Welcome to our dedicated page for Inovio Pharmaceuticals news (Ticker: INO), a resource for investors and traders seeking the latest updates and insights on Inovio Pharmaceuticals stock.
Inovio Pharmaceuticals, Inc. (NASDAQ: INO) is a pioneering United States-based biotechnology company dedicated to combating cancers and infectious diseases through DNA medicines. The company's innovative approach harnesses active DNA-based immunotherapies and vaccines to both treat and prevent these conditions.
Inovio's core technology revolves around its DNA plasmids, which are small circular DNA molecules crafted to produce specific proteins to target and fight diseases, delivered via their proprietary CELLECTRA® electroporation devices. This technology enables the body to produce its own disease-fighting proteins and immune responses, without the need for traditional adjuvants or nanoparticles.
The company's flagship candidate, INO-3107, targets Recurrent Respiratory Papillomatosis (RRP), a chronic and rare disease caused by HPV-6 and HPV-11. Inovio has shown significant clinical progress with INO-3107, and after receiving Breakthrough Therapy designation and Orphan Drug designation from both the FDA and the European Commission, it is on track to submit a Biologics License Application (BLA) under the FDA's accelerated approval program. With successful clinical trials demonstrating a robust immune response and a reduction in the need for surgical interventions, INO-3107 stands as a potential game-changer for RRP patients.
In addition to INO-3107, Inovio's expansive product pipeline includes several other promising candidates in various stages of development. These include INO-3112 for HPV-16/18 positive head and neck cancer, INO-4201 as an Ebola vaccine booster, and INO-5401 for glioblastoma, showcasing the versatility and broad applicability of the company's DNA medicine platform.
Inovio has established numerous strategic partnerships and collaborations to enhance its research and development efforts. Key partners include Roche, MedImmune, the University of Pennsylvania, DARPA, Drexel University, NIH, and the U.S. Military HIV Research Program. These collaborations not only bolster Inovio's scientific capabilities but also facilitate the swift advancement of its clinical programs.
Financially, Inovio has maintained a disciplined approach to managing its resources. The company recently projected its cash runway to extend into the second quarter of 2025, following positive feedback from the FDA on the accelerated approval pathway for INO-3107. This financial stability is crucial as Inovio prepares for potential commercialization of its lead candidates.
Inovio's commitment to innovation and its effective strategic execution position it as a formidable player in the biopharmaceutical industry, dedicated to bringing groundbreaking DNA medicine solutions to market. For more information, visit www.inovio.com.
INOVIO (NASDAQ:INO), a biotechnology company developing DNA medicines, announced its participation in four upcoming scientific conferences. These include:
1. AACR Special Conference in Boston, MA (Oct 19, 2024): Dr. Matthew Morrow will present a poster on INO-3107's impact on reducing surgical interventions for Recurrent Respiratory Papillomatosis (RRP).
2. ISV Congress 2024 in Seoul, Korea (Oct 22, 2024): Dr. Michael Sumner will give an oral presentation and poster on the clinical assessment of INO-3107 in adult RRP patients.
3. Fall Voice in Phoenix, AZ (Oct 25-26, 2024): Dr. Jeffrey Skolnik will present a poster on the clinical assessment of INO-3107 in adult RRP patients.
4. World Vaccine Congress Europe in Barcelona, Spain (Oct 28, 2024): Dr. Dave Liebowitz will give a presentation and participate in a panel discussion on platform technologies.
Abstracts from these conferences will be available on INOVIO's website after each presentation.
INOVIO (NASDAQ:INO), a biotechnology company specializing in DNA medicines, has announced its participation in the World Congress of Electroporation on September 18, 2024, in Rome, Italy. Trevor Smith, VP of Preclinical R&D at INOVIO, will deliver an oral presentation titled 'Development of in vivo-launched synthetic DNA-encoded antibodies employing CELLECTRA® electroporation technology' at 3:20pm CET.
This presentation aligns with INOVIO's focus on developing DNA medicines for HPV-related diseases, cancer, and infectious diseases. The company plans to make the abstract available on its website after the presentation, providing insights into their innovative approach using CELLECTRA® electroporation technology for DNA-encoded antibodies.
INOVIO (NASDAQ:INO) released its Q2 2024 financial results and recent business updates. Key developments include progress with INO-3107 for RRP, despite identifying a manufacturing issue delaying the BLA submission to mid-2025. All non-device elements of the BLA package are expected to be completed by year-end. The company plans to initiate confirmatory and redosing trials and advance regulatory efforts in Europe and the UK.
INO-3112 Phase 3 trial design submitted to European authorities, addressing HPV-16/-18 related throat cancer. INO-4201 Phase 2/3 clinical trial protocol resubmission to the FDA anticipated in Q3 2024.
Financial highlights: Cash and equivalents at $110.4M, down from $145.3M at the start of the year. R&D expenses were $23.1M, with a net loss of $32.2M this quarter. INOVIO's cash runway extends into Q3 2025 after raising $33.2M in a stock offering.
Steve Egge joined as Chief Commercial Officer to aid in commercial strategy and operations.
INOVIO (NASDAQ:INO) announced an equity grant under its 2022 Inducement Plan to a newly hired employee. The Compensation Committee of INOVIO's Board of Directors approved the award of 9,307 restricted stock units (RSUs) and an option to purchase 12,100 shares of common stock, effective July 31, 2024. The RSUs will vest over three years, with one-third vesting annually starting on the first anniversary of the grant date. The stock option has an exercise price of $10.66, INOVIO's closing price on the grant date, and will vest in four parts: one-fourth on the grant date and the rest annually over the next three years. Vesting is contingent on continued employment. These awards are governed by the terms of a stock option agreement and RSU award agreement under the Inducement Plan.
INOVIO (NASDAQ: INO), a biotechnology company focused on DNA medicines, announced that the European Medicines Agency's Committee for Advanced Therapies (CAT) has certified the quality and non-clinical data for INO-3107, their lead candidate for treating Recurrent Respiratory Papillomatosis (RRP). This certification confirms that INOVIO's chemistry, manufacturing and controls (CMC) data and nonclinical results comply with the scientific and technical standards used for evaluating a European Marketing Authorization Application.
The CAT certification provides an opportunity to identify potential development issues before submitting a Marketing Authorization Application, particularly beneficial for small and medium-sized enterprises. This regulatory achievement validates INOVIO's efforts to bring INO-3107 to RRP patients globally and demonstrates their development team's adherence to high standards.
INOVIO (NASDAQ:INO), a biotechnology company specializing in DNA medicines for HPV-associated diseases, cancer, and infectious diseases, has announced its plans to release second quarter 2024 financial results on August 8, 2024, after the market close. The company will host a live conference call and webcast at 4:30 p.m. ET on the same day to discuss the financial results and provide a general business update. The event will include a live Q&A session with analysts. Investors and interested parties can access the webcast through INOVIO's investor relations website. The webcast will be archived and available for replay for 90 days following the event.
INOVIO (NASDAQ: INO) has announced that its lead DNA medicine candidate, INO-3107, has been awarded the Innovation Passport designation under the U.K.'s Innovative Licensing and Access Pathway (ILAP). This designation is given to innovative medicines with the potential to meet a significant unmet medical need, accelerating their development and regulatory approval process.
INO-3107 is targeted at treating Recurrent Respiratory Papillomatosis (RRP), a rare and chronic disease caused by HPV-6 and HPV-11. The Innovation Passport facilitates a streamlined roadmap for regulatory approval, offering opportunities for enhanced regulatory input and accelerated timelines.
The ILAP, driven by multiple U.K. health authorities, aims to expedite the availability of promising medicines, particularly benefiting the post-Brexit life sciences landscape.
INOVIO announced the appointment of Steven Egge as Chief Commercial Officer, effective immediately. Bringing over 25 years of biopharmaceutical experience, Egge will spearhead INOVIO's commercial strategy as it moves towards becoming a commercial-stage company. The company plans to submit a Biologics License Application (BLA) for INO-3107 for recurrent respiratory papillomatosis (RRP) in the latter half of 2024 under the FDA's Accelerated Approval Pathway. This strategic hire aims to leverage Egge's extensive background in launching novel therapeutic products and building commercial organizations. His prior roles include key positions at Sumitomo Pharma and Merck, where he successfully led various product launches and market expansions.
INOVIO (NASDAQ: INO), a biotechnology company specializing in DNA medicines, announced an equity grant under its 2022 Inducement Plan. The grant comprises an option to purchase 1,400 shares of common stock, priced at $8.08 per share, which matches the stock's closing price on June 28, 2024. The grant was approved by INOVIO's Compensation Committee and issued to a newly hired employee as of June 30, 2024. The stock options will vest and become exercisable over four years, contingent on the employee's continued employment. This grant aligns with Nasdaq Listing Rule 5635(c)(4).
INOVIO (NASDAQ: INO), a biotechnology company, has been added to the Russell 2000® Index effective July 1, 2024. This inclusion is part of the annual reconstitution of the Russell stock indexes, which became effective after markets closed on June 28, 2024. INOVIO's CEO, Dr. Jacqueline Shea, noted that the last year has been transformational for the company, highlighting advancements with their lead candidate INO-3107 for RRP. The company plans to submit a BLA for INO-3107 under the FDA's accelerated approval pathway in late 2024 and aims for a commercial launch in 2025, pending approval. INOVIO is also progressing with other candidates like INO-3112 for head and neck cancer, INO-5401 for GBM, and INO-4201 as an Ebola vaccine booster. The Russell US Indexes, managed by FTSE Russell, capture the 4,000 largest U.S. stocks by market capitalization, with $10.5 trillion in assets benchmarked against them as of December 2023.
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