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FibroBiologics, Inc. (Nasdaq: FBLG) is a clinical-stage biotechnology company based in Houston, specializing in the development and commercialization of fibroblast-based therapies for treating a range of chronic diseases with unmet medical needs. These include degenerative disc disease, multiple sclerosis, wound healing, certain cancers, and potential life-extending applications like thymic and splenic involution reversal.
Core Business and Focus: The company leverages human dermal fibroblasts (HDFs) to develop innovative treatments aimed at reducing inflammation and promoting tissue regeneration. Their technology is backed by over 150 issued and pending patents across multiple clinical pathways.
Recent Achievements: FibroBiologics recently presented promising preclinical data at the 2024 Keystone Symposia for Systemic Autoimmune and Autoinflammatory Diseases. The study demonstrated the efficacy of HDF spheroids in treating psoriasis in a mouse model, significantly reducing skin lesion severity and autoimmune inflammation.
Current Projects: Ongoing research includes the development of fibroblast-based pancreatic beta cell spheroids to secrete insulin in vitro, which could become a groundbreaking treatment for insulin-dependent diabetes. Additionally, the company is exploring the use of HDF spheroids for accelerating wound healing in diabetic patients.
Financial Condition: FibroBiologics has recently filed its Annual Report on Form 10-K for the year ended December 31, 2023, showcasing strong financial health and strategic advancements in their clinical programs.
Partnerships: To expedite the clinical translation of their fibroblast-based therapies, FibroBiologics is collaborating with Charles River to optimize cell manufacturing processes and ensure high-quality drug product development for clinical trials.
FibroBiologics represents the next generation of medical advancement in cell therapy, continually pushing the boundaries of regenerative medicine to bring innovative treatments to patients worldwide.
FibroBiologics, a clinical-stage biotechnology company with a focus on developing therapeutics for chronic diseases, will present a corporate update at the 2024 BIO International Convention. The company, which recently went public, aims to showcase its advancements in fibroblast-based therapies for various indications. FibroBiologics holds numerous patents in areas like disc degeneration, orthopedics, multiple sclerosis, wound healing, organ involution reversal, and cancer treatment.
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