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Enlivex Receives Notice of Allowance for Chinese Patent Application Covering Allocetra Immunotherapy

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Enlivex Therapeutics Ltd. (Nasdaq: ENLV) announced that the China National Intellectual Property Administration granted a notice of allowance for a new patent covering AllocetraTM, its macrophage reprogramming immunotherapy. This patent will enhance intellectual property protection in China, covering methods and uses for AllocetraTM. The product aims to reprogram macrophages to their homeostatic state, potentially addressing diseases like sepsis, COVID-19, and solid tumors. Issuance of the patent is expected in the coming months.

Positive
  • Notice of allowance from CNIPA for new patent application covering AllocetraTM enhances IP protection in China.
  • AllocetraTM is positioned as a potential solution for severe diseases with unmet medical needs, like sepsis and COVID-19.
Negative
  • None.

Nes-Ziona, Israel, Feb. 22, 2021 (GLOBE NEWSWIRE) --  Enlivex Therapeutics Ltd., (Nasdaq: ENLV, the “Company”), a clinical-stage macrophage reprogramming immunotherapy company targeting diseased macrophages in patients with sepsis, COVID-19 and solid tumors, today announced that the China National Intellectual Property Administration (CNIPA) issued a notice of allowance for a new patent application (number 201680029277.4) covering AllocetraTM, the Company’s immunotherapy product candidate.  Upon issuance, the new patent will provide added intellectual property protection in China, with respect to methods, uses and pharmaceutical compositions for AllocetraTM. The company expects that this new patent will be issued in China in the coming months.

AllocetraTM is being developed as a universal, off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state. Diseases such as solid cancers, sepsis, COVID-19 and many others reprogram macrophages out of their homeostatic state. These non-homeostatic macrophages contribute significantly to the severity of the respective diseases. By restoring macrophage homeostasis, AllocetraTM has the potential to provide a novel immunotherapeutic mechanism of action for life-threatening clinical indications that are defined as “unmet medical needs”, as a stand-alone therapy or in combination with leading therapeutic agents.

ABOUT ENLIVEX

Enlivex is a clinical stage macrophage reprogramming immunotherapy company developing AllocetraTM, a universal, off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state. Resetting non-homeostatic macrophages into their homeostatic state is critical for immune system rebalancing and resolution of life-threatening conditions. For more information, visit http://www.enlivex.com.

Safe Harbor Statement:  This press release contains forward-looking statements, which may be identified by words such as “expects,” “plans,” “projects,” “will,” “may,” “anticipates,” “believes,” “should,” “would”, “could,” “intends,” “estimates,” “suggests,” “has the potential to” and other words of similar meaning, including statements regarding expected cash balances, market opportunities for the results of current clinical studies and preclinical experiments, the effectiveness of, and market opportunities for, ALLOCETRATM programs. All such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.  Investors are cautioned that forward-looking statements involve risks and uncertainties that may affect Enlivex’s business and prospects, including the risks that Enlivex may not succeed in generating any revenues or developing any commercial products; that the products in development may fail, may not achieve the expected results or effectiveness and/or may not generate data that would support the approval or marketing of these products for the indications being studied or for other indications; that ongoing studies may not continue to show substantial or any activity; and other risks and uncertainties that may cause results to differ materially from those set forth in the forward-looking statements. The results of clinical trials in humans may produce results that differ significantly from the results of clinical and other trials in animals. The results of early-stage trials may differ significantly from the results of more developed, later-stage trials. The development of any products using the ALLOCETRATM product line could also be affected by a number of other factors, including unexpected safety, efficacy or manufacturing issues, additional time requirements for data analyses and decision making, the impact of pharmaceutical industry regulation, the impact of competitive products and pricing and the impact of patents and other proprietary rights held by competitors and other third parties.  In addition to the risk factors described above, investors should consider the economic, competitive, governmental, technological and other factors discussed in Enlivex’s filings with the Securities and Exchange Commission, including in the Company’s most recent Annual Report on Form 20-F filed with the Securities and Exchange Commission.  The forward-looking statements contained in this press release speak only as of the date the statements were made, and we do not undertake any obligation to update forward-looking statements, except as required under applicable law.

ENLIVEX CONTACT                                                                            
Shachar Shlosberger, CFO                                                                    
Enlivex Therapeutics, Ltd.                                                                      
shachar@enlivexpharm.com

INVESTOR RELATIONS CONTACT
Eric Ribner
LifeSci Advisors
eric@lifesciadvisors.com


FAQ

What patent has Enlivex Therapeutics received for AllocetraTM?

Enlivex has received a notice of allowance for a new patent from the China National Intellectual Property Administration covering AllocetraTM.

What is AllocetraTM developed by Enlivex Therapeutics?

AllocetraTM is a universal, off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state.

How does the new patent impact Enlivex's business?

The new patent provides additional intellectual property protection in China, which could enhance market opportunities for AllocetraTM.

What diseases does AllocetraTM target?

AllocetraTM targets severe diseases such as solid tumors, sepsis, and COVID-19.

When is the new patent for AllocetraTM expected to be issued?

The patent is expected to be issued in China in the coming months.

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