Ferring Announces New Collaboration for Development of Olamkicept

• Strategic collaboration to further develop olamkicept highlights Ferring’s continued commitment to innovation in gastroenterology and inflammatory bowel disease.

• Olamkicept is the first and only clinical stage selective interleukin-6 (IL-6) inhibitor that works through the trans-signaling mechanism.

• IL-6 is associated with a number of inflammatory conditions, such as inflammatory bowel disease (IBD).

SAINT-PREX, Switzerland--(BUSINESS WIRE)-- Ferring Pharmaceuticals today announced it has entered into a strategic collaboration with I-Mab to further develop olamkicept in inflammatory bowel disease (IBD) and related inflammatory conditions.

Olamkicept is the first and only clinical stage selective interleukin-6 inhibitor that works through the trans-signaling mechanism. Interleukin-6 is associated with a number of inflammatory conditions, such as IBD. In 2021, positive results from a Phase 2 study evaluating the efficacy and safety of olamkicept in patients with active ulcerative colitis (UC) were presented at the European Crohn’s and Colitis Organization (ECCO) meeting.

Ferring had previously entered into a license agreement with I-Mab in 2016 that granted I-Mab exclusive rights to develop and commercialize olamkicept in Greater China and South Korea. This new collaboration enables Ferring to invest in the development of olamkicept globally and provides an option for I-Mab to collaborate with Ferring in the future development of olamkicept at a pre-defined development milestone. The financial details of this deal are undisclosed.

“Ferring is committed to developing novel therapies where unmet needs remain for patients living with complex medical conditions, including inflammatory bowel disease," said Araz Raoof, President of Ferring Research Institute and Senior Vice President, Global Drug Discovery & External Innovation at Ferring Pharmaceuticals. “We are excited to expand our collaboration and advance olamkicept globally, as we continue to invest in our specialty area of gastroenterology.”

About Ferring Pharmaceuticals

Ferring Pharmaceuticals is a research-driven, specialty biopharmaceutical group committed to helping people around the world build families and live better lives. Headquartered in Saint-Prex, Switzerland, Ferring is a leader in reproductive medicine and maternal health, and in specialty areas within gastroenterology and urology. Ferring has been developing treatments for mothers and babies for over 50 years and has a portfolio covering treatments from conception to birth. Founded in 1950, privately-owned Ferring now employs around 6,000 people worldwide, has its own operating subsidiaries in nearly 60 countries and markets its products in 110 countries.

Learn more at www.ferring.com, or connect with us on Twitter, Facebook, Instagram, LinkedIn and YouTube.

View source version on businesswire.com: https://www.businesswire.com/news/home/20220609005091/en/

For more information:

Bhavin Vaid

Head of Corporate Communications

+41 58 301 0952 (direct)

+41 79 191 0632 (mobile)

bhavin.vaid@ferring.com

Victoria Buenemann

Communications & Business Manager, R&D Strategy & Operations

+45 28 787 871 (mobile)

victoria.buenemann@ferring.com

Source: Ferring Pharmaceuticals

FAQ

What is the collaboration between I-Mab and Ferring Pharmaceuticals regarding IMAB?

Ferring Pharmaceuticals has partnered with I-Mab to develop olamkicept for inflammatory bowel disease (IBD), which is a strategic move to enhance its global market potential.

What is olamkicept and its significance in treating inflammatory bowel disease?

Olamkicept is the first clinical-stage selective interleukin-6 (IL-6) inhibitor, specifically targeting the trans-signaling pathway, crucial for treating inflammatory bowel disease.

What were the results of the Phase 2 study for olamkicept presented in 2021?

The Phase 2 study of olamkicept showed positive efficacy and safety results in patients with active ulcerative colitis, presented at the ECCO meeting in 2021.

What financial details are known about the collaboration between Ferring and I-Mab?

The financial details of the collaboration between Ferring Pharmaceuticals and I-Mab regarding olamkicept's development remain undisclosed.