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Precision BioSciences to Present Preclinical In Vivo Gene Editing Research at Upcoming American Society of Gene & Cell Therapy 25th Annual Meeting

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Precision BioSciences (Nasdaq: DTIL) announced that four abstracts, including a collaborative research project, were accepted for presentation at the American Society of Gene & Cell Therapy (ASGCT) annual meeting from May 16-19, 2022, in Washington, D.C..

The presentations will focus on advancements in ARCUS® gene editing therapies. Highlights include oral presentations on targeting Hepatitis B and gene targeting in macaques, as well as poster presentations on optimizing ARCUS nucleases for treating specific genetic diseases.

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- Accepted abstracts to be presented as oral presentations and posters highlight preclinical development progress for ARCUS® gene editing therapies

DURHAM, N.C.--(BUSINESS WIRE)-- Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS®-based ex vivo allogeneic CAR T and in vivo gene editing therapies, today announced that four abstracts, including one from a research and license collaboration, were accepted by the American Society of Gene & Cell Therapy (ASGCT) and will be presented as posters and oral presentations at the upcoming annual meeting on May 16-19, 2022 at the Walter E. Washington Convention Center in Washington, D.C.

Details for the poster and oral presentations can be accessed on the ASGCT website at https://annualmeeting.asgct.org/abstracts.

Oral Presentations:

Title: Targeting the Hepatitis B cccDNA with a Sequence-Specific ARCUS Nuclease to Eliminate Hepatitis B Virus In Vivo
Date and Time: Tuesday, May 17, 2022, 3:45 PM4:00 PM
Session Title: Gene Editing in Cancer and Complex Diseases
Location: Hall E
Abstract #: 447

Title: AAV-Meganuclease-Mediated Gene Targeting Achieves Efficient and Sustained Transduction in Newborn and Infant Macaque Liver1
Date and Time: Wednesday, May 18, 2022, 3:00 PM3:15 PM
Session Title: Presidential Symposium and Presentation of Top Abstracts
Location: Hall E
Abstract #: 811

Poster Presentations:

Title: Optimization of Hydroxyacid Oxidase 1 (HAO1) Targeting ARCUS Nucleases for the Treatment of Primary Hyperoxaluria Type 1 (PH1)
Date and Time: Monday, May 16, 2022, 5:30 PM - 6:30 PM
Session Title: Metabolic, Storage, Endocrine, Liver and Gastrointestinal Diseases I
Location & Poster Board Number: Hall D, M-120
Abstract #: 239

Title: ARCUS Gene Editing to Eliminate MELAS-associated m.3243A>G Mutant Mitochondrial DNA
Date and Time: Tuesday, May 17, 2022, 5:30 PM - 6:30 PM
Session Title: Gene Targeting and Gene Correction II
Location & Poster Board Number: Hall D, Tu-66
Abstract #: 561

1 University of Pennsylvania’s Gene Therapy Program presentation sponsored by iECURE.

About Precision BioSciences, Inc.

Precision BioSciences, Inc. is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS® genome editing platform. ARCUS is a highly precise and versatile genome editing platform that was designed with therapeutic safety, delivery, and control in mind. Using ARCUS, the Company’s pipeline consists of multiple ex vivo “off-the-shelf” CAR T immunotherapy clinical candidates and several in vivo gene editing candidates designed to cure genetic and infectious diseases where no adequate treatments exist. For more information about Precision BioSciences, please visit www.precisionbiosciences.com.

Investor Contact:

Mei Burris

Director, Investor Relations and Finance

Mei.Burris@precisionbiosciences.com

Media Contact:

Maurissa Messier

Senior Director, Corporate Communications

Maurissa.Messier@precisionbiosciences.com

Source: Precision BioSciences, Inc.

FAQ

What abstracts will Precision BioSciences present at ASGCT in 2022?

Precision BioSciences will present four abstracts on ARCUS® gene editing therapies at ASGCT's annual meeting from May 16-19, 2022.

When is the ASGCT annual meeting where DTIL will present?

The ASGCT annual meeting will take place from May 16-19, 2022.

Where is the ASGCT annual meeting being held?

The annual meeting will be held at the Walter E. Washington Convention Center in Washington, D.C.

What is the focus of the oral presentations by DTIL at ASGCT?

The oral presentations will focus on gene editing therapies targeting Hepatitis B and other genetic diseases.

What is the significance of the presentations for DTIL?

The presentations showcase the progress of DTIL's ARCUS® gene editing platform and its applications in treating genetic and infectious diseases.

Precision BioSciences, Inc.

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