer, Basal Cell Carcinoma, and Lung Cancer. Their innovative approach blocks blood vessel growth to combat tumor development, offering hope for patients with unmet medical needs.
Inhibitor Therapeutics, Inc. (OTCQB: INTI) has provided an update on its clinical development plan for an itraconazole formulation to treat Basal Cell Carcinomas in Gorlin Syndrome patients. The company has submitted a Pre-Investigational New Drug application (PIND) to the FDA and received preliminary comments. INTI has engaged Avior Bio to develop a new proprietary formulation of itraconazole, which will be bridged to the formulation used in their completed clinical study via a pharmacokinetic study.
The completed clinical study showed promising results, with 399 out of 477 targeted tumors showing reduction, 275 tumors (57.7%) achieving a clinically meaningful reduction of 30% or greater, and 130 tumors (27.3%) resolving completely. Inhibitor aims to submit an Investigational New Drug Application (IND) to the FDA by the end of Q1 2025.
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