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The CAR-T cell therapy market is projected to grow at an annualized rate of 23%, claims Roots Analysis

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The CAR-T cell therapy market is poised for significant growth, projected to reach a CAGR of 23% from 2022 to 2035. Over 970 therapies are currently approved or under development, with 25% in late-stage trials. The market's expansion is supported by substantial investments, totaling nearly USD 25 billion, primarily from US-based companies. Non-Hodgkin's lymphoma is expected to dominate the market, capturing 85% of target indications. The report highlights over 38,470 patients enrolled in around 750 clinical trials, indicating robust research and partnership activity.

Positive
  • Projected market growth of 23% CAGR from 2022 to 2035.
  • Over 970 CAR-T therapies approved or in development.
  • Significant investment of nearly USD 25 billion in CAR-T therapies.
  • Non-Hodgkin's lymphoma expected to capture 85% of the market share.
Negative
  • None.

As the six approved CAR-T cell therapies, including Breyanzi®, Abecma™ and CARVYKTI™ are poised to achieve blockbuster status, the field of CAR-T cell therapies has gained significant traction

LONDON, Feb. 16, 2023 /PRNewswire/ -- Roots Analysis has announced the addition of "Global CAR-T Cell Therapy Market (4th Edition), 2022-2035 " report to its list of offerings.

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CAR-T cell therapies have been shown to enable complete disease remission, omitting the need for any further treatment. Several studies have proven the efficacy of these therapy candidates. Driven by the ongoing pace of innovation and sufficient financial support from investors, the CAR-T cell therapy market is anticipated to witness substantial growth in the foreseen future

To order this 650+ page report, which features 350+ figures and 190+ tables, please visit https://www.rootsanalysis.com/reports/view_document/car-t-therapies-market/269.html

Key Market Insights

Over 970 CAR-T cell therapies are currently approved / under development

Over 25% of the aforementioned candidates are being evaluated in late-stage clinical trials (phase II and above), while 30% of them are in preclinical stage of development. More than 80% of the therapy candidates, which are being developed to target a range of disease indications, are autologous in nature. Further, CD19 and BCMA have emerged as the most popular target antigens.

Extensive efforts are underway to improve CAR constructs

Majority of the CAR-T cell therapies in clinical development, along with the six recently approved products, are based on second generation CARs. Further, lentivirus and retrovirus are presently the preferred type of vectors used for transduction of CAR constructs into T-cells. 

More than 38,470 patients have been enrolled in around 750 clinical trials, worldwide

Clinical research activity, in terms of number of trials registered, is reported to have increased over the last five years. Of the total number of trials, more than 90% are active and still recruiting patients, while close to 10% have already been completed.

Partnership activity within this domain has grown at a CAGR of 25%, between 2015 and 2021

Over 280 agreements have been inked in the last 5 years. Majority of partnership deals signed within this domain were licensing agreements (29%), R&D agreements (21%) and product development and commercialization agreements (12%).

Amount close to USD 25 billion has been invested by both private and public investors, across more than 260 instances 

Specifically, in 2020 and 2021, industry players raised over USD 6.1 billion. In addition, majority (42%) of the companies primarily received funding through venture capital rounds. Further, around 60% of the total funding instances were reported by players headquartered in the US.

More than 6,500 patents have been filed / published related to the CAR-T cell therapies

Close to 85% of these were patent applications, while around 15% were granted patents and others. Of the total granted applications, close to 45% were filed in North America and Europe.

The market is anticipated to grow at a CAGR of 23%, during the period 2022-2035

Currently, non-Hodgkin's lymphoma (85%) is anticipated to capture the highest target indication share; this trend is unlikely to change in the foreseen future. North America (primarily the US) and Europe are expected to capture close to 75% of the market share by 2035.

To request a sample copy / brochure of this report, please visit

 https://www.rootsanalysis.com/reports/view_document/car-t-therapies-market/269.html

Key Questions Answered

  • What are the prevalent R&D trends related to CAR-T cell therapies?
  • What are the different types of clinical conditions that can be treated using CAR-T cell therapies?
  • Who are the leading industry and non-industry players in this market?
  • In which geographies, extensive research on CAR-T cell therapy is being conducted?
  • What kind of partnership models are commonly adopted by industry stakeholders?
  • Who are the key investors in the CAR-T cell immunotherapy domain?
  • Who are the key opinion leaders / experts from renowned academic and research institutes proficient to help drive product development efforts in this domain?
  • How is the intellectual property landscape for global CAR-T cell therapies likely to evolve in the foreseen future?
  • Who are the key service providers (CMOs / CDMOs) with capabilities to develop and manufacture CAR-T cell therapies?
  • What are the key factors that are likely to influence the evolution of the CAR-T cell immunotherapies market?
  • How is the current and future market opportunity likely to be distributed across key market segments?
  • What are the key promotional strategies used by companies having marketed products?

The financial opportunity within the CAR-T cell therapies market has been analyzed across the following segments:

  • Target Indication(s)
    • Non-Hodgkin's Lymphoma
    • Multiple Myeloma
    • Acute Lymphoblastic Leukemia
    • Chronic Lymphocytic Leukemia
    • Hodgkin's Lymphoma
    • Acute Myeloid Leukemia
    • Ovarian Cancer
    • Generalized Myasthenia Gravis (MG)
    • Renal Cell Carcinoma
  • Target Antigen
    • CD19
    • BCMA
    • CD19/22
    • Others
  • Key Geographical Regions 
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East and North Africa
    • Rest of the World 

The report features inputs from eminent industry stakeholders, according to whom, T-cell immunotherapies are expected to be the next big step in cancer immunotherapy. The report includes detailed transcripts of discussions held with the following experts:

The report includes brief profiles of key players (listed below); each profile features an overview of the company, details related to its financial information (if available), details about CAR-T-cell based product(s), such as information on type of therapy and current development status, information on technology portfolio (if available), recent developments related to CAR-T cell immunotherapies and manufacturing capabilities of the players. 

  • Autolus
  • bluebird Bio
  • Bristol Myers Squibb
  • Carsgen Therapeutics
  • Cellectis
  • Cellular Biomedicine Group
  • Gilead Sciences
  • Innovative Cellular Therapeutics
  • Kuur Therapeutics
  • Noile-Immune Biotech
  • Novartis
  • Shanghai GeneChem
  • Sinobioway Cell Therapy
  • Takara Bio
  • Wellington Zhaotai Therapies

For additional details, please visit https://www.rootsanalysis.com/reports/view_document/car-t-therapies-market/269.html or email sales@rootsanalysis.com 

You may also be interested in the following titles:

  1. Global T-Cell (CAR-T, TCR, and TIL) Therapy Market (6th Edition), 2022- 2035
  2. Antiviral Drugs Market, 2022-2035
  3. mRNA Therapeutics and mRNA Vaccines Market (2nd Edition), 2022-2035 

https://www.rootsanalysis.com/reports/aseptic-filling-systems-market.html

Contact:

Gaurav Chaudhary
+1 (415) 800 3415
+44 (122) 391 1091
Gaurav.Chaudhary@rootsanalysis.com

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SOURCE Roots Analysis

FAQ

What is the projected growth rate of the CAR-T cell therapy market?

The CAR-T cell therapy market is projected to grow at a CAGR of 23% from 2022 to 2035.

How many CAR-T cell therapies are currently in development?

There are over 970 CAR-T therapies currently approved or under development.

What amount has been invested in CAR-T cell therapies?

Nearly USD 25 billion has been invested in CAR-T cell therapies.

What percentage of the CAR-T market is expected to be made up of Non-Hodgkin's lymphoma?

Non-Hodgkin's lymphoma is expected to capture 85% of the CAR-T market share.

How many patients are enrolled in clinical trials for CAR-T cell therapies?

More than 38,470 patients have been enrolled in around 750 clinical trials worldwide.

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