Welcome to our dedicated page for Harpoon Therapeutics news (Ticker: HARP), a resource for investors and traders seeking the latest updates and insights on Harpoon Therapeutics stock.
Harpoon Therapeutics, Inc. (NASDAQ: HARP) is a clinical-stage immunotherapy company founded in 2015. Specializing in developing T cell engagers, Harpoon harnesses the body’s immune system to combat cancer and other serious diseases. Co-founded by Patrick Bauerle and Luke Evnin, the company leverages groundbreaking T cell recruiting antibodies to develop next-generation therapies. Harpoon's innovative platforms include the Tri-specific T cell Activating Construct (TriTAC®), ProTriTAC™, and TriTAC-XR. The TriTAC® platform aims to direct a patient's own immune cells to target and destroy tumor cells, primarily focusing on solid tumors and hematologic malignancies.
One of Harpoon's leading projects is HPN328, targeting delta-like ligand 3 (DLL3). Currently in a Phase 1/2 clinical trial, HPN328 shows promise in treating small cell lung cancer (SCLC) and other neuroendocrine tumors. Interim results indicate a 35% confirmed response rate in all tumor types studied, with higher efficacy observed in non-SCLC neuroendocrine tumors.
Harpoon's innovative approach extends to their proprietary ProTriTAC™ platform, which remains inactive until reaching the tumor, ensuring higher precision and reduced side effects. Additionally, the TriTAC-XR platform is designed to mitigate cytokine release syndrome, a common challenge in T cell therapies.
Financially, Harpoon has secured robust funding through recent PIPE financings, ensuring a solid runway into 2026. Strategic partnerships with leading oncology research centers and a strong focus on regulatory milestones underscore Harpoon's commitment to advancing cancer treatment. For more information, visit www.harpoontx.com.
- HPN328 received Orphan Drug Designation from the FDA in March 2022.
- The company is actively presenting data at major oncology conferences such as ESMO and ASCO-GU.
- Harpoon plans to meet with regulators in early 2024 to discuss further development plans for HPN328.
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