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GeoVax Labs, Inc. (OTCQB: GOVX) is a clinical-stage biotechnology company specializing in developing human vaccines and immunotherapies against infectious diseases and solid tumor cancers.
Utilizing novel proprietary platforms like the modified vaccinia ankara - virus-like particle (MVA-VLP) vaccine platform, GeoVax's pipeline includes ongoing human clinical trials for a next-generation COVID-19 vaccine and gene-directed therapy for head and neck cancers.
Additional research programs focus on preventive vaccines against infectious diseases like Monkeypox, hemorrhagic fever viruses (Ebola Zaire, Ebola Sudan, Marburg, and Lassa), and Zika virus, along with immunotherapies for various solid tumors.
Recent achievements include positive initial safety and immune response findings from a Phase 2 clinical trial evaluating GEO-CM04S1, the COVID-19 vaccine, as a heterologous booster in 63 healthy adults who previously received the Pfizer or Moderna mRNA vaccine. The trial has demonstrated statistically significant increases in neutralizing antibody responses against multiple SARS-CoV-2 variants.
GeoVax Labs (Nasdaq: GOVX) has received a Notice of Allowance from the U.S. Patent and Trademark Office for Patent Application No. 17/876,682, titled 'Vaccinia Viral Vectors Encoding Chimeric Virus Like Particles.' The patent strengthens protection for their vector platform expressing tumor-associated antigens in virus-like particles.
The company's MVA-VLP-MUC1 immunotherapy candidate showed promising preclinical results, achieving a 57% reduction in tumor growth when combined with anti-PD-1, and 100% prevention of tumor growth in a preventive model. GeoVax's patent portfolio now includes over 120 granted or pending applications across 24 patent families.
Additionally, GeoVax plans to initiate a Phase 2 clinical trial in first recurrent head and neck cancer for their lead oncology program Gedeptin® combined with an immune checkpoint inhibitor during first half 2025.
GeoVax Labs (Nasdaq: GOVX) announced that Chairman & CEO David Dodd will present at NobleCon20, the Noble Capital Markets Twentieth Annual Emerging Growth Equity Conference, on December 3, 2024, at 11:30 am ET in Boca Raton, FL. The presentation will be webcasted and available on GeoVax's website, Noble Capital Markets' Conference website, and Channelchek for 90 days.
GeoVax is advancing several clinical programs, including GEO-CM04S1, their next-generation COVID-19 vaccine, which recently received BARDA funding for a 10,000-participant Phase 2b trial. The company is also developing Gedeptin®, an oncolytic solid tumor therapy, with a Phase 2 clinical trial planned for first recurrent head and neck cancer in early 2025.
GeoVax Labs announced positive interim data from its Phase 2 clinical trial of GEO-CM04S1, a dual-antigen COVID-19 vaccine booster for chronic lymphocytic leukemia (CLL) patients. The Data Safety Monitoring Board's review showed that while the mRNA control arm failed to meet the primary endpoint, GeoVax's vaccine arm should continue enrollment. The study at City of Hope National Medical Center compares two injections of GEO-CM04S1 against an mRNA vaccine control. GEO-CM04S1 uses a modified vaccinia virus vector containing both Spike and Nucleocapsid antigens, potentially offering broader immune response and better protection for immunocompromised CLL patients who typically show insufficient responses to current COVID-19 vaccines.
GeoVax Labs reported its Q3 2024 financial results and business updates. The company recorded a net loss of $5.8 million ($0.91 per share) for Q3 2024, compared to $8.4 million in Q3 2023. Revenue from BARDA/RRPV Project NextGen was $2.8 million for Q3 2024. Key developments include progress in the GEO-CM04S1 BARDA Phase 2b trial, advancement of Gedeptin® towards Phase 2 clinical trials for head and neck cancer, and development of the GEO-MVA Mpox vaccine. The company reported cash balances of $8.6 million as of September 30, 2024.
GeoVax Labs (Nasdaq: GOVX) announced it will report its third quarter 2024 financial results on Tuesday, November 12, 2024, after U.S. markets close. The biotechnology company, which develops immunotherapies and vaccines against cancers and infectious diseases, will host a conference call and webcast with Q&A at 4:30 PM ET. Management will provide a corporate update and discuss financial results. Participants can access the call through registration, and an audio webcast archive will be available on the company's website for at least 90 days following the event.
GeoVax Labs, a biotechnology company focused on vaccine and cancer immunotherapy development, has announced its participation in the 3rd Annual ROTH Healthcare Opportunities Conference on October 9, 2024 in New York. David Dodd, the company's Chairman & CEO, will be part of a panel discussion on innovative therapies for solid tumors at 12:30 pm ET.
The company's senior management will also be available for one-on-one meetings with registered attendees. Interested parties can arrange meetings through their ROTH representative or by contacting GeoVax directly at info@geovax.com.
This participation highlights GeoVax's commitment to advancing its research and development in the field of cancer immunotherapies and human vaccines.
GeoVax Labs, Inc. (Nasdaq: GOVX), a biotechnology company focused on developing immunotherapies and vaccines, has announced its participation in two upcoming investor conferences in September 2024. Chairman and CEO David Dodd will present at both events:
1. H.C. Wainwright 26th Annual Global Investment Conference on September 9, 2024, at 7:00 a.m. ET in New York, NY.
2. Emerging Growth Conference on September 25, 2024, at 2:55 p.m. ET, which will be held virtually.
Both presentations will provide corporate updates on GeoVax. At the H.C. Wainwright conference, senior management will also host one-on-one meetings with registered attendees. Interested parties can contact GeoVax directly at info@geovax.com to arrange meetings.
GeoVax Labs, Inc. (Nasdaq: GOVX), a clinical-stage biotechnology company, has announced a registered direct offering priced at-the-market. The company will sell 975,610 shares of common stock (or equivalents) at $5.125 per share to an institutional investor. Additionally, in a concurrent private placement, GeoVax will issue warrants to purchase up to 975,610 shares at $5.00 per share, exercisable immediately with a five-year term.
The offering is expected to raise approximately $5.0 million in gross proceeds, before deducting fees and expenses. GeoVax plans to use the net proceeds for working capital and general corporate purposes. Roth Capital Partners is acting as the exclusive placement agent. The offering is anticipated to close around August 30, 2024, subject to customary closing conditions.
GeoVax Labs (Nasdaq: GOVX), a biotechnology company focused on developing immunotherapies and vaccines, has announced an upcoming webinar titled 'Now Is Not the Time to Monkey(pox) Around'. The event, scheduled for August 23, 2024, at 11:00am ET, will feature CEO David Dodd providing a detailed overview of Mpox, including insights on its rapid spread and methods for control, treatment, and prevention.
The webinar, hosted by Tribe Public , offers a complimentary registration for participants who can submit questions in advance or during the event. This presentation aims to address the growing concerns surrounding Mpox and highlight GeoVax Labs' potential role in combating the disease.
GeoVax Labs, Inc. (Nasdaq: GOVX) has announced a registered direct offering of 1,700,000 shares of common stock (or equivalents) at $5.00 per share, priced above-the-market. The biotechnology company is expected to raise approximately $8.5 million in gross proceeds. In a concurrent private placement, GeoVax will issue warrants to purchase up to 1,700,000 additional shares at $5.00 per share, exercisable immediately with a five-year term.
Roth Capital Partners is acting as the exclusive placement agent. The offering is expected to close around August 21, 2024. GeoVax intends to use the net proceeds for working capital and general corporate purposes. The offering is made pursuant to a previously filed and effective shelf registration statement.
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