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Erasca, Inc. - ERAS STOCK NEWS

Welcome to our dedicated page for Erasca news (Ticker: ERAS), a resource for investors and traders seeking the latest updates and insights on Erasca stock.

Erasca, Inc. (Nasdaq: ERAS) is a clinical-stage precision oncology company dedicated to discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers. Their mission, embodied in their name, is to 'erase cancer'. The company's innovative approach aims to not just treat but potentially cure cancer by targeting and shutting down the RAS/MAPK pathway, which plays a crucial role in many types of cancer.

Erasca’s robust clinical pipeline includes promising drug candidates such as Naporafenib, a pan-RAF inhibitor with first-in-class potential targeting NRASm melanoma and RAS Q61X tissue agnostic solid tumors. The company's other notable candidates include ERAS-007, a highly selective oral ERK1/2 inhibitor, and ERAS-601, an oral SHP2 inhibitor, which target different nodes of the RAS/MAPK pathway. These efforts are supported by recent collaborations with industry giants like Novartis, who are providing crucial compounds like trametinib (MEKINIST®) for combination trials.

On the financial front, Erasca is well-funded with significant investments from both new and existing investors, having recently raised approximately $45 million in a private placement expected to close in April 2024. As of December 2023, the company reported $322 million in cash, cash equivalents, and marketable securities, ensuring a solid runway into the second half of 2026.

Among their latest achievements, Erasca has received FDA Fast Track Designation (FTD) for Naporafenib in combination with trametinib for advanced NRASm melanoma. This designation facilitates accelerated development and review processes, reflecting the potential of their therapies to address unmet medical needs.

The company’s pivotal Phase 3 SEACRAFT-2 trial for Naporafenib in post-immunotherapy settings for NRASm melanoma is slated to begin in the first half of 2024. Additionally, Erasca has announced exciting new partnerships and pipeline enhancements, including in-licensing two preclinical RAS programs, ERAS-0015 and ERAS-4001, to further solidify their leadership in the precision oncology space.

For more up-to-date information on Erasca, Inc., including their latest financial results and key upcoming milestones, visit their official website or recent press releases.

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Erasca, Inc. (Nasdaq: ERAS) announced initial Phase 1/1b data for its ERK1/2 inhibitor ERAS-007 and SHP2 inhibitor ERAS-601, showcasing safe profiles for potential combination therapies in solid tumors. ERAS-801, a CNS-penetrant EGFR inhibitor, shows enhanced anti-tumor activity over osimertinib in preclinical models. New KRAS G12D inhibitors demonstrate significant tumor growth inhibition. The company will present findings at the 34th EORTC-NCI-AACR Symposium in October 2022, with further data expected in 2023, highlighting ongoing advancements in their oncology pipeline.

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Erasca, Inc. (Nasdaq: ERAS), a company dedicated to precision oncology, will participate in the Bank of America Securities Precision Oncology Conference on October 3, 2022, at 3:40 PM ET. CEO Jonathan E. Lim and CFO David M. Chacko will engage in a virtual fireside chat and one-on-one investor meetings. A live webcast will be available, with an archived replay until January 3, 2023. Erasca aims to innovate therapies for RAS/MAPK pathway-driven cancers, leveraging a strong pipeline and expert advisory board to achieve its mission of erasing cancer.

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Erasca, Inc. (Nasdaq: ERAS), a clinical-stage precision oncology company, announced its participation in the Morgan Stanley Global Healthcare Conference. On September 14, 2022, at 12:55 PM ET, CEO Jonathan E. Lim, M.D., and CFO David M. Chacko, M.D., will engage in a fireside chat at Sheraton Hotel, New York. They will also conduct one-on-one investor meetings. A live webcast will be available, with an archived replay accessible until December 14, 2022. Erasca is focused on therapies for RAS/MAPK pathway-driven cancers, aiming to develop innovative cancer treatments.

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Erasca, a clinical-stage precision oncology company, reported promising Phase 1/1b data for its ERK1/2 inhibitor ERAS-007 and SHP2 inhibitor ERAS-601 in treating RAS/MAPK-altered solid tumors. The retrospective analysis revealed that 23% of patients with non-CRC solid tumors and 44% of those with BRAF-driven tumors responded to these agents. Both drugs demonstrated favorable safety profiles, supporting their combination in upcoming trials. The initiation of the ERAS-007 plus ERAS-601 MAPKlamp trial is anticipated in the first half of 2023.

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Erasca, Inc. (Nasdaq: ERAS) will host a virtual research and development day on September 7, 2022, featuring key opinion leader Dr. David Hong from MD Anderson Cancer Center. The event will present preliminary clinical data for Erasca's lead candidates, the ERK1/2 inhibitor ERAS-007 and the SHP2 inhibitor ERAS-601, targeting advanced solid tumors influenced by the RAS/MAPK pathway. Participants can register online for the event, which will include a live Q&A session.

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Erasca, Inc. (Nasdaq: ERAS) has entered a five-year collaboration with The University of Texas MD Anderson Cancer Center to evaluate multiple agents targeting the RAS/MAPK pathway. The partnership's initial focus is on ERAS-007, an ERK1/2 inhibitor, and ERAS-601, a SHP2 inhibitor. These will be combined in the first MAPKlamp approach. Ongoing clinical trials of these agents will target various cancers, including non-small cell lung cancer and gastrointestinal malignancies. The collaboration aims to enhance the clinical development of Erasca's pipeline in addressing significant cancer treatment challenges.

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Erasca, Inc. (Nasdaq: ERAS) reported Q2 2022 financial results, showcasing a cash reserve of $391 million. The company is advancing its clinical programs, expecting initial data for ERAS-007 and ERAS-601 by H2 2022. Notable collaborations include partnerships with Eli Lilly and Harvard Medical School to enhance ERAS-007 and ERAS-601's potential. R&D expenses rose to $27.5 million, driven by clinical trials, while G&A expenses increased to $8.4 million. The net loss for the quarter stands at $35.6 million, or $(0.30) per share.

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Erasca has entered a clinical trial collaboration with Eli Lilly to evaluate ERAS-601, a selective SHP2 inhibitor, in the FLAGSHP-1 trial. This Phase 1/1b trial will assess ERAS-601 combined with Lilly's cetuximab for treating triple wildtype metastatic colorectal cancer and HPV-negative advanced head and neck squamous cell carcinoma. Lilly will provide cetuximab at no cost. The collaboration aims to enhance treatment responses and delay resistance onset in RAS/MAPK driven cancers, addressing significant market needs given the rising case numbers of these malignancies.

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Erasca, Inc. (Nasdaq: ERAS), a clinical-stage precision oncology company focused on therapies for RAS/MAPK pathway-driven cancers, will present at the 2022 Jefferies Healthcare Conference on June 10, 2022, at 8:00 AM ET in New York. CEO Jonathan E. Lim and CFO David M. Chacko will represent the company and participate in one-on-one investor meetings. A live webcast and an archived replay of the presentation will be available online, continuing until September 10, 2022. Erasca’s mission is to erase cancer through innovative therapies targeting the RAS/MAPK pathway.

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Erasca, Inc. (NASDAQ: ERAS) announced a Phase 1b clinical trial for ERAS-007, an ERK1/2 inhibitor, in combination with a KRAS G12C inhibitor, targeting KRAS G12C-driven non-small cell lung cancer (NSCLC) and colorectal cancer (CRC). This trial aims to address RAS/MAPK resistance issues linked to KRAS G12C inhibitors. Preliminary data suggests ERAS-007 may effectively counteract drug resistance mechanisms. The trial will be led by renowned investigators, with additional research planned to assess the safety and efficacy of this combination.

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FAQ

What is the current stock price of Erasca (ERAS)?

The current stock price of Erasca (ERAS) is $2.865 as of November 4, 2024.

What is the market cap of Erasca (ERAS)?

The market cap of Erasca (ERAS) is approximately 795.2M.

What is Erasca, Inc.'s primary focus?

Erasca, Inc. is focused on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers.

What are the key drugs in Erasca’s pipeline?

Key drugs in Erasca's pipeline include Naporafenib, ERAS-007, and ERAS-601 targeting various nodes of the RAS/MAPK pathway.

What recent achievements has Erasca reported?

Erasca has received FDA Fast Track Designation for Naporafenib in combination with trametinib and announced significant collaborations and financial investments.

How is Erasca funded?

Erasca is funded through a combination of private placements and existing investments, with a strong cash position reported at $322 million as of December 2023.

What partnerships has Erasca entered into?

Erasca has partnered with Novartis, among others, to support clinical development of their drug candidates and has in-licensed two preclinical RAS programs.

What is the SEACRAFT-2 trial?

The SEACRAFT-2 trial is a pivotal Phase 3 study evaluating the efficacy of Naporafenib in combination with trametinib for NRAS-mutant melanoma patients post-immunotherapy.

What does FDA Fast Track Designation mean for Erasca?

FDA Fast Track Designation facilitates accelerated development and review processes for Naporafenib in combination with trametinib, aiming to expedite its availability for patients with advanced NRAS-melanoma.

What financial milestones has Erasca achieved recently?

Recently, Erasca secured approximately $45 million in a private placement and reported a strong cash position to fund operations into 2026.

What is the significance of Erasca's mission statement?

Erasca's mission to 'erase cancer' reflects their dedication to creating transformative oncology therapies aimed at not just treating but potentially curing cancer.

How does Erasca's technology target cancer?

Erasca's technology targets the RAS/MAPK pathway, which is critical in many cancers. Their therapies aim to comprehensively shut down this pathway to treat and potentially cure cancer.

Erasca, Inc.

Nasdaq:ERAS

ERAS Rankings

ERAS Stock Data

795.25M
282.50M
12.4%
77.06%
11.93%
Biotechnology
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