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Enveric Biosciences Agrees to Sell Cancer-Targeting Cannabinoid-Related Intellectual Property

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Enveric Biosciences (NASDAQ: ENVB) announces the sale of a cancer-related patent portfolio to focus on developing neuroplastogenic small-molecule therapeutics for mental health disorders. The company will invest in lead candidates EB-003 and EB-002, targeting depression, anxiety, and addiction disorders. Enveric plans to continue research and development in this area while providing foundational patent protection for the undisclosed purchasers of the divested portfolio.
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The sale of Enveric Biosciences' cancer-related patent portfolio represents a strategic pivot towards prioritizing mental health treatments over oncology assets. This transaction could have immediate financial implications for Enveric, potentially bolstering its cash position, which is critical for a biotech company that is in the development phase. The undisclosed sum might be used to fund ongoing research and trials, reducing the need for further dilutive financing in the short term. However, the long-term impact on the company's revenue streams could be significant, as it foregoes potential future earnings from the sold IP.

Investors should note the strategic focus on EB-003 and EB-002 as an indication of the company's confidence in these assets. The divestiture might be seen as a positive by the market if the proceeds are believed to accelerate the path to commercialization for the mentioned neuroplastogens. However, the lack of transparency regarding the sale amount makes it difficult to assess the full financial impact without additional information.

Enveric's divestment of its oncology-related IP and the focus on the development of neuroplastogens, EB-003 and EB-002, underscores a significant shift in the company's therapeutic direction. Neuroplastogens are compounds that promote neuroplasticity, potentially offering innovative treatments for mental health disorders. The move to concentrate on these molecules suggests a strategic bet on the growing mental health market, which has been gaining attention due to rising global prevalence.

From a medical research perspective, the value of the divested IP in cancer treatment indicates Enveric's ability to generate and monetize research, although the company relinquishes any future involvement in the potential success of these therapies. The decision to sell these assets could be based on an assessment of the competitive landscape, where the company may have identified a greater opportunity and unmet need in mental health.

The pharmaceutical industry is witnessing an increasing interest in psychedelics and related compounds for mental health treatments. Enveric's focus on EB-003 and EB-002, potentially first-in-class and next-generation neuroplastogens, positions the company within this emerging sector. The reference to a 'unique and promising library of novel preclinical compounds' suggests a diverse pipeline that could be attractive to partners or licensees, indicating a proactive business development strategy.

Moreover, the intention to out-license or partner for the development of these compounds could lead to multiple streams of revenue through licensing fees, milestone payments and royalties. The company's ability to generate value from its IP, as demonstrated by the current sale, might reassure investors about its potential to do the same with its mental health portfolio. The success of such strategies, however, will hinge on the clinical success of the compounds and the company's ability to navigate the complex regulatory landscape.

Enveric continues focused investment advancing novel neuroplastogenic molecules for the treatment of mental health disorders

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Enveric Biosciences (NASDAQ: ENVB) (“Enveric” or the “Company”), a biotechnology company dedicated to the development of novel neuroplastogenic small-molecule therapeutics for the treatment of depression, anxiety, and addiction disorders, today announced the company has agreed to sell one of its cancer-related patent portfolios for an undisclosed amount. Enveric plans to continue to focus and invest in the development of its lead candidates EB-003, a first-in-class neuroplastogen designed to eliminate hallucinations, and EB-002, formerly EB-373, a next generation synthetic prodrug of the active metabolite, psilocin.

The patents and applications being sold disclose and claim the synergistic combination of cannabidiol and second therapeutic agents for the treatment of cancer. The divested portfolio includes patents issued in the U.S., Australia, Canada, China, Europe, and Japan, with patent applications pending in Canada, Israel, and Korea. Enveric retains no ownership rights in the divested portfolio, any companies owned by, or to be formed by the recipients.

“We are quite pleased to unlock value from cannabinoid-related IP, which we believe holds considerable value for patients but is no longer central to our core strategy that is focused on the development of EB-003 and EB-002,” said Joseph Tucker, Ph.D., Director and CEO of Enveric. “This transaction will provide the opportunity for Enveric to continue its focused investment in developing neuroplastogens for the treatment of mental health disorders, while providing foundational patent protection for our undisclosed purchasers who we anticipate will pursue research, clinical trials, and commercial development of cannabidiol-based therapies to treat specific types of cancer.”

“Today’s announcement further showcases Enveric’s ability to discover and develop preclinical assets, build strong IP, and generate value both near- and long-term,” added Tucker. “Enveric recently unveiled a unique and promising library of novel preclinical compounds across multiple molecular classes including psilocybin derivatives, psilocybin prodrugs, and mescaline and MDMA derivatives with intentions to out-license and/or partner in the near future.”

For more information about Enveric’s novel preclinical compounds spanning multiple, distinct classes of molecules, please visit: https://www.enveric.com/psybrary.

About Enveric Biosciences

Enveric Biosciences (NASDAQ: ENVB) is a biotechnology company dedicated to the development of novel neuroplastogenic small-molecule therapeutics for the treatment of depression, anxiety, and addiction disorders. Leveraging its unique discovery and development platform, Psybrary™, Enveric has created a robust intellectual property portfolio of New Chemical Entities for specific mental health indications. Enveric’s lead program, EB-003, is a first-in-class approach to the treatment of difficult-to-address mental health disorders designed to promote neuroplasticity without inducing hallucinations in the patient. Enveric is also developing EB-002, formerly EB-373, a next generation synthetic prodrug of the active metabolite, psilocin, being studied as a treatment of psychiatric disorders. Enveric is headquartered in Naples, FL with offices in Cambridge, MA and Calgary, AB Canada. For more information, please visit www.enveric.com.

Forward-Looking Statements

This press release contains forward-looking statements and forward-looking information within the meaning of applicable securities laws. These statements relate to future events or future performance. All statements other than statements of historical fact may be forward-looking statements or information. Generally, forward-looking statements and information may be identified by the use of forward-looking terminology such as “plans,” “expects” or “does not expect,” “proposed,” “is expected,” “budgets,” “scheduled,” “estimates,” “forecasts,” “intends,” “anticipates” or “does not anticipate,” or “believes,” or variations of such words and phrases, or by the use of words or phrases which state that certain actions, events or results may, could, would, or might occur or be achieved. Forward-looking statements may include historical statements and statements regarding beliefs, plans, expectations, or intentions regarding the future and are based on the beliefs of management as well as assumptions made by and information currently available to management. Actual results could differ materially from those contemplated by the forward-looking statements as a result of certain factors, including, but not limited to, the ability of Enveric to: carry out successful clinical programs in Australia; achieve the value creation contemplated by technical developments; avoid delays in planned clinical trials; establish that potential products are efficacious or safe in preclinical or clinical trials; establish or maintain collaborations for the development of therapeutic candidates; obtain appropriate or necessary governmental approvals to market potential products; obtain future funding for product development and working capital on commercially reasonable terms; scale-up manufacture of product candidates; respond to changes in the size and nature of competitors; hire and retain key executives and scientists; secure and enforce legal rights related to Enveric’s products, including patent protection; identify and pursue alternative routes to capture value from its research and development pipeline assets; continue as a going concern; and manage its future growth effectively.

A discussion of these and other factors, including risks and uncertainties with respect to Enveric, is set forth in Enveric’s filings with the Securities and Exchange Commission, including Enveric’s Annual Report on Form 10-K and its Quarterly Reports on Form 10-Q. Enveric disclaims any intention or obligation to revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Investor Relations

Tiberend Strategic Advisors, Inc.

Daniel Kontoh-Boateng

(862) 213-1398

dboateng@tiberend.com

Media Relations

Tiberend Strategic Advisors, Inc.

Casey McDonald

(646) 577-8520

cmcdonald@tiberend.com

Source: Enveric Biosciences

FAQ

What is Enveric Biosciences' ticker symbol?

The ticker symbol for Enveric Biosciences is ENVB.

What are the lead candidates Enveric is focusing on?

Enveric is focusing on developing EB-003, a neuroplastogen to eliminate hallucinations, and EB-002, a synthetic prodrug of psilocin, for mental health disorders.

What is the reason behind Enveric selling its cancer-related patent portfolio?

Enveric is selling the cancer-related patent portfolio to shift focus to developing neuroplastogenic small-molecule therapeutics for mental health disorders.

Which regions are included in the patents and applications being sold by Enveric?

The patents and applications being sold by Enveric include regions such as the U.S., Australia, Canada, China, Europe, and Japan, with pending applications in Canada, Israel, and Korea.

Who is Joseph Tucker and what is his role at Enveric?

Joseph Tucker is the Director and CEO of Enveric Biosciences.

Enveric Biosciences, Inc.

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