Chinese Patent Granted for CytoMed Therapeutics' Licensed iPSC-Based Technology
- CytoMed's iPSC-based technology has been granted a patent by the China National Intellectual Property Administration (CNIPA)
- The patent covers technologies to derive synthetic γδ NKT cells for the treatment of various types of cancers including hematological malignancies and solid tumors
- The grant of the patent strengthens CytoMed's existing suite of patents
- None.
"We're thrilled to strengthen our existing suite of patents," said Peter Choo, Chairman of CytoMed. "Now this novel iPSC-based technology has been granted patent in
For cancer treatment, immune cells such as γδ T cells and natural killer (NK) cells are invaluable therapeutic cells due to their ability to express an array of built-in receptors that recognize stress-induced cancer antigens naturally.
By combining the iPSC technology and directed differentiation, CytoMed can generate a novel type of synthetic hybrid immune cells, γδ NKT cells, that express cancer recognition receptors of both γδ T cells and NK cells to recognize a wide range of cancers without genetic modification or use of viral vectors. As an allogeneic cell source, the Company's iPSC-derived γδ NKT cells may potentially become an "off-the-shelf" cell therapy that is applicable to a large pool of patients.
The patent titled "Methods and Kits for Generating Mimetic Innate Immune Cells from Pluripotent Stem Cells" with Patent No. ZL201880022790.X, published as CN 110691844 B, covers technologies to derive novel synthetic γδ NKT cells for the treatment of various types of cancers including hematological malignancies and solid tumors. This asset is currently under preclinical development. The Company holds an exclusive, worldwide license to use this patent pursuant to the Licence Agreement dated June 1, 2018, which was filed with the Securities and Exchange Commission as an exhibit to the registration statement on Form F-1 (File No.: 333-268456) on March 30, 2023.
About CytoMed Therapeutics Limited (CytoMed)
Incorporated in 2018, CytoMed was spun off from the Agency for Science, Technology and Research (A*STAR),
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SOURCE CytoMed Therapeutics Limited
