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Indaptus Therapeutics, Inc. (Nasdaq: INDP) is a pioneering pre-clinical biotechnology company focused on developing revolutionary treatments for cancer and certain infectious diseases. By harnessing the body’s innate and adaptive immune responses, Indaptus aims to cure disease through its proprietary platform that leverages bacteria's natural ability to activate both immune pathways.
The company’s flagship candidate, Decoy20, demonstrates significant promise in pre-clinical trials, showcasing single-agent activity and durable anti-tumor responses. These trials span various cancer models, including colorectal, hepatocellular, pancreatic carcinoma, and non-Hodgkin's lymphoma. Indaptus' technology involves the use of attenuated and killed non-pathogenic Gram-negative bacteria to safely elicit broad immune responses.
In line with its commitment to transparency and education, Indaptus actively engages with the public through social media platforms. The company shares updates on its groundbreaking research, educational content about cancer immunotherapy, and behind-the-scenes insights into its scientific progress. This engagement aims to build a community passionate about medical advancements.
Indaptus has recently advanced its innovative immunotherapy for the treatment of solid metastatic tumors into Phase 1 human trials. The safety and efficacy of Decoy20 in these trials have been promising, allowing the company to progress to multi-dosing regimens. This phase aims to further explore the safety and potential benefits of repeated Decoy20 administrations.
With a strong foundation built on over a century of immunotherapy advancements, Indaptus Therapeutics is poised to make significant strides in cancer and viral infection treatment. The company’s technology has shown potential in pre-clinical models to eradicate tumors when combined with other therapies, such as anti-PD-1 checkpoint inhibitors and low-dose chemotherapy.
Indaptus’ forward-looking strategy includes ongoing research and development activities, aiming to demonstrate the utility of its technology for treating solid tumors and chronic viral infections. The company's innovative approach, coupled with a robust pre-clinical pipeline, positions it uniquely in the biotechnology landscape, making it a noteworthy entity for investors and researchers alike.
Indaptus Therapeutics (Nasdaq: INDP) announced its participation in the H.C. Wainwright 26th Annual Global Investment Conference, scheduled for September 9-11, 2024, at the Lotte New York Palace Hotel. CEO Jeffrey A. Meckler will present a corporate overview on September 9, 2024, available on-demand starting at 7:00 AM Eastern Time.
The presentation will be accessible via webcast on the Indaptus website's investor relations section, with a replay available for approximately 90 days post-event. Meckler will also be available for one-on-one meetings throughout the conference. Interested parties can request meetings and register for the conference through the provided link.
Indaptus Therapeutics (Nasdaq: INDP) reported Q2 2024 financial results and provided a corporate update. Key highlights include:
- Completed a $3 million registered direct offering and private placement, netting $2.5 million
- Advancing Decoy20 clinical trial to weekly dosing
- Presented data at ASCO and AACR meetings
- R&D expenses increased to $1.7 million in Q2 2024
- G&A expenses rose to $2.4 million in Q2 2024
- Loss per share was $0.47 for Q2 2024
- Cash and equivalents stood at $7.3 million as of June 30, 2024
- Current cash expected to support operations into Q1 2025
Indaptus Therapeutics (Nasdaq: INDP) has announced a $3.0 million registered direct offering and concurrent private placement. The company will issue and sell 1,643,837 shares of common stock at $1.825 per share, along with unregistered warrants to purchase an equal number of shares. The warrants, exercisable at $1.70 per share, will have a five-year term. Paulson Investment Company, is acting as the exclusive placement agent. The offering is expected to close around August 8, 2024. Indaptus plans to use the net proceeds to fund research and development activities and for working capital and general corporate purposes.
Indaptus Therapeutics (Nasdaq: INDP), a clinical stage biotech company, will present new data on its lead product candidate, Decoy20, at the STING & TLR-Targeted Therapies Summit in San Diego on June 19-20, 2024. Chief Scientific Officer Dr. Michael Newman, newly named chair of the Summit, will present at 9:15 a.m. on June 20th, discussing the validation of the company’s 'Pulse-Prime' hypothesis through initial clinical data on Decoy20. CEO Jeffrey Meckler highlighted the company's advancements in immuno-oncology and its novel approach using engineered killed bacteria to stimulate the immune system in patients with advanced solid tumors.
Indaptus Therapeutics (Nasdaq: INDP) announced that Dr. Roger Waltzman, Chief Medical Officer, will present new data on their lead product candidate, Decoy20, at the 7th Annual Next-Gen Immuno-Oncology Conference in Boston on June 20-21, 2024. The presentation will cover preliminary results from an ongoing Phase 1 study involving Decoy20, an intravenous treatment aimed at stimulating the immune system using killed bacteria, targeting patients with advanced solid tumors. CEO Jeffrey Meckler expressed optimism about the findings and the opportunity to share continued updates.
Indaptus Therapeutics (Nasdaq: INDP) announced new data from its ongoing Phase 1 trial of Decoy20, presented at the ASCO Annual Meeting on June 1 in Chicago. The data shows that Decoy20 induces significant immune responses in patients with solid tumors, even at varying doses. The treatment was cleared from the blood within 120 minutes and resulted in manageable, lower-grade transient adverse events. Plasma biomarker analysis showed broad immune activation supporting the company’s 'pulse-prime' approach. CEO Jeffrey Meckler expressed optimism about the trial's progress, focusing on the potential anti-tumor activity as patient dosing increases.
Indaptus Therapeutics (Nasdaq: INDP), a clinical-stage biotech firm focused on cancer and viral infection treatments, announces participation in the Jefferies Global Healthcare Conference. CEO Jeffrey Meckler and CMO Dr. Roger Waltzman will present a corporate overview on June 5, 2024, at 8:00 AM ET. The event, held at Marriott Marquis in NYC, includes a live webcast accessible via Indaptus's investor relations webpage, with the replay available for 90 days.
Indaptus Therapeutics (Nasdaq: INDP) unveiled promising new data from their ongoing Phase 1 clinical trial of Decoy20 at the American Society of Clinical Oncology Annual Meeting 2024. The trial involves patients with advanced solid tumors.
The study highlighted Decoy20's pharmacokinetics and immune responses, showing that a single intravenous dose cleared from the bloodstream in 30-120 minutes and prompted the release of over 50 cytokines and chemokines, which are important for immune responses.
Remarkably, Decoy20 maintained a safety profile similar to that of purified lipopolysaccharide (LPS), with adverse effects being generally tolerable and resolving within 90 minutes to 3 days.
Indaptus CMO Roger Waltzman emphasized the significance of these findings and announced that the company would continue with the first multi-dose cohort, with updates expected throughout the year.
Indaptus Therapeutics announced the successful dosing of the first patient in the multi-dose phase of its Phase 1 clinical trial for Decoy20, a novel immuno-oncology therapy targeting advanced solid tumors.
The trial aims to determine the safety and efficacy of Decoy20 when administered multiple times. The initial single-dose phase was well-tolerated, and results will be presented at the ASCO meeting. Decoy20 activates both the innate and adaptive immune systems using broad immune agonists derived from Gram-negative bacteria, aiming to offer a new approach to cancer treatment.
CEO Jeffrey Meckler emphasized the potential of Decoy20 to address unmet medical needs in cancer therapy. The company plans to advance the therapy into combination studies with checkpoint inhibitors based on promising preclinical results.
Indaptus Therapeutics, Inc. (Nasdaq: INDP) reported first quarter 2024 financial results and provided a corporate update, highlighting progress in its clinical development plans. The company announced positive results from its Phase 1 clinical trial of Decoy20 and plans to present a poster at the American Society of Clinical Oncology (ASCO) Annual Meeting in June 2024. Financially, research and development expenses decreased by 15%, general and administrative expenses decreased by 9%, and loss per share improved. The company had cash and cash equivalents of $9.7 million as of March 31, 2024, with a cash runway expected to support operations through the third quarter of 2024.
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