New Data Validates Blood Volume Analysis Guided-Care, Improves Survival in Patients with Advanced Heart Failure Supported with Left Ventricular Assist Device

Rhea-AI Summary

Daxor Corporation (Nasdaq: DXR) has presented new data at the ISHLT Annual Meeting showcasing the efficacy of its BVA-100 blood test in enhancing survival rates for advanced heart failure patients using LVADs. The study revealed that 91% of patients with LVADs exhibited abnormal blood volume, indicating the test's critical role in patient management. With a 98% accuracy rate, the BVA-100 test helps identify derangements in blood volume, potentially improving patient outcomes. Daxor emphasizes its commitment to advancing healthcare through blood volume analysis technology.

Positive

• BVA-100 test shows potential to improve survival rates in LVAD patients.
• Study found that 75% of patients exhibited plasma volume abnormalities, highlighting the test's importance.
• Company reported over 100 peer-reviewed studies supporting BVA-100's effectiveness in reducing mortality and hospital readmissions.

Negative

• 91% of patients had abnormal blood volume, indicating a significant undiagnosed issue.
• 54% of patients had a significant red blood cell deficit, which could impact treatment outcomes.

Study Presented at the International Society for Heart and Lung Transplant 42^nd Annual Meeting and Scientific Sessions 2022

Oak Ridge, TN, May 02, 2022 (GLOBE NEWSWIRE) -- Daxor Corporation (Nasdaq: DXR), the global leader in blood volume measurement technology, announces new data validating the benefits of the Company’s BVA-100 blood test (BVA) in improving survival for advanced heart failure patients with left ventricular assist device (LVAD). These data were presented at the International Society for Heart and Lung Transplant (ISHLT) Annual Meeting and Scientific Sessions – which brought together the world’s leading experts in heart and lung transplant, held from April 27-30^th, in Boston, MA.

Implantable left ventricular assist devices have dramatically changed the face of advanced heart failure treatment and constitute a $350M annual market in the U.S. Patients suffering from persistent blood volume derangements have lower survival and decreased LVAD functionality but absent a BVA test go largely undiagnosed.

Lead study author Dmitry M. Yaranov, M.D., Baptist Heart Institute, Memphis, TN stated, “Significant derangement of blood volume persists in ambulatory patients with LVAD”, noting that 91% of patients studied had an abnormal blood volume. He concluded, “BVA and its individualized, unique metrics is a valuable test when used in patients with LVAD. Measurement and treatment of derangements of intravascular volumes likely will improve performance and survival of patients and devices.”

The study titled, “Intravascular Volume Derangement and Value of Blood Volume Analysis In Stable Ambulatory Patients with Advanced Heart Failure Supported with Left Ventricular Assist Device,” described variations in blood volume status (total blood and red blood cell volume) in 45 stable ambulatory patients with LVAD. Blood volume parameters were measured with Daxor’s BVA-100 diagnostic blood test, which is a safe, 98% accurate, and objective test to directly quantify blood volume and composition.

The study concluded that plasma volume abnormality was found in 75% of patients. The data revealed that only 9% of these patients had normal blood volume results; 54% had significant red blood cell deficit and 12% had red blood cell excess. It was assumed from a clinical perspective and from LVAD device monitoring that there was no awareness or suspicion of significant alterations in intravascular volumes.

“This research reinforces that a volume-guided approach in treating advanced heart failure with the BVA-100 blood test is paramount in informing the correct treatment strategies -- resulting in significantly better clinical benefits and survival for patients,” said Michael Feldschuh, President, and CEO of Daxor Corporation. “More than 100 published peer-reviewed studies have proven our BVA-100 blood test has shown substantial improvements in mortality reduction, hospital readmission, and reduced costs through its unique accuracy and efficacy. We remain committed as the global leader of BVA technology and anticipate our next generation devices coming to market will accelerate our growing adoption even further in the near future.”

About Daxor Corporation

Daxor Corporation (Nasdaq: DXR), is the global leader in blood volume measurement technology focused on blood volume testing innovation. We developed and market the BVA-100^® (Blood Volume Analyzer), the first diagnostic blood test cleared by the FDA to provide safe, accurate, objective quantification of blood volume status and composition compared to patient-specific norms. Over 60,000+ tests have been performed at leading hospital centers across the U.S., enhancing hospital performance metrics in a broad range of surgical and medical conditions, including significantly reducing mortality and readmissions in heart failure and critical care. Daxor has several ongoing multicenter trials in the areas of COVID-19 and heart failure treatment with support from the NIH and is under contract developing analyzers to improve combat casualty care with the U.S. Department of Defense. Daxor's mission is to advance healthcare by enabling optimal fluid management with blood volume analysis. Daxor’s vision is optimal blood volume for all. For more information, please visit our website at Daxor.com.

Forward-Looking Statements
Certain statements in this release may include forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including without limitation, statements regarding the impact of hiring sales staff and expansion of our distribution channels. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this release, including, without limitation, those risk associated with our post-market clinical data collection activities, benefits of our products to patients, our expectations with respect to product development and commercialization efforts, our ability to increase market and physician acceptance of our products, potentially competitive product offerings, intellectual property protection, FDA regulatory actions, our ability to integrate acquired businesses, our expectations regarding anticipated synergies with and benefits from acquired businesses, and additional other risks and uncertainties described in our filings with the SEC. Forward-looking statements speak only as of the date when made. Daxor does not assume any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Relations Contact:
Bret Shapiro
Sr. Managing Partner, CORE IR
1-516-222-2560
brets@coreir.com

FAQ

What does the recent study by Daxor Corporation reveal about the BVA-100 test?

The study indicates that the BVA-100 blood test can significantly improve survival rates for patients with left ventricular assist devices (LVADs) by identifying abnormal blood volume.

How accurate is the BVA-100 blood test?

The BVA-100 blood test boasts a 98% accuracy rate in quantifying blood volume and composition.

What was the focus of the research presented at the ISHLT Annual Meeting?

The research focused on intravascular volume derangement in stable ambulatory patients with advanced heart failure supported by LVADs.

What market does Daxor Corporation operate in?

Daxor Corporation operates within the $350 million U.S. market for advanced heart failure treatment.

How many studies support the effectiveness of the BVA-100 test?

Over 100 published peer-reviewed studies back the efficacy of the BVA-100 test in reducing mortality and hospital readmissions.