Dyne Therapeutics Announces Chief Business Officer and Chief Scientific Officer Appointments

Rhea-AI Summary

Dyne Therapeutics (Nasdaq: DYN) has announced key leadership appointments to strengthen its executive team ahead of potential product launches in 2027. Vikram Ranade, PhD, has been appointed as Chief Business Officer to lead business development and strategic partnerships, bringing experience from Tessera Therapeutics where he helped secure over $600 million in equity financing.

Ranjan Batra, PhD, will join as Chief Scientific Officer on April 28, 2025, bringing expertise in RNA biology and therapeutics from Lexeo Therapeutics. Additionally, Oxana Beskrovnaya, PhD, will transition to Chief Innovation Officer to drive the company's FORCE™ platform development.

These appointments align with Dyne's preparation for launching two medicines in myotonic dystrophy type 1 and Duchenne muscular dystrophy in 2027, focusing on delivering therapies for genetically driven neuromuscular diseases.

Positive

• Planned launch of two medicines in 2027 indicates advanced pipeline progression
• Strategic executive appointments strengthen leadership team ahead of commercialization
• New CBO brings track record of securing significant financing ($600M+)
• New CSO brings expertise in RNA biology and therapeutics relevant to core disease targets

Negative

• Two-year wait until potential product launches indicates no immediate revenue generation
• Multiple simultaneous leadership changes may cause temporary organizational disruption

- Vikram Ranade, PhD, appointed as chief business officer -

- Ranjan Batra, PhD, appointed as chief scientific officer -

- Oxana Beskrovnaya, PhD, transitioning to chief innovation officer -

WALTHAM, Mass., April 15, 2025 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (Nasdaq: DYN), a clinical-stage company focused on advancing life-transforming therapeutics for people living with genetically driven neuromuscular diseases, today announced the appointments of Vikram (Vik) Ranade, PhD, as chief business officer (CBO) and Ranjan (Ron) Batra, PhD, as chief scientific officer (CSO) of Dyne. Dr. Ranade will lead business development, corporate strategy and strategic partnerships to support the company’s late-stage clinical and commercialization plans. Dr. Batra will lead the company’s research strategy, pipeline development and activities supporting clinical development. Effective April 28, 2025, Oxana Beskrovnaya, PhD, will transition from CSO to chief innovation officer (CIO) responsible for driving Dyne’s comprehensive innovation strategy to maximize the value of its FORCE™ platform and further enable the company’s long-term success.

“I am excited to welcome Vik and Ron to our leadership team. Vik’s experience in business development and corporate strategy will be invaluable as we prepare for the potential launches of two medicines in 2027 in myotonic dystrophy type 1 and Duchenne muscular dystrophy. Our incoming CSO, Ron, will play a key role in advancing our pipeline and elucidating the power of the FORCE platform to deliver functional improvement in the clinic,” said John Cox, president and chief executive officer of Dyne. “With the addition of Vik, Ron and our CFO, Erick Lucera, as well as Oxana in her new role as CIO, we are well positioned to drive the business, deliver therapies that bring functional improvement to patients and create significant shareholder value through our clinical programs, pipeline and unique platform.”

• Dr. Ranade joins Dyne, effective immediately, from Tessera Therapeutics, where he was senior vice president of corporate development, leading strategy and business development, and was member of the executive team. During more than five years at Tessera he also played a key role in equity financings totaling more than $600 million. Previously, he worked in McKinsey & Company’s healthcare practice, advising biopharmaceutical and biotechnology companies on strategy, M&A and R&D. He led diligence on completed deals with an aggregate transaction value of more than $15 billion and advised on clinical strategy for more than 20 programs. Dr. Ranade also co-led McKinsey’s Center for Asset Optimization, which focuses on clinical-stage asset development strategy. Dr. Ranade holds a PhD in Genetics and Development from Columbia University and a BS in biochemistry from Brandeis University, where he earned highest honors for his research on DNA damage repair pathways.
  

“I am thrilled to welcome Ron as our new scientific leader. He brings outstanding scientific expertise and the required peer network and passion to continue to expand Dyne’s pipeline of potentially transformative therapies,” said Dr. Beskrovnaya. “In my new role, I look forward to working with our strong leadership team and leveraging our world-class expertise in TfR1 delivery to pioneer and accelerate new therapeutic applications.”

• Dr. Batra joins Dyne, effective April 28, 2025, from Lexeo Therapeutics, where he was vice president of research and translation. A leading expert in RNA biology and therapeutics, he has developed cutting-edge treatments for genetic diseases. Previously, Dr. Batra served as a senior vice president of R&D at LocanaBio, advancing RNA-targeted therapies for rare disorders including Duchenne muscular dystrophy and myotonic dystrophy. Prior to LocanaBio, he worked at Verily Life Sciences and conducted pioneering research at UC San Diego and the University of Florida with more than 35 publications and patents. Dr. Batra earned a PhD in genetics from the University of Florida, where he studied RNA biology and gene therapy for neuromuscular diseases.
  

About Dyne Therapeutics

Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Forward-Looking Statements

This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release, including statements regarding Dyne’s strategy, future operations, prospects and plans, objectives of management, the potential of the FORCE platform, the potential of DYNE-101 and DYNE-251, and expectations regarding the timing of commercial launches constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “objective,” “ongoing,” “plan,” “predict,” “project,” “potential,” “should,” or “would,” or the negative of these terms, or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Dyne may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including: uncertainties inherent in the identification and development of product candidates, including the initiation and completion of preclinical studies and clinical trials; uncertainties as to the availability and timing of results from preclinical studies and clinical trials; the timing of and Dyne’s ability to enroll patients in clinical trials; whether results from preclinical studies and data from clinical trials will be predictive of the final results of the clinical trials or other trials; whether data from clinical trials will support submission for regulatory approvals; uncertainties as to the FDA’s and other regulatory authorities’ interpretation of the data from Dyne's clinical trials and acceptance of Dyne's clinical programs and as to the regulatory approval process for Dyne’s product candidates; whether Dyne’s cash resources will be sufficient to fund its foreseeable and unforeseeable operating expenses and capital expenditure requirements; as well as the risks and uncertainties identified in Dyne’s filings with the Securities and Exchange Commission (SEC), including the Company’s most recent Form 10-K and in subsequent filings Dyne may make with the SEC. In addition, the forward-looking statements included in this press release represent Dyne’s views as of the date of this press release. Dyne anticipates that subsequent events and developments will cause its views to change. However, while Dyne may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Dyne’s views as of any date subsequent to the date of this press release.

Contacts:

Investors
Mia Tobias
ir@dyne-tx.com
781-317-0353

Media
Stacy Nartker
snartker@dyne-tx.com
781-317-1938

Photos accompanying this announcement are available at:

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https://www.globenewswire.com/NewsRoom/AttachmentNg/9ebc562f-504a-4469-a1f7-5d1f919c55fe

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FAQ

When is Dyne Therapeutics (DYN) planning to launch its new medicines?

Dyne Therapeutics plans to launch two medicines in 2027, targeting myotonic dystrophy type 1 and Duchenne muscular dystrophy.

Who are the new executive appointments at Dyne Therapeutics (DYN)?

Vikram Ranade as Chief Business Officer, Ranjan Batra as Chief Scientific Officer (effective April 28, 2025), and Oxana Beskrovnaya transitioning to Chief Innovation Officer.

What is the focus of Dyne Therapeutics' (DYN) therapeutic development?

Dyne focuses on developing life-transforming therapeutics for people with genetically driven neuromuscular diseases using their FORCE™ platform.

What is Vikram Ranade's track record in financing at his previous company before joining DYN?

At Tessera Therapeutics, Ranade played a key role in securing equity financings totaling more than $600 million.