Welcome to our dedicated page for Galecto news (Ticker: GLTO), a resource for investors and traders seeking the latest updates and insights on Galecto stock.
Galecto, Inc. (GLTO) is a clinical-stage biotechnology company at the forefront of developing innovative treatments for fibrosis and cancer. Founded in Lund, Sweden, and now incorporated in the U.S., Galecto focuses on small-molecule inhibitors targeting galectin-3 and lysyl oxidase-like 2 (LOXL2), proteins integral to the pathology of fibrosis and various cancers.
The company's lead product candidates include GB0139, GB1211, and GB2064. GB0139, initially developed for idiopathic pulmonary fibrosis (IPF), has shown promising preclinical results but recently failed to meet its primary endpoint in the Phase 2b GALACTIC-1 trial. Consequently, Galecto will discontinue its development and redirect resources.
GB1211, a selective oral galectin-3 inhibitor, targets severe liver diseases like non-alcoholic steatohepatitis (NASH) and liver cirrhosis. Encouraging results from the GULLIVER-2 trial underscored significant biomarker improvements and a favorable safety profile, setting the stage for the upcoming Phase 2a GULLIVER-3 trial in early 2024.
GB2064, an oral LOXL2 inhibitor, is in Phase 2a trials for myelofibrosis. Preliminary data indicate significant reductions in bone marrow fibrosis, validating the compound’s potential as a disease-modifying therapy.
Galecto's strategic partnerships and collaborations with top-tier scientists and biotech executives position it well for future growth. The company is also exploring GB1211's potential in oncology, specifically in combination with checkpoint inhibitors to overcome treatment resistance in cancers like non-small cell lung cancer (NSCLC) and melanoma.
With approximately $49 million in cash and investments, Galecto aims to extend its cash runway into 2025, focusing on advancing its promising pipeline of orally administered compounds.
For the latest updates and detailed information about Galecto, visit their website at www.galecto.com.
BOSTON, April 13, 2023 – Galecto, a clinical-stage biotechnology company focusing on treatments for fibrosis and cancer, will present two posters at the American Association for Cancer Research (AACR) Annual Meeting from April 14-19 in Orlando, Florida.
The company is conducting a Phase 2a trial of GB1211, a galectin-3 inhibitor, combined with atezolizumab for treating non-small cell lung cancer (NSCLC). Presenting data suggests that inhibiting galectin-1 and dual inhibition of galectin-1 and galectin-3 could offer new cancer therapies.
During the meeting, the following abstracts will be presented:
- Abstract LB104: Preclinical evaluation of Galectin-1 inhibitor on April 17.
- Abstract LB173: Benefits of blocking both Galectin-1 and Galectin-3 on April 18.
Galecto, Inc. (NASDAQ: GLTO) reported its operating and financial results for the year ended December 31, 2022. The company completed the enrollment of the Phase 2b GALACTIC-1 trial for GB0139 in idiopathic pulmonary fibrosis and has three compounds in Phase 2 clinical trials with positive results reported in 2022. Financially, cash equivalents totaled approximately $66.1 million, providing a runway into the second half of 2024. However, the net loss for the year was $61.6 million, resulting in a loss per share of $(2.43), compared to $(2.05) in the previous year. The company anticipates significant milestones in 2023, including key trial results.
BOSTON, March 02, 2023 – Galecto, a clinical-stage biotechnology company focused on fibrosis and cancer treatments, announced its participation in Oppenheimer’s 33rd Annual Healthcare Conference from March 13-15, 2023. Management will present on March 13 at 9:20 am EST and will be available for one-on-one meetings. A live webcast of the presentation can be accessed through Galecto's Investor website, with a replay available after the event.
Galecto's current clinical programs include four Phase 2 trials targeting idiopathic pulmonary fibrosis, myelofibrosis, liver cirrhosis, and non-small cell lung cancer, utilizing various galectin-3 and LOXL2 inhibitors.
BOSTON, Feb. 1, 2023 (GLOBE NEWSWIRE) -- Galecto, a clinical-stage biotechnology company focused on fibrosis and cancer treatments, will present at the SVB Securities Global Biopharma Conference from February 14-16, 2023. The presentation is scheduled for February 14th at 8:00 AM EST. A live webcast will be available on Galecto's Investor website, along with a replay following the event.
Currently, Galecto is developing small molecule inhibitors targeting galectin-3 and LOXL2, with four ongoing Phase 2 trials including treatments for idiopathic pulmonary fibrosis and non-small cell lung cancer.
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