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4DMT Announces Presentations at ARVO 2024 Annual Meeting

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4DMT, a genetic medicines company, announced presentations at the 2024 ARVO Annual Meeting, including interim results from the PRISM Phase 2 trial for 4D-150 and preclinical data on 4D-175. The Company aims to treat diseases like AMD through genetic medicine.

4DMT, un'azienda di medicina genetica, ha annunciato presentazioni all'incontro annuale ARVO 2024, inclusi risultati intermedi dalla sperimentazione di Fase 2 PRISM per il 4D-150 e dati preclinici su 4D-175. L'obiettivo dell'azienda è trattare malattie come l'AMD attraverso la medicina genetica.
4DMT, una compañía de medicinas genéticas, anunció presentaciones en la Reunión Anual de ARVO 2024, incluyendo resultados intermedios del ensayo de Fase 2 PRISM para 4D-150 y datos preclínicos sobre 4D-175. La empresa pretende tratar enfermedades como la AMD mediante la medicina genética.
유전 의학 회사인 4DMT는 2024년 ARVO 연례 회의에서 발표를 발표했습니다. 이 발표에는 4D-150을 위한 PRISM 2상 시험의 중간 결과와 4D-175에 대한 전임상 데이터가 포함되어 있습니다. 이 회사는 유전 의학을 통해 AMD와 같은 질병을 치료하고자 합니다.
4DMT, une entreprise spécialisée en médecine génétique, a annoncé des présentations à la réunion annuelle de l'ARVO 2024, incluant des résultats intermédiaires de l'essai de phase 2 PRISM pour le 4D-150 et des données précliniques sur le 4D-175. L'entreprise vise à traiter des maladies telles que la DMLA à travers la médecine génétique.
4DMT, ein Unternehmen für genetische Medizin, gab Präsentationen auf der ARVO-Jahrestagung 2024 bekannt, einschließlich Zwischenergebnisse der PRISM Phase 2-Studie für 4D-150 und präklinischer Daten zu 4D-175. Das Unternehmen zielt darauf ab, Krankheiten wie AMD durch genetische Medizin zu behandeln.
Positive
  • 4DMT showcasing progress in genetic medicines development at a prestigious event like ARVO Annual Meeting.
Negative
  • information provided on the actual results of the presentations and their impact on the Company's future prospects.
  • Preclinical data for 4D-175 for geographic atrophy to be presented in an oral presentation
  • 4D-150 PRISM randomized Phase 2 Dose Expansion Cohort (N=51) 24-week encore results to be presented in a poster

EMERYVILLE, Calif., May 01, 2024 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (Nasdaq: FDMT, 4DMT or the Company), a leading clinical-stage genetic medicines company focused on unlocking the full potential of genetic medicines to treat large market diseases, today announced presentations at the 2024 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting in Seattle, Washington on May 5-9, 2024.

2024 ARVO Annual Meeting Presentation Details:

Title:Interim results from the PRISM randomized Phase 2 Dose Expansion trial evaluating 4D-150 in high anti-VEGF need individuals with neovascular (wet) age-related macular degeneration
Poster Session:AMD-3 (clinical research), 416 (Poster A0075)
Date/Time:Wednesday, May 8, 2024 (10:30 a.m. PT)
Presenter:Arshad M. Khanani, M.D., M.A., FASRS, Director of Clinical Research at Sierra Eye Associates, Clinical Associate Professor at University of Nevada, Reno School of Medicine


Title:Preclinical characterization of 4D-175, a novel AAV-based investigational intravitreal gene therapy for geographic atrophy
Paper (Oral) Session:AMD: Translational studies, 522
Date/Time:Thursday, May 9, 2024 (12:00 p.m. PT)
Presenter:Melissa A. Calton, Ph.D., VP, Early-Stage Product Development at 4DMT


The presentations will also be available on the 4DMT website under Scientific Presentations:
https://4dmoleculartherapeutics.com/pipeline/#posters-and-publications

About 4DMT 

4DMT is a leading clinical-stage genetic medicines company focused on unlocking the full potential of genetic medicines to treat large market diseases in ophthalmology and pulmonology. 4DMT’s proprietary invention platform, Therapeutic Vector Evolution, combines the power of the Nobel Prize-winning technology, directed evolution, with approximately one billion synthetic AAV capsid-derived sequences to invent customized and evolved vectors for use in our wholly owned and partnered product candidates. Our product design, development, and manufacturing engine help us efficiently create and advance our diverse product pipeline with the goal of revolutionizing medicine with potential curative therapies for millions of patients. Currently, 4DMT is advancing five clinical-stage and two preclinical product candidates, each tailored to address rare and large market diseases in ophthalmology, pulmonology, and cardiology. In addition, 4DMT is also advancing programs in CNS through a gene editing partnership. 4D Molecular Therapeutics™, 4DMT®, 4D®, Therapeutic Vector Evolution™, and the 4DMT logo are trademarks of 4DMT.

All of our product candidates are in clinical or preclinical development and have not yet been approved for marketing by the FDA or any other regulatory authority. No representation is made as to the safety or effectiveness of our product candidates for the therapeutic uses for which they are being studied.

Learn more at www.4DMT.com and follow us on LinkedIn.

Contacts:

Media:

Katherine Smith
Inizio Evoke Comms
Katherine.Smith@inizioevoke.com

Investors:

Julian Pei
Head of Investor Relations and Corporate Finance
Investor.Relations@4DMT.com


FAQ

What was announced by 4DMT at the ARVO 2024 Annual Meeting?

4DMT announced presentations on 4D-150 interim results and 4D-175 preclinical data.

When will the presentations take place?

The presentations will be held on May 8 and May 9, 2024.

What is the focus of the PRISM Phase 2 trial for 4D-150?

The PRISM trial evaluates 4D-150 in individuals with neovascular age-related macular degeneration.

Who will be presenting the preclinical characterization of 4D-175?

Melissa A. Calton, Ph.D., VP at 4DMT, will present the data on 4D-175 gene therapy.

Where can the presentations be accessed?

The presentations will be available on the 4DMT website under Scientific Presentations.

What is 4DMT's focus as a company?

4DMT focuses on genetic medicines to treat large market diseases like AMD.

4D Molecular Therapeutics, Inc.

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Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
EMERYVILLE