Welcome to our dedicated page for I-MAB American Depositary Shares news (Ticker: IMAB), a resource for investors and traders seeking the latest updates and insights on I-MAB American Depositary Shares stock.
I-Mab American Depositary Shares (Nasdaq: IMAB) represent a leading clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of novel and highly differentiated biologics to treat diseases with unmet medical needs, focusing on cancers and autoimmune disorders. With operations in Rockville, Maryland, and San Diego, California, I-Mab is actively involved in groundbreaking research and innovative drug development.
The company’s pipeline includes several promising candidates:
- Felzartamab (TJ202): A CD38 antibody in Phase III trials for multiple myeloma and autoimmune diseases.
- Eftansomatropin (TJ101): A long-acting human growth hormone that has completed Phase II trials for pediatric growth hormone deficiency.
- Olamkicept (TJ301): An IL-6 blocker in Phase II trials for ulcerative colitis and autoimmune diseases.
- Enoblituzumab: A humanized B7-H3 antibody that has completed Phase I trials for head and neck cancer and other oncology diseases.
- Efineptakin (TJ107): A long-acting recombinant human IL-7 in Phase II trials for glioblastoma multiforme (GBM).
I-Mab's innovative pipeline is driven by its internal R&D strategies, Fast-to-Proof-of-Concept, and Fast-to-Market development, often in collaboration with global partners. Recently, I-Mab announced the divestiture of its Chinese assets and operations, aiming to focus on the U.S. and other international markets. This strategic move included the transfer of its Greater China rights for various assets, potentially generating up to US$80 million based on future milestone achievements.
Notably, the company has entered into a clinical trial collaboration with Bristol Myers Squibb to evaluate givastomig combined with nivolumab and chemotherapy as a first-line treatment for advanced Claudin 18.2-positive gastric and esophageal cancers. I-Mab’s robust development pipeline and strategic global partnerships exemplify its commitment to advancing novel therapies to address critical medical needs.
For the latest updates and detailed information, visit the official website at I-Mab Biopharma.
I-Mab (Nasdaq: IMAB) and ABL Bio, Inc. have received FDA approval for their Investigational New Drug (IND) application to initiate a Phase 1 clinical trial for the bispecific antibody TJ-CD4B/ABL111. This trial aims to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of TJ-CD4B/ABL111 in patients with advanced or metastatic solid tumors. The antibody targets Claudin 18.2, enhancing immune response specifically at tumor sites while minimizing side effects. Both companies are optimistic about advancing this promising therapeutic option.
I-Mab (Nasdaq: IMAB) announced robust full-year results for 2020, achieving net revenues of RMB 1,542.7 million (US $236.4 million) and corporate profitability. Notably, the company has made significant strides in its clinical pipeline, achieving 18 milestones since its IPO, with three registrational trials currently underway. The New Drug Application for felzartamab (TJ202) is on track for submission in 2021. A global collaboration with AbbVie aims to advance the CD47 antibody lemzoparlimab (TJC4). The company holds a total cash position of RMB 4.8 billion (US $734.1 million), supporting operations through 2023.
I-Mab (Nasdaq: IMAB) will host its 2021 R&D Day with two sessions: a Mandarin session on April 7, 2021, at 14:00 CST, and an English session on April 26, 2021, from 8:00 am to 11:00 am EDT. Key presentations will feature Dr. Jingwu Zang and Dr. Joan Shen, focusing on I-Mab’s pipeline programs and R&D strategy. Investors can join via a live webcast available on the company’s Investor Relations site. I-Mab is transitioning into a fully integrated global biopharma company with over 15 clinical and pre-clinical stage candidates in the immuno-oncology sector.
I-Mab (Nasdaq: IMAB) announced the filing of a prospectus supplement with the SEC to register 19,050,555 ordinary shares held by Gaoling Fund and YHG Investment, in compliance with PIPE Agreements from September 2020. Hillhouse currently owns 13.3% of I-Mab's shares. This registration is part of a shelf registration statement filed on February 5, 2021. I-Mab, a clinical-stage biopharmaceutical company, focuses on immuno-oncology and has a pipeline of over 15 drug candidates, aiming for transformational medicines through innovative drug development.
I-Mab (NASDAQ: IMAB) announced a poster presentation at the 2021 AACR Annual Meeting showcasing uliledlimab (TJD5), a novel CD73 blocking antibody. This innovative treatment targets adenosine-rich cancer microenvironments with unique binding properties, providing potential anti-tumor activity in combination with PD-(L)1 therapies. Additionally, an abstract has been submitted for the phase 1 study of uliledlimab and atezolizumab, indicating ongoing clinical evaluation. The meeting will occur virtually from April 10-15, 2021.
I-Mab (Nasdaq: IMAB) has announced new collaborations with Complix and Affinity to enhance its drug discovery capabilities in immuno-oncology. These partnerships will provide access to advanced technology platforms including Cell Penetrating Alphabodies and tumor-site activated masked antibodies, aimed at developing innovative cancer therapeutics. The company remains focused on advancing its existing clinical programs while expanding its pipeline of novel drug candidates. I-Mab's strategy underscores its commitment to scientific leadership and innovation in the biopharmaceutical sector.
I-Mab (Nasdaq: IMAB), a biopharmaceutical firm, will announce its financial results for the full year ending December 31, 2020, before the market opens on March 29, 2021. A conference call is scheduled for 8:00 a.m. ET on the same day, where the company will provide a corporate update. I-Mab aims to advance from a clinical stage to a fully integrated company with a robust pipeline of over 15 drug candidates in the immuno-oncology field. The call requires prior registration, and a replay will be available on the company’s website.
I-Mab (Nasdaq: IMAB) has announced the dosing of the first patient in the pivotal phase 3 trial for eftansomatropin alfa, targeting pediatric growth hormone deficiency in China. This long-acting recombinant human growth hormone is designed to improve patient compliance by allowing weekly injections, in contrast to daily alternatives. The trial will enroll 165 patients, comparing eftansomatropin alfa with Norditropin over 52 weeks. A successful trial could significantly improve the quality of life for children with growth hormone deficiency, addressing a substantial unmet need in China.
I-Mab (Nasdaq: IMAB) announced its participation in several upcoming virtual conferences in March 2021. Key conferences include the H.C. Wainwright Global Life Sciences Conference on March 9, the Credit Suisse Asian Investment Conference from March 22-26, and the Morgan Stanley Hong Kong Summit from March 29-31. Notable management participants include Dr. Jingwu Zang, Dr. Joan Huaqiong Shen, and CFO Jielun Zhu. The company is committed to advancing its pipeline of biologics in the immuno-oncology sector, aiming for rapid commercialization and global presence.
I-Mab (Nasdaq: IMAB) announced the clearance of its IND application by China's NMPA for TJ210/MOR210, allowing the initiation of a phase 1 clinical trial. This trial aims to evaluate the drug's safety, tolerability, pharmacokinetics, and pharmacodynamics in patients with advanced solid tumors. TJ210/MOR210, a monoclonal antibody targeting C5aR1, is designed to block tumor-promoting immune cells. The trial follows similar studies in the U.S. and is expected to accelerate drug development for patients who have not responded to existing therapies.