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Equillium - EQ STOCK NEWS

Welcome to our dedicated page for Equillium news (Ticker: EQ), a resource for investors and traders seeking the latest updates and insights on Equillium stock.

Equillium Inc. (EQ) is a clinical-stage biotechnology company pioneering therapies for severe autoimmune and inflammatory disorders. This news hub provides investors and stakeholders with timely updates on EQ's scientific advancements, regulatory milestones, and corporate developments.

Access curated press releases and analysis covering key areas including clinical trial results, regulatory communications, research partnerships, and financial performance updates. Our repository simplifies tracking of EQ's novel therapeutic candidates like itolizumab (anti-CD6) and cytokine inhibitors in development.

Bookmark this page for streamlined monitoring of Equillium's progress in addressing conditions such as graft-versus-host disease and lupus nephritis through immunomodulatory approaches. Return regularly for verified updates directly from company filings and authorized sources.

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Equillium announced interim results from the EQUALISE study evaluating itolizumab in lupus nephritis patients. Of the 6 subjects evaluated, 83% achieved a complete or partial response, and 67% attained over 80% reduction in urine protein creatinine ratio (UPCR) by week 28. The treatment showed a favorable safety profile with no serious adverse events. The mean baseline UPCR was notably high at 5.8 g/g, and the study's results point to potential as a competitive therapy in a field where other treatments have fallen short.

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Equillium, Inc. (Nasdaq: EQ) announces the acceptance of its abstract for presentation at ACR Convergence, the American College of Rheumatology’s annual meeting, set for November 10-14, 2022. The abstract, titled 'Urine ALCAM is a Strong Predictor of Lupus Nephritis', highlights urinary soluble ALCAM as a potential biomarker for disease severity in lupus nephritis. Equillium develops novel therapeutics targeting autoimmune disorders, including itolizumab, currently undergoing clinical trials for conditions like lupus nephritis and acute graft-versus-host disease.

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Equillium will acquire Metacrine in an all-stock merger, strengthening its financial position with an additional $33 million in cash upon closing, expected to extend its operational runway into 2024. The acquisition includes the novel drug MET642, a Phase 2-ready FXR agonist for ulcerative colitis. Preston Klassen, CEO of Metacrine, will join Equillium's Board of Directors. The transaction is approved by both companies' boards and aims to enhance Equillium's clinical development efforts and market reach.

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Equillium, a clinical-stage biotechnology company, announces participation in the Wells Fargo Healthcare Conference on September 7 and the H.C. Wainwright Annual Global Investment Conference on September 12. The company will provide insights into its clinical assets and upcoming milestones.

The Wells Fargo event will take place at Encore Boston Harbor at 1:20 PM PT, while the H.C. Wainwright event will be held at Lotte New York Palace Hotel at 12:00 PM PT. Webcast access will be available on Equillium's website.

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Equillium, Inc. (Nasdaq: EQ) reported its Q2 2022 financial results, highlighting a net loss of $14.1 million, or $(0.41) per share, compared to a loss of $9.2 million in Q2 2021. R&D expenses rose to $9.5 million, up from $6.0 million, due to increased clinical development costs. G&A expenses also increased to $4.1 million from $2.9 million. The company is advancing its clinical studies, including initiating Phase 2 trials for EQ101 and EQ102 in alopecia areata and celiac disease, respectively. Cash reserves stood at $57.6 million, sufficient to support operations for at least 12 months.

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Equillium, Inc. (Nasdaq: EQ) announced a presentation at the 3rd Annual Cytokine-Based Drug Development Summit, showcasing its multi-cytokine inhibitor technology. Dr. Stephen Connelly presented data on EQ101, a tri-specific cytokine inhibitor targeting IL-2, IL-9, and IL-15, which has shown promise in treating inflammatory and neoplastic skin diseases. The company plans to initiate Phase 2 and Phase 1 studies for EQ101 and EQ102, respectively, by year's end. This innovative approach may allow for more selective targeting of cytokines compared to traditional JAK inhibitors.

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Equillium, Inc. (Nasdaq: EQ), a clinical-stage biotechnology company, will present at the H.C. Wainwright Global Investment Conference on May 24, 2022, at Fontainebleau Miami Beach Hotel, and at the Jefferies Healthcare Conference on June 8, 2022, at Marriott Marquis, New York City. The company aims to provide updates on its clinical programs and will hold one-on-one meetings. Both presentations will be accessible via webcast, with archived replays available for 90 days. Equillium is focused on developing therapeutics for severe autoimmune disorders.

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Equillium, Inc. (Nasdaq: EQ) has initiated the Phase 3 EQUATOR study of itolizumab for first-line acute graft-versus-host disease (aGVHD). The study aims to enroll up to 200 patients, assessing itolizumab's efficacy against a placebo. Equillium also acquired Bioniz Therapeutics, adding two first-in-class assets to its pipeline. First quarter 2022 financial results showed a net loss of $37.4 million or $(1.17) per share, up from a $9.0 million loss last year due to increased expenses. Cash and equivalents totaled $68.8 million as of March 31, 2022.

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Equillium, Inc. (NASDAQ: EQ) announced that the European Hematology Association has published an abstract on the pivotal Phase 3 EQUATOR study for itolizumab in treating acute graft-versus-host disease (aGVHD). The EQUATOR study is a randomized, double-blind trial involving up to 200 patients, comparing itolizumab with placebo alongside corticosteroids. This study aims to address the lack of approved first-line treatments for aGVHD, with outcomes including complete response rates and safety data. The study follows encouraging results from the Phase 1b EQUATE study.

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Equillium (Nasdaq: EQ) presented new data on its lead drug, itolizumab, at the IMMUNOLOGY2022 conference. The findings suggest that itolizumab effectively reduces CD6 levels on T effector cells, promoting the development of T regulatory cells, which could enhance treatment strategies for autoimmune diseases. The data indicates that targeting the CD6-ALCAM pathway can prevent harmful T cell recruitment into inflamed organs. Currently in Phase 3 trials for acute graft-versus-host disease, itolizumab shows promise for addressing significant unmet medical needs in immunology.

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Equillium

Nasdaq:EQ

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16.88M
22.77M
36.15%
19.42%
1.03%
Biotechnology
Pharmaceutical Preparations
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United States
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