Welcome to our dedicated page for Esperion Therapeutics news (Ticker: ESPR), a resource for investors and traders seeking the latest updates and insights on Esperion Therapeutics stock.
Esperion Therapeutics, Inc. (NASDAQ: ESPR) is a leading pharmaceutical company specializing in the development and commercialization of innovative, first-in-class, oral therapies aimed at lowering low-density lipoprotein cholesterol (LDL-C). The company's flagship product, ETC-1002, is a potent inhibitor of ATP citrate lyase, an enzyme integral to the cholesterol biosynthesis pathway. This pathway also includes HMG-CoA reductase, the enzyme targeted by statins.
Esperion has made significant progress with ETC-1002, completing Phase 1 and Phase 2 clinical trials, and is set to initiate Phase 3 trials. The company's product lineup includes NEXLETOL and NEXLIZET, both of which are oral, once-daily, non-statin medications designed to tackle elevated LDL-C levels. These drugs have recently received expanded FDA approval for cardiovascular risk reduction and are indicated for both primary and secondary prevention patients.
In recent news, Esperion announced that both NEXLETOL and NEXLIZET have received broad new label expansions. These labels now cover cardiovascular risk reduction and expanded LDL-C lowering, either alone or in combination with statins. This approval allows over 70 million patients to access these life-saving drugs, positioning them as the non-statin drugs of choice for cardiovascular risk management.
Esperion is also ramping up its marketing and promotional efforts, enhancing patient support programs, and working with payers to improve patient access. The company is committed to breaking barriers in cardiovascular care and continues to focus on underserved populations, including women and Hispanic/Latinx patients, as demonstrated by their recent CLEAR Outcomes trial.
The company's forward-looking strategy includes ongoing clinical development, financial management, and expansion into new markets. Esperion's dedication to transforming cardiovascular care is evident in its robust pipeline and strategic initiatives aimed at addressing critical unmet medical needs.
Esperion (NASDAQ: ESPR) has completed significant refinancing transactions to strengthen its balance sheet. The company secured a $150 million senior secured term loan facility led by Athyrium Capital Management and HealthCare Royalty, along with issuing $100 million in new convertible notes. These funds will be used to repay $210 million of existing $265 million convertible debt, with $40 million allocated as operating cash.
The new loan bears interest at 9.75% for cash payments or 11.75% if paid in-kind. The new convertible notes mature on June 15, 2030, with a 5.75% annual interest rate and an initial conversion price of $3.06 per share. This restructuring affects 80% of Esperion's existing debt, extending maturity dates by five years or more.
Esperion (NASDAQ: ESPR) has announced a $210 million convertible debt financing through privately negotiated agreements. The company will issue $100 million of 5.75% Convertible Senior Subordinated Notes due 2030, consisting of $57.5 million in new notes plus $153.4 million in cash to exchange $210.1 million of existing 2025 Notes, and $42.5 million in new notes for cash.
The new notes will mature on June 15, 2030, with a 5.75% annual interest rate paid semi-annually. The initial conversion rate is 326.7974 shares per $1,000 principal amount, representing a conversion price of approximately $3.06 per share. The Exchange Transactions will be partially funded through a new $150 Million Senior Secured Term Loan with Athyrium Capital Management.
Esperion Therapeutics (NASDAQ: ESPR) has entered into a licensing agreement with Neopharm Israel for exclusive commercialization rights of NEXLETOL® and NEXLIZET® in Israel. The agreement includes an upfront payment, near-term milestone payments, and tiered royalties on product sales.
Under the agreement terms, Neopharm will receive exclusive commercialization rights in Israel, Gaza, and West Bank. Esperion will receive a one-time upfront cash payment within 30 days of signing, plus an additional payment following marketing approval and inclusion in the National Healthcare Reimbursement Basket. The partnership aims to address cardiovascular disease, which remains a leading cause of death globally.
Esperion (NASDAQ: ESPR) has submitted New Drug Submissions (NDSs) to Health Canada for NEXLETOL and NEXLIZET, once-daily oral non-statin medications for reducing LDL cholesterol and cardiovascular risk. These treatments target adults unable to take recommended statin therapy, with either established cardiovascular disease or high risk for CVD events. According to Canadian health data, approximately 2.6 million Canadian adults live with diagnosed heart disease, with 14 adults dying every hour from the condition.
Esperion (NASDAQ: ESPR) announced that Otsuka Pharmaceutical has submitted a New Drug Application in Japan for bempedoic acid to treat hypercholesterolemia. The Japanese Phase 3 trial, involving 96 patients, demonstrated significant efficacy with a -25.25% change in LDL-C levels compared to -3.46% in the placebo group after 12 weeks. The drug showed consistent safety profile with previous trials and no serious adverse events. This treatment targets patients who have insufficient response to statins or cannot tolerate them. Bempedoic acid works by inhibiting ATP citrate lyase in the liver's cholesterol synthesis pathway and is already marketed in the US and Europe.
Esperion (NASDAQ: ESPR) has announced its participation in the Piper Sandler 36th Annual Healthcare Conference scheduled for Thursday, December 5, 2024, at 12:30 p.m. ET. The event will be webcasted and accessible through Esperion's investor and media section website, with replay available approximately two hours after completion and archived for 90 days.
Esperion focuses on developing innovative medicines for cardiovascular and cardiometabolic diseases, particularly targeting high cholesterol. The company aims to support healthcare providers in reducing LDL-cholesterol levels effectively, addressing the needs of millions of patients whose health requirements are not met by current standards.
Esperion (ESPR) presented new exploratory data from the CLEAR Outcomes trial at the 2024 AHA Scientific Sessions, highlighting significant benefits of NEXLETOL (bempedoic acid). The analysis showed patients with Peripheral Artery Disease (PAD) taking bempedoic acid were 36% less likely to experience major adverse limb events compared to placebo. Additional data revealed that after 3 months, 67% of patients using bempedoic acid and ezetimibe combination achieved LDL-C levels below 100 mg/dL, with 55% maintaining these levels at 12 months.
Esperion (NASDAQ: ESPR) has granted 12,900 restricted stock units (RSUs) to four new employees under its 2017 Inducement Equity Incentive Plan. The RSUs will vest 25% on the one-year anniversary of the recipient's vesting commencement date, with the remaining 75% vesting in twelve equal quarterly installments thereafter. These grants are specifically designed as employment inducements for new hires who were not previously associated with Esperion, in accordance with NASDAQ Listing Rule 5635(c)(4). The vesting is contingent upon continued employment with Esperion.
Esperion (ESPR) reported strong Q3 2024 financial results with total revenue increasing 52% year-over-year to $51.6 million. U.S. net product revenue grew 53% to $31.1 million, driven by retail prescription growth. Total retail prescription equivalents increased 12% and new to brand prescriptions grew 18% from Q2. The company expanded product labels, scaled up commercial team, and strengthened balance sheet by monetizing European royalties. Over 165 million lives now have updated utilization management criteria aligned to new labels across Commercial, Medicare and Medicaid payers. Cash and cash equivalents totaled $144.7 million as of September 30, 2024.
Esperion (NASDAQ: ESPR) has announced its participation in the 2024 Jefferies London Healthcare Conference scheduled for Tuesday, November 19, 2024, at 11:30 a.m. ET. The event will be webcasted live on Esperion's investor and media section website, with replay access available approximately two hours after the call and archived for 90 days.
Esperion focuses on developing innovative medicines for cardiovascular and cardiometabolic diseases, particularly targeting high cholesterol. The company aims to support healthcare providers in reducing LDL-cholesterol levels as effectively as possible, addressing the needs of millions of patients whose health requirements are not met by current standards.
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