Welcome to our dedicated page for Hoth Therapeutics news (Ticker: HOTH), a resource for investors and traders seeking the latest updates and insights on Hoth Therapeutics stock.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for dermatological disorders and other significant medical needs. The company focuses on conditions such as eczema, chronic wounds, psoriasis, asthma, and acne. Utilizing their proprietary BioLexa Platform, Hoth Therapeutics aims to create two topical cream products to treat eczema and reduce post-procedure infections in aesthetic dermatology patients.
Hoth Therapeutics has established numerous license and partnership agreements with prestigious institutions including The George Washington University, The University of Maryland Baltimore, Isoprene Pharmaceuticals, Inc., North Carolina State University, Chelexa Biosciences, Inc., The University of Cincinnati, and Zyla Therapeutics, Inc. Notably, Hoth is co-developing a topical treatment with Zyla Therapeutics for cutaneous lupus erythematosus, an autoimmune disease that severely impacts patient quality of life.
The company’s research collaborations extend to various areas including HT-001, a potential treatment for cancer patients experiencing skin toxicities from Epidermal Growth Factor Receptor Inhibitors (EGFRI). Hoth has recently received FDA clearance to proceed with protocol amendments in its ongoing Phase 2a clinical trials for HT-001, aiming to optimize clinical outcomes.
Hoth Therapeutics has also made strides in Alzheimer's Disease research with its HT-ALZ project, targeting neuroinflammation and cognitive deficits by antagonizing the NK1 receptor. Pre-clinical research has shown promising results in improving cognitive functions among Alzheimer's patients.
In addition to their pipeline, Hoth's subsidiary Merveille.ai has been pivotal in advancing obesity treatment using artificial intelligence. The discovery of a promising new therapeutic candidate for obesity, leveraging large language model technologies, underscores their commitment to innovative health solutions.
Financially, Hoth Therapeutics recently engaged in an agreement to exercise warrants, raising approximately $4.2 million to support its working capital needs. Their strategic partnership with Venable, LLP further strengthens their intellectual property protection, vital for ongoing and future therapeutic developments.
Collaborations with Wise Systems International SRL and integration of the Nvidia BioNeMo AI platform are set to enhance Hoth's drug discovery capabilities, leveraging artificial intelligence for cutting-edge therapeutic advancements.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced promising results for its novel anti-cancer therapeutic targeting mast cell neoplasms, demonstrating significant tumor reduction and apoptosis in humanized models. The mRNA frame shifting therapy was well-tolerated with no toxicity observed. Hoth aims to accelerate clinical trial initiation based on these findings, which could represent a major advancement in treating aggressive mast cell-derived cancers. The company emphasizes its commitment to research and development for unmet medical needs.
Hoth Therapeutics (NASDAQ: HOTH) has finalized the formulation of HT-001, aimed at alleviating cutaneous toxicities in cancer patients undergoing EGFR inhibitor therapy. This development allows the company to initiate IND-enabling toxicology studies, crucial for the upcoming Phase 2a clinical trial, pending IND approval. The formulation, created with input from top scientific advisors, has shown promising efficacy in preliminary tests. Hoth now focuses on completing necessary regulatory studies for HT-001.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) has partnered with Worldwide Clinical Trials for a Phase 2a dose-ranging clinical trial of HT-001. This trial aims to assess the efficacy and safety of HT-001 in treating cutaneous toxicities in cancer patients undergoing EGFR inhibitor therapy. The trial is a critical step toward an Investigational New Drug (IND) submission to the FDA, leveraging Worldwide's expertise in clinical studies. Hoth's focus is on addressing significant unmet medical needs associated with cancer treatment.
Hoth Therapeutics, Inc. (Nasdaq: HOTH) announced that the Brazilian Patent Office granted a notice of allowance for a patent application concerning a method to inhibit biofilm formation, issued on March 31, 2021. This new patent, noted by CEO Robb Knie, is part of the company's strategy to broaden its intellectual property portfolio in underserved global markets. The method, discovered by University of Cincinnati researchers, utilizes a zinc chelator to prevent biofilm creation by bacteria such as Staphylococcus epidermidis and Staphylococcus aureus.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced positive in vitro results for its lead peptide candidate HT-002, aimed at treating COVID-19. The study demonstrated that HT-002 inhibited 50% of the cytopathic effect of SARS-CoV-2 at an effective concentration (EC50) of 61.7 µM, with no observed cytotoxicity at concentrations up to 200 µM. Hoth plans further preclinical animal studies to explore the therapeutic potential and administration routes for HT-002, indicating a promising step in combating COVID-19.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced that CEO Robb Knie will present at the Benzinga Biotech Small Cap Conference on March 24, 2021, at 12:10 p.m. ET. Following this, he will join a panel discussion titled 'Coming Together to Address Unmet Medical Needs' at 12:50 p.m. ET.
Interested attendees can register for the webcast by visiting Benzinga's event page. Hoth Therapeutics focuses on developing therapies for dermatological disorders and has recently advanced vaccine projects for COVID-19.
Hoth Therapeutics, Inc. (Nasdaq: HOTH), a clinical-stage biopharmaceutical company, announced that CEO Robb Knie will feature in an exclusive interview on The RedChip Money Report airing on Bloomberg Television on March 20 at 7 p.m. ET. The segment, reaching 73 million homes in the U.S. and 100 million in Europe, will cover Hoth's focus on targeted therapeutics for unmet medical needs, highlighting its pipeline including the BioLexa Platform and HT-001.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) has entered into a research agreement with the University of Cincinnati Research Institute to conduct antimicrobial characterization studies for HT-006, a novel antibiotic targeting multi-drug resistant bacterial lung infections. The studies aim to expedite HT-006's development towards clinical use, addressing critical conditions like hospital-acquired pneumonia. Dr. Daniel Hassett will lead the research, which aligns with FDA guidelines for antibacterial therapies.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) has partnered with REPROCELL Ltd. to evaluate the HT-003 therapeutic platform's effects on ulcerative colitis and Crohn's disease tissues. This collaboration aims to characterize therapies for inflammatory bowel diseases, which affect around 3 million adults in the U.S. The active ingredient in HT-003 shows anti-inflammatory properties targeting retinoic acid metabolism. Hoth is working on multiple studies to meet unmet patient needs in various indications.
Hoth Therapeutics, Inc. (NASDAQ: HOTH) has successfully closed a private placement, raising $15.0 million through the issuance of 7,594,937 shares of common stock at $1.975 each. The offering also includes warrants with an exercise price of $1.86 per share. Proceeds will be used for product development and general corporate purposes. Hoth's largest shareholder has extended a one-year lockup agreement, which may stabilize share prices. The company is required to file a registration statement for the resale of shares within 15 days.
FAQ
What is the current stock price of Hoth Therapeutics (HOTH)?
What is the market cap of Hoth Therapeutics (HOTH)?
What is Hoth Therapeutics, Inc.?
What conditions does Hoth Therapeutics focus on?
What is the BioLexa Platform?
Who are some of Hoth Therapeutics' partners?
What is HT-001?
What recent advancements have been made in Alzheimer's Disease research by Hoth Therapeutics?
How is Hoth Therapeutics advancing obesity treatment?
What financial actions has Hoth Therapeutics recently taken?
What is the significance of Hoth Therapeutics' partnership with Venable, LLP?
How is artificial intelligence being used by Hoth Therapeutics?
