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Hepion Pharmaceuticals Announces Death of Director, Thomas Adams

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Hepion Pharmaceuticals (NASDAQ:HEPA) sadly reports the passing of Thomas Adams, Ph.D., a Board member, on January 9, 2022. Dr. Adams, who joined the Board in September 2016, was a renowned figure in biotechnology. The Chairman, Gary S. Jacob, expressed condolences, emphasizing Adams' significant contributions and impact on the company. Hepion's lead drug candidate, rencofilstat, is advancing in clinical-phase development for NASH and has received Fast Track designation from the FDA. The company is leveraging its AI platform, AI-POWR™, to enhance patient response in treatment and explore additional indications for rencofilstat.

Positive
  • Rencofilstat received Fast Track designation from the FDA for NASH treatment.
  • The investigational new drug (IND) application for rencofilstat, targeting hepatocellular carcinoma, was accepted by the FDA.
Negative
  • None.

EDISON, N.J., Jan. 12, 2022 (GLOBE NEWSWIRE) -- It is with profound sadness that Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA) announces the passing of Thomas Adams, Ph.D., a member of its Board of Directors. Dr. Adams died of natural causes on January 9, 2022.

A seasoned biotechnology veteran, Dr. Adams was appointed to Hepion’s Board in September 2016.

"We are deeply saddened by the loss of our dear friend and colleague,” said Hepion’s Chairman, Gary S. Jacob, Ph.D. “On behalf of the Company’s Board of Directors, management team and employees, I would like to extend our deepest sympathies to Tom’s family. Tom was a larger-than-life executive and entrepreneur, who brought his remarkable passion, experience and energy to Hepion. He will be greatly missed.”

About Hepion Pharmaceuticals

The Company's lead drug candidate, rencofilstat, is a potent inhibitor of cyclophilins, which are involved in many disease processes. Rencofilstat is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. Rencofilstat has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH, and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in nonclinical studies. In November 2021, the U.S. Food and Drug Administration (“FDA”) granted Fast Track designation for rencofilstat for the treatment of NASH. That was soon followed in December 2021 by the FDA’s acceptance of Hepion’s investigational new drug (IND) application for rencofilstat for the treatment of hepatocellular carcinoma (HCC).

Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to rencofilstat, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing NASH clinical development program, Hepion intends to use the platform to identify additional potential indications for rencofilstat to expand the company's footprint in the cyclophilin inhibition therapeutic space.

For further information, please contact:

Stephen Kilmer
Hepion Pharmaceuticals Investor Relations
Direct: (646) 274-3580
skilmer@hepionpharma.com


FAQ

What happened to Thomas Adams, a board member of Hepion Pharmaceuticals?

Thomas Adams, Ph.D., a member of the Board of Directors of Hepion Pharmaceuticals, passed away on January 9, 2022, due to natural causes.

What is rencofilstat and its significance for Hepion Pharmaceuticals?

Rencofilstat is Hepion's lead drug candidate, currently in clinical-phase development for NASH, showing potential in reducing liver fibrosis and related diseases.

What designations has rencofilstat received from the FDA?

Rencofilstat has received Fast Track designation from the FDA for the treatment of NASH and the IND application for hepatocellular carcinoma.

What is AI-POWR™ and its role in Hepion Pharmaceuticals?

AI-POWR™ is Hepion's proprietary AI platform aimed at identifying optimal NASH patients for rencofilstat, enhancing development timelines and patient outcomes.

Hepion Pharmaceuticals, Inc.

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