STOCK TITAN

ELOXX PHARMACEUTICALS INC - ELOX STOCK NEWS

Welcome to our dedicated page for ELOXX PHARMACEUTICALS news (Ticker: ELOX), a resource for investors and traders seeking the latest updates and insights on ELOXX PHARMACEUTICALS stock.

Eloxx Pharmaceuticals, Inc. (NASDAQ: ELOX) is a clinical-stage biopharmaceutical company focused on the development of novel RNA-modulating drug candidates designed to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are genetic mutations that disrupt protein synthesis, leading to severe genetic disorders. With over 1,800 identified rare diseases caused by these mutations, Eloxx is at the forefront of innovative genetic therapies.

The company's lead product candidate, ELX-02, is a small molecule drug designed to restore production of full-length functional proteins. Currently in Phase 2 clinical development, ELX-02 has shown promise in treating Alport syndrome, a genetic disorder characterized by kidney disease, hearing loss, and eye abnormalities.

Recent advancements include confirmation of ELX-02's disease-modifying potential in Alport syndrome, with positive results from patient biopsies in clinical trials. Eloxx has also submitted an Investigational New Drug (IND) application to the U.S. FDA for ELX-02, aiming to include U.S.-based sites in its pivotal trials.

Additionally, Eloxx is developing ZKN-013, a TURBO-ZM™ based molecule for treating recessive dystrophic epidermolysis bullosa (RDEB) and other genetic conditions. The company has initiated strategic partnerships and aims to begin patient dosing by the end of 2023.

Financially, Eloxx reported a net loss of $3.6 million for Q3 2023 but has shown a decrease in overall R&D and administrative expenses compared to the previous year. The company is focused on improving its liquidity position and raising additional capital to fund operations through 2023 and beyond.

Eloxx continues to leverage its TURBO-ZM™ chemistry platform to develop novel Ribosome Modulating Agents (RMAs) and maintain its commitment to addressing the unmet medical needs of patients with rare genetic disorders. For the latest updates and detailed information, visit www.eloxxpharma.com.

Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) announced the publication of two scientific manuscripts in leading journals. The first manuscript reviews ELX-02's development for treating nonsense-mediated genetic diseases, authored by Professor Eitan Kerem, supporting ongoing Phase 2 trials. The second highlights the functional activity of small molecule compounds in a mouse model, showcasing their potential in treating inherited retinal disorders and systemic diseases like cystic fibrosis. Eloxx is advancing IND-enabling preclinical studies for its ERSG compounds targeting various genetic disorders.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-2.8%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) has presented significant data from two abstracts at the North American Cystic Fibrosis Virtual Conference. The research focuses on ELX-02, a drug aimed at treating cystic fibrosis through the read-through of premature stop codons. Notably, results indicate ELX-02's selective action without affecting native stop codons. The company is advancing Phase 2 clinical trials across Europe, Israel, and the U.S., eager to report top-line data from these trials soon.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
8.21%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) plans to release its Q3 2020 financial and operational results on November 5, 2020. A conference call and webcast will be held at 4:30 p.m. ET to provide updates. The company specializes in developing innovative therapeutics targeting cystic fibrosis and other diseases caused by nonsense mutations. Its lead candidate, ELX-02, is designed to restore production of functional proteins. Eloxx also has preclinical programs addressing kidney and ocular genetic disorders.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
2.43%
Tags
conferences earnings
Rhea-AI Summary

Eloxx Pharmaceuticals, a clinical-stage biopharmaceutical company, announced the appointment of Professor Eitan Kerem as Senior Consultant. Dr. Kerem will advise on the company's cystic fibrosis program, focusing on strategic leadership and medical safety review. Eloxx is advancing its Phase 2 clinical trial for ELX-02, aimed at treating cystic fibrosis caused by nonsense mutations. Dr. Kerem's experience will be crucial as Eloxx approaches significant milestones in the trial. The company emphasizes the urgent need for therapies in this area as they prepare to report top-line results.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
5.07%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) has announced the upcoming presentation of two abstracts at the North American Cystic Fibrosis Conference (NACFC) starting October 7, 2020. The abstracts will showcase preclinical study results on the drug ELX-02, which targets cystic fibrosis caused by nonsense mutations. CEO Gregory Williams emphasized ELX-02’s effectiveness in restoring CFTR production in patient-derived organoids. The posters will be available to registered attendees and published in Pediatric Pulmonology.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-1.76%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) has resumed enrollment in its Phase 2 clinical trial for ELX-02, aimed at treating cystic fibrosis, in the U.S., following a temporary pause due to COVID-19. This follows similar resumption in Europe and Israel on June 17, 2020. CEO Dr. Gregory Williams emphasized the company's commitment to completing the trial and reporting data promptly. ELX-02 targets diseases caused by premature stop codons and is still in early clinical development. Further details can be found on the company's website.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
8.09%
Tags
clinical trial covid-19
Rhea-AI Summary

Eloxx Pharmaceuticals has resumed enrollment in its Phase 2 clinical trial for ELX-02 in cystic fibrosis in Europe and Israel after a COVID-19 pause. The FDA granted orphan drug designation for ELX-02, providing benefits like seven years of exclusivity upon approval. With cash reserves of $37.1 million as of June 30, 2020, the company has funding through 2021. Eloxx is advancing preclinical studies in autosomal dominant polycystic kidney disease and retinal disorders. The completion of Phase 2 trials for ELX-02 remains a priority, with data expected to significantly affect the company's valuation.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-6.93%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) has received orphan drug designation from the FDA for its product ELX-02, aimed at treating cystic fibrosis. This designation supports the development of treatments for rare diseases impacting fewer than 200,000 U.S. patients. Benefits include seven years of market exclusivity post-approval and exemption from FDA application fees. Eloxx has resumed Phase 2 clinical trials in Israel and Europe, while U.S. trials remain paused due to COVID-19. CEO Gregory Williams highlighted this as a potential value inflection point for the company.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
3.64%
Tags
none
-
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) announced that CEO Dr. Gregory Williams will present and hold one-on-one meetings at the 40th Annual Canaccord Genuity Virtual Growth Conference on August 13, 2020, at 4:00 PM ET. The presentation will cover Eloxx's development of novel therapeutics aimed at treating cystic fibrosis and other diseases caused by nonsense mutations. Investors can access the live webcast through the company’s website, with a replay available afterward. Eloxx focuses on developing drugs to address rare genetic disorders.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-4.04%
Tags
conferences
Rhea-AI Summary

Eloxx Pharmaceuticals (NASDAQ: ELOX) announced it will release its second quarter 2020 financial results on August 6, 2020. The conference call is scheduled for 2:00 p.m. ET and will be accessible via a live webcast on the company’s website. Eloxx specializes in developing RNA-modulating drug candidates aimed at treating cystic fibrosis and other diseases caused by nonsense mutations in protein synthesis. Their lead candidate, ELX-02, is still in early clinical development. The company's recent efforts have also included a new program focused on rare ocular genetic disorders.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
1.01%
Tags
conferences earnings

FAQ

What is the current stock price of ELOXX PHARMACEUTICALS (ELOX)?

The current stock price of ELOXX PHARMACEUTICALS (ELOX) is $0.000001 as of December 20, 2024.

What is the market cap of ELOXX PHARMACEUTICALS (ELOX)?

The market cap of ELOXX PHARMACEUTICALS (ELOX) is approximately 314.0.

What is Eloxx Pharmaceuticals' primary focus?

Eloxx Pharmaceuticals focuses on developing RNA-modulating drug candidates to treat rare and ultra-rare premature stop codon diseases.

What is ELX-02?

ELX-02 is Eloxx's lead product candidate, a small molecule drug designed to restore production of full-length functional proteins, currently in Phase 2 clinical development for treating Alport syndrome.

What is the significance of premature stop codons?

Premature stop codons are genetic mutations that disrupt protein synthesis, leading to severe genetic disorders. Eloxx targets these mutations to restore protein production.

What are the recent advancements with ELX-02?

ELX-02 has shown disease-modifying potential in clinical trials for Alport syndrome, with positive results in patient biopsies and an IND submission to the FDA for further trials.

What is ZKN-013?

ZKN-013 is a TURBO-ZM™ based molecule under development by Eloxx for treating recessive dystrophic epidermolysis bullosa (RDEB) and other genetic conditions.

How is Eloxx Pharmaceuticals performing financially?

Eloxx reported a net loss of $3.6 million for Q3 2023, with decreased R&D and administrative expenses compared to the previous year. The company is focused on improving liquidity and raising additional capital.

What is the TURBO-ZM™ platform?

The TURBO-ZM™ platform is Eloxx's innovative chemistry technology platform used to develop novel Ribosome Modulating Agents (RMAs) for treating genetic disorders.

What are the challenges Eloxx Pharmaceuticals is facing?

Eloxx is focused on improving its liquidity position, raising additional capital, and maintaining compliance with Nasdaq listing requirements.

What are Eloxx's future plans?

Eloxx plans to advance ELX-02 into pivotal trials for Alport syndrome, initiate clinical studies for ZKN-013, and continue leveraging their TURBO-ZM™ platform for new therapies.

Where can I find more information about Eloxx Pharmaceuticals?

For more information, visit Eloxx Pharmaceuticals' official website at www.eloxxpharma.com.

ELOXX PHARMACEUTICALS INC

Nasdaq:ELOX

ELOX Rankings

ELOX Stock Data

314
2.81M
5.98%
19.59%
0.7%
Biotechnology
Healthcare
Link
United States of America
Watertown