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In8Bio, Inc. - INAB STOCK NEWS

Welcome to our dedicated page for In8Bio news (Ticker: INAB), a resource for investors and traders seeking the latest updates and insights on In8Bio stock.

Overview

In8Bio, Inc. is a clinical-stage biopharmaceutical company that specializes in the discovery, development, and commercialization of innovative gamma-delta T cell immunotherapies for cancer treatment. Utilizing state-of-the-art approaches such as allogeneic, autologous, and genetically modified T cells, the company is at the forefront of applying advanced immunology in the fight against both solid and hematologic malignancies. By leveraging its robust DeltEx platform, In8Bio is pioneering the integration of cell-based therapies into standard clinical protocols, a subject of high relevance in the fields of oncology and immunotherapy.

Clinical Programs and Technological Innovation

The company is deeply engaged in multiple clinical programs that advance its gamma-delta T cell product candidates into various stages of clinical investigation. Its innovative approach harnesses the unique ability of gamma-delta T cells to recognize and destroy cancer cells while differentiating between healthy and diseased tissues. The immunotherapies developed by In8Bio are designed to overcome current challenges in cancer treatment by demonstrating resilience in the presence of conventional modalities such as chemotherapy. This novel methodology indicates a significant step forward in addressing persistent gaps in progression-free survival for patients afflicted with difficult-to-treat cancers.

Pipeline and Portfolio

In8Bio maintains a diverse portfolio of cell therapy candidates that target both solid tumors, such as aggressive brain cancers, and liquid tumors, including high-risk hematologic malignancies. The company emphasizes the potential of its genetically modified gamma-delta T cells which are engineered to be chemotherapy-resistant, thereby enabling their effective use in combination with standard-of-care treatments. Its strategic portfolio reflects a deliberate focus on creating therapies that provide robust antitumor activity with a favorable safety profile, which is crucial in clinical settings.

Market Position and Competitive Landscape

Operating within a competitive and dynamic segment of the biotechnology and oncology markets, In8Bio distinguishes itself by being one of the first companies to translate genetically modified gamma-delta T cell therapy into clinical studies. The company’s efforts to integrate advanced cell therapy with conventional cancer management protocols underscore its role as a pioneer in the immunotherapy space. Its scientific and clinical strategies are rooted in extensive research, aiming to expand treatment options for patients with unmet medical needs while setting a benchmark for future research in cell-based therapies.

Research and Development Focus

The core of In8Bio’s business model lies in its commitment to rigorous research and clinical validation. The company employs a systematic approach to clinical investigation, ensuring that its product candidates are evaluated through well-designed studies. This commitment to science and robust clinical trial methodologies not only enhances the credibility of its findings but also contributes to the broader scientific understanding of gamma-delta T cell functions in oncology. The integration of innovative technologies with traditional treatment regimens speaks to the company’s strategy of enhancing therapeutic durability and safety.

Operational Excellence and Strategic Vision

In8Bio is characterized by its deep commitment to scientific excellence and operational transparency. Its research pipeline is supported by meticulous clinical studies that investigate both short-term efficacy and long-term safety profiles of its cell therapies. By positioning its programs at the interface of immunology and oncology, the company provides a pertinent example of how novel biotechnology can offer alternative options for cancer patients. This blend of advanced immunotherapeutic strategies and rigorous clinical science reinforces In8Bio’s reputation as a credible and knowledgeable entity in the biopharmaceutical landscape.

Investor Insights and Frequently Asked Questions

Investors and industry researchers looking into In8Bio will find that the company’s emphasis on gamma-delta T cell therapies offers a unique intersection of cellular immunotherapy and targeted cancer treatments. The detailed clinical programs, alongside strategic R&D initiatives, provide ample context on the company’s approach to addressing unmet needs in oncology. By maintaining a balanced perspective on both the promise and challenges inherent in advanced cell therapies, In8Bio continues to contribute to the evolution of cancer treatment paradigms with ongoing scientific rigor and clinical evaluation.

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IN8bio, Inc. (INAB) to present at Noble Capital Markets Emerging Growth Virtual Healthcare Equity Conference. CEO William Ho to discuss innovative gamma-delta T cell therapies. One-on-one meetings available for investors. Webcast to be archived for 90 days.
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IN8bio, Inc. (Nasdaq: INAB) announced promising preclinical data on its nsCAR platform, INB-300, showing improved selectivity in targeting leukemia cells while sparing healthy tissue. The technology aims to prevent off-target effects common in CAR-T therapies, potentially expanding treatment options for myeloid malignancies and solid tumors. Results presented at AACR 2024 revealed enhanced tumor killing capabilities without significant harm to healthy cells, indicating a 5.5x increase in selectivity. IN8bio plans to optimize the platform further for safer and more effective cancer treatments.
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IN8bio, Inc. (INAB) reported positive results from Phase 1 studies of INB-100 in leukemia and INB-200 in GBM, showcasing durable remissions and extended progression-free survival. The company closed a private placement, securing $14.4 million in gross proceeds, strengthening its financial position. Dr. Corinne Epperly joined the Board of Directors. IN8bio highlighted upcoming pipeline milestones and events, including Phase 2 studies and potential IND applications. Financially, R&D expenses increased due to program advancements, while G&A expenses decreased. The company reported a net loss of $7.6 million for Q4 2023 and had a cash position of $21.3 million as of December 31, 2023.
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IN8bio, Inc. (INAB) presents new preclinical data on its non-signaling gamma-delta T cell CAR platform targeting CD-33 and CD-123 at the AACR Annual Meeting. The platform shows promise in selectively targeting cancer cells while sparing healthy tissue, potentially addressing 'undruggable' tumor types.
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IN8bio, Inc. (INAB) CEO to present at investor conferences in March, showcasing innovative gamma-delta T cell therapies. Webcast available on the company's website.
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IN8bio, Inc. (NASDAQ: INAB) announces a publication in Frontiers in Immunology discussing their novel gamma-delta T cell therapy for glioblastoma. The therapy, DeltEx Drug Resistance Immunotherapy (DRI), aims to enhance the immune response against GBM while minimizing toxicity to healthy tissues. IN8bio's Phase 1 trial shows promising results with a possible improvement in progression-free survival.
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IN8bio, Inc. (NASDAQ: INAB) has announced positive data from clinical trials of its innovative gamma-delta T cell therapies INB-100, INB-200, and INB-400, with 100% durable complete remissions in leukemia patients and extended progression-free survival in glioblastoma multiforme patients. The company also closed a private placement, securing a cash runway into 2025.
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IN8bio, Inc. (Nasdaq: INAB) presents positive updated data from its Phase 1 investigator-sponsored trial of INB-100 at the 65th ASH Annual Meeting & Exposition. 100% of treated leukemia patients remain alive, progression-free, and in durable complete remission. INB-100 shows the first-ever durable persistence of an allogeneic cellular therapy, with expansion and persistence of allogeneic gamma-delta T cells 365 days post-administration. The trial is being expanded, and additional data is expected in 2024.
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IN8bio, Inc. (Nasdaq: INAB) has closed an initial round of fundraising, securing $14.4 million with the potential for an additional $32.5 million at increasing valuations. The company plans to use the proceeds to accelerate the development of its gamma-delta T cell therapies, extending its cash runway into 2025.
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IN8bio, Inc. (Nasdaq: INAB) appoints Corinne Epperly, MD, MPH, an internationally recognized immuno-oncology and cell therapy executive, to its Board of Directors. Dr. Epperly brings 20 years of experience in innovative immunotherapies for solid and hematological cancers, with a deep background at leading organizations such as Bristol Myers Squibb, Iovance Biotherapeutics, the National Cancer Institute, Goldman Sachs, and most recently CARGO Therapeutics. She will provide guidance on strategic, operational, scientific, and clinical matters related to the Company’s pipeline of gamma-delta T cell therapies.
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FAQ

What is the current stock price of In8Bio (INAB)?

The current stock price of In8Bio (INAB) is $0.1609 as of April 18, 2025.

What is the market cap of In8Bio (INAB)?

The market cap of In8Bio (INAB) is approximately 12.4M.

What is the primary focus of In8Bio, Inc.?

In8Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing gamma-delta T cell-based immunotherapies for the treatment of cancer.

How does In8Bio approach cancer treatment differently?

The company utilizes multiple strategies, including allogeneic, autologous, and genetically modified gamma-delta T cells, to create therapies that work in tandem with standard cancer treatments.

Which types of cancers does In8Bio target?

In8Bio develops therapies aimed at both solid tumors, such as aggressive brain cancers, and hematologic malignancies, addressing significant unmet clinical needs.

What makes the company’s technology innovative?

Their advanced DeltEx platform enables the development of T cell therapies that remain effective in the presence of chemotherapy while maintaining the cells’ natural ability to target cancer cells.

How does In8Bio ensure the safety of its therapies?

By conducting rigorous clinical trials that focus on both safety and efficacy, the company employs meticulous dosing and monitoring strategies to assess the performance of its cell therapies.

In what stage of development is In8Bio’s therapy pipeline?

In8Bio is in the clinical-stage phase, progressing several of its lead candidates through early and mid-stage clinical trials to validate safety and preliminary efficacy.

How does In8Bio differentiate itself from other biopharmaceutical companies?

In8Bio is one of the first to advance genetically modified gamma-delta T cells into clinical studies, positioning it as an innovator in a niche area of cell therapy.

What benefits do gamma-delta T cells offer in cancer treatment?

Gamma-delta T cells have the unique ability to differentiate between healthy and malignant cells, offering a promising therapeutic approach with potential improved safety and sustained antitumor activity.
In8Bio, Inc.

Nasdaq:INAB

INAB Rankings

INAB Stock Data

12.36M
72.48M
12.57%
36.96%
1.1%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States
NEW YORK