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Evogene Ltd. (Nasdaq: EVGN, TASE: EVGN) is a leading computational biology company leveraging big data and artificial intelligence to revolutionize the development of life-science-based products. The company, headquartered in Rehovot, Israel, employs cutting-edge technologies to increase the probability of success while reducing development time and cost across multiple market segments including human health, agriculture, and industrial applications. Evogene has established three unique tech-engines - MicroBoost AI, ChemPass AI, and GeneRator AI - each focused on products based on microbes, small molecules, and genetic elements respectively.
The company operates through several subsidiaries that utilize these tech-engines:
- Biomica Ltd.: Develops microbiome-based therapeutics for diseases such as antibiotic-resistant bacteria, cancer, and gastrointestinal disorders.
- Lavie Bio Ltd.: Focuses on microbiome-based ag-biologicals to enhance crop yield and sustainability.
- AgPlenus Ltd.: Innovates in sustainable crop protection products.
- Canonic Ltd.: Develops medical cannabis products.
- Casterra Ag Ltd.: Produces high-yield castor seeds for biofuels and other industrial uses.
Evogene's recent achievements include securing new seed production agreements for Casterra, advancing clinical trials for Biomica's immuno-oncology candidate BMC128, and extending validation trials for Lavie Bio's biofungicides in collaboration with Bayer AG. Evogene has been proactive in addressing its Nasdaq listing compliance and continues to prioritize innovation through strategic partnerships and collaborative ventures. For more information, please visit www.evogene.com.
Plastomics and Evogene Ltd. (NASDAQ: EVGN) announced a collaboration to develop novel insect control traits for soybeans. Utilizing Plastomics' transformative chloroplast technology, Evogene's insect control genes will be introduced into soybeans to combat insect resistance. The global biotech seed market is projected to reach US$45 Billion by 2027, with soybean traits expected to grow at a 6.7% annual rate. This partnership aims to deliver innovative solutions to soybean growers, leveraging artificial intelligence and advanced gene delivery methods.
Evogene Ltd. (NASDAQ: EVGN) announced its financial results for 2020, highlighting a cash position of approximately $48.2 million by year-end. The company reported a consolidated net cash usage of $19.3 million for the year, with expectations of increased usage in 2021-2022 as subsidiaries progress in product development. The operating loss for 2020 was $24.8 million, up from $21.2 million in 2019. Despite increased expenses, Evogene is optimistic about its subsidiaries' advancements, particularly in immuno-oncology and herbicides, aiming for commercialization milestones in the near future.
On February 24, 2021, Cannbit Ltd. and Canonic Ltd., both leaders in the medical cannabis sector, announced a collaboration to develop novel cannabis products. The partnership aims to leverage Cannbit's extensive clinical data and Canonic's advanced computational biology platform to address key challenges in the cannabis industry. Each company will retain full commercial rights to the products developed, with cross-royalties in place. Financial terms were not disclosed, but both companies expressed optimism about the competitive advantage this collaboration could provide.
On February 24, 2021, Cannbit, a subsidiary of Tikun Olam-Cannbit, and Canonic, a subsidiary of Evogene (NASDAQ: EVGN), announced a collaboration to develop novel medical cannabis products. This agreement aims to combine Cannbit's extensive clinical data and Canonic's computational biology platform to address challenges in the medical cannabis industry. Both companies will have full commercial rights to the products developed, with cross royalties in place. Financial details were not disclosed, but the collaboration is seen as a strategic growth opportunity for both firms.
Evogene Ltd. (NASDAQ: EVGN) announced it will release its financial results for Q4 and full-year 2020 on March 3, 2021. The company aims to revolutionize life-science product development through its Computational Predictive Biology platform, applicable in human health and agriculture. During the release, Dr. Arnon Heyman, CEO of Canonic Ltd., will discuss its activities. A conference call is scheduled at 09:00 AM ET, with access available via phone and live webcast. A replay will be accessible following the call until March 5, 2021.
Biomica Ltd., a subsidiary of Evogene Ltd. (NASDAQ: EVGN), announced its participation in the Crohn's & Colitis Congress® taking place virtually from January 21-24, 2021. Prof. Yehuda Ringel will present on the live bacterial consortium BMC322, developed for treating inflammatory bowel disorders (IBD), during a session on January 23 at 2 PM (EST). The study's abstract was recognized for its high quality, ranking in the top 10% of submissions.
Biomica specializes in microbiome-based therapeutics, focusing on conditions like antibiotic resistance and GI disorders.
Biomica Ltd., a subsidiary of Evogene (NASDAQ: EVGN), will present at the Microbiome Movement Drug Development Europe Conference on January 28-29, 2021. CEO Dr. Elran Haber will participate in a panel discussing strategies for microbiome-based therapeutics, while VP Dr. Shiri Meshner will unveil pre-clinical trial results from their immune-oncology program. The conference aims to explore market strategies and regulatory support for the microbiome sector. Biomica focuses on innovative microbiome-based therapies addressing antibiotic resistance and gastrointestinal disorders.
Evogene Ltd. (NASDAQ: EVGN) announced a year-end update for the CRISPR-IL consortium, with Dr. Eyal Emmanuel as Chairman. The consortium completed the first version of the AI-driven genome-editing platform, "Go-Genome," improving precision and efficiency. New members Better Seeds and FreeZem joined, expanding the platform's applicability. The CRISPR-CAS technology aims to develop therapeutics and agricultural products, targeting a $500 billion market by 2025. The consortium addresses challenges such as off-target edits and inefficient modifications, positioning Evogene at the forefront of CRISPR technology.
Lavie Bio, a subsidiary of Evogene (NASDAQ: EVGN), announced progress on its product pipeline for 2020, highlighting the advancement of bio-stimulant LAV211 towards a commercial launch planned for 2022. LAV211, targeting spring wheat, aims to benefit farmers by enhancing productivity, potentially delivering an additional $20 per acre. The company also detailed advancements in its bio-pesticides, specifically LAV311 and LAV312, which target bunch rot diseases and are set for launch in 2024. Lavie Bio's innovative approach utilizes its Biology Driven Design platform, enhancing its product development.
Canonic Ltd., a subsidiary of Evogene Ltd. (NASDAQ: EVGN), has signed its first commercial agreement with Telcann Ltd. to provide plant growth services in Israel. This agreement completes a crucial step in Canonic's medical cannabis production infrastructure, allowing them to launch their products, MetaYield and Precise, starting in 2022. The Israeli medical cannabis market is projected to grow significantly, with estimates reaching 250,000 active patients by 2025, representing a potential $220 million annual market.
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