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Precision Biosciences - DTIL STOCK NEWS

Welcome to our dedicated page for Precision Biosciences news (Ticker: DTIL), a resource for investors and traders seeking the latest updates and insights on Precision Biosciences stock.

Overview

Precision Biosciences, Inc. (DTIL) is a biotechnology firm headquartered in Durham, North Carolina, that specializes in genome editing technologies. At its core, the company focuses on revolutionizing the treatment of human diseases while also addressing challenges in food and agriculture. The company harnesses its proprietary ARCUS genome editing platform, employing advanced gene editing techniques that differentiate it from traditional methods. Key industry keywords such as genome editing, gene therapy, and biotechnological innovation underscore its foundational commitment to science and therapeutic development.

The ARCUS Genome Editing Platform

The ARCUS platform is the cornerstone of Precision Biosciences' technology. This innovative system is based on a unique enzyme that is both compact and versatile. Its small size permits efficient delivery using both viral and non-viral gene delivery methods, allowing it to access a broad spectrum of cells and tissues. This flexibility not only enhances the precision of the genome editing process but also minimizes potential off-target effects, making the platform a promising alternative to conventional gene editing tools. Moreover, the ARCUS platform is engineered to address complex genetic disorders and provide novel pathways for therapeutic intervention.

Applications & Pipeline

Precision Biosciences strategically applies its expertise in genome editing to multiple dimensions of healthcare and agriculture. In the therapeutic realm, the company is developing a diversified pipeline of product candidates aimed at treating complex human diseases. The focus on precision and efficiency in gene editing allows for the potential correction of genetic anomalies that underlie many serious conditions. Beyond human therapeutics, the ARCUS platform has been explored as a tool in the agricultural sector, offering solutions that may lead to improved crop resilience and productivity. This dual application underscores the company’s broad technological impact and its commitment to addressing global challenges in both health and food security.

Competitive Landscape & Differentiators

In a market that includes several players in the genome editing arena, Precision Biosciences differentiates itself through the unique characteristics of its ARCUS platform. Unlike traditional gene editing systems, the ARCUS enzyme's reduced size allows for a more comprehensive range of cellular targets and a potentially safer profile when integrated into gene therapy applications. The company’s comprehensive approach, which integrates discovery, development, and application, positions it distinctly in a competitive landscape where precision and adaptability are critical for success.

Operational Strategy & Research Excellence

Precision Biosciences operates under a model of continuous innovation and rigorous scientific inquiry. The company’s R&D efforts are deeply rooted in understanding the delicate nuances of genomic medicine and the technical challenges associated with effective gene editing. By leveraging both in-house talent and strategic academic collaborations, the company remains at the forefront of technological advances. Investment in versatile delivery methodologies further enhances the ARCUS system, with researchers constantly working to expand its capabilities in editing precision and efficacy. The blend of scientific rigor and operational agility is apparent in the company’s methodical approach to addressing core biological challenges.

Market Position & Industry Impact

Precision Biosciences occupies a notable niche within the biotechnology sector. Its emphasis on genome editing not only contributes to advancements in targeted therapeutics but also establishes a framework for potential revolutionary changes in agriculture. By integrating robust scientific research with scalable technological applications, the company fosters an environment where complex genetic challenges can be mitigated. The ARCUS platform, with its innovative design, is central to the company’s vision of harnessing precise genetic modifications to drive efficiency in both healthcare and agricultural production. The comprehensive approach taken by Precision Biosciences helps demystify the often intricate subject of gene editing and makes it accessible to a broader audience including investors and scientific peers.

Intellectual Property & Technological Edge

A critical factor underpinning the company's success is its strong portfolio of intellectual property associated with the ARCUS platform. This collection of patents and proprietary methodologies provides a competitive mooring that shields the company’s innovations and fosters a secure environment for future collaborative efforts within the industry. By investing heavily in the protection and expansion of its technological assets, Precision Biosciences reinforces its expertise and demonstrates an unwavering commitment to advancing genome editing science responsibly and effectively.

Global Collaborations & Industry Partnerships

Recognizing the value of strategic alliances, Precision Biosciences engages in numerous collaborations with academic institutions, research centers, and industry partners. These partnerships play an essential role in validating the ARCUS platform’s efficacy and expanding its application across diverse fields. Such cooperative efforts not only accelerate innovation but also help integrate the company’s technological advancements into broader scientific efforts around the world. This interconnected approach underlines the company’s commitment to transparency and the pursuit of excellence in scientific discovery, embodying a holistic view that benefits both the research community and end users.

Scientific Rigor & Regulatory Considerations

Operating in a highly regulated industry, Precision Biosciences emphasizes scientific rigor and a cautious approach to translating laboratory innovations into viable therapeutic solutions. The company upholds stringent quality controls and comprehensive validation processes that help ensure the safety and effectiveness of its genome editing interventions. By adhering to established regulatory frameworks and continuously refining its methodologies, the company reinforces its position as a scientifically sound enterprise. This detailed, methodical approach is integral to earning the confidence of both the scientific community and regulatory bodies.

Conclusion

In summary, Precision Biosciences, Inc. stands out as a formidable entity in the biotechnology sector through its innovative ARCUS genome editing platform. The company’s versatile technology, coupled with its expansive application in both healthcare and agriculture, forms the backbone of a distribution model that is thoughtful and scientifically rigorous. By continuously pushing the frontiers of gene editing, the company demonstrates a robust grasp of future challenges and solutions in genomic medicine and agricultural innovation. Investors and industry observers view Precision Biosciences as a compelling case study in how focused technical innovations, when coupled with a comprehensive business strategy, can effect meaningful change in addressing genetic disorders and global food security issues. The commitment to research excellence, coupled with strategic collaborations and a deep understanding of market dynamics, makes the company a noteworthy player in the evolving landscape of gene editing and biotechnology.

Rhea-AI Summary

Precision BioSciences (Nasdaq: DTIL), a clinical-stage biotechnology company, announced its participation in two virtual investor conferences on October 5, 2020. The conferences include the Chardan 4th Annual Genetic Medicines Conference, scheduled for 8:30 AM ET, and the Jefferies Cell Therapy Summit, starting at 5:30 PM ET. Live webcasts will be accessible on the company’s website, with archived replays available for 30 days post-event. Precision BioSciences utilizes its ARCUS genome editing platform to develop innovative therapies for genetic and infectious diseases.

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Precision BioSciences (Nasdaq: DTIL) announced a clinical trial collaboration with SpringWorks Therapeutics (Nasdaq: SWTX) to evaluate PBCAR269A, an allogeneic CAR T cell therapy targeting BCMA, in combination with nirogacestat, a gamma secretase inhibitor. The trial aims to improve outcomes in relapsed or refractory multiple myeloma patients and is set to commence in early 2021. Precision will cover all development costs, with the FDA granting Fast Track Designation to PBCAR269A. This collaboration seeks to enhance the efficacy of BCMA-targeted therapies through combined treatment strategies.

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Precision BioSciences (Nasdaq: DTIL) expands its CAR T development agreement with Servier, adding two hematological and two solid tumor targets to its pipeline. This collaboration enhances the ongoing development of PBCAR0191, targeting CD19 in treating non-Hodgkin lymphoma and B-cell precursor acute lymphoblastic leukemia. Precision aims to utilize its ARCUS genome editing platform for early-stage research, with potential milestone payments expected in 2020 and 2021. The partnership aims to innovate 'off-the-shelf' CAR T therapies for broader cancer treatment applications.

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Precision BioSciences has received Fast Track Designation from the FDA for its CAR T cell therapy, PBCAR269A, aimed at treating relapsed/refractory multiple myeloma. This designation follows the previously granted Orphan Drug Designation, expediting the clinical development process. PBCAR269A is undergoing a Phase 1/2a trial, with a focus on assessing safety and efficacy at escalating doses. The company leverages its proprietary ARCUS technology to optimize CAR T therapies, ultimately aiming to make treatments more accessible for patients.

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Precision BioSciences (Nasdaq: DTIL) announced its participation in three upcoming investor conferences, showcasing its ARCUS® genome editing platform. The schedule includes the Wells Fargo Virtual Healthcare Conference on September 10, 2020, at 12:40 PM ET, the H.C. Wainwright Annual Global Investment Conference on September 14, 2020, at 1:30 PM ET, and the Morgan Stanley Global Healthcare Conference on September 17, 2020, at 8:45 AM ET. Live webcasts will be available on the company’s website, with replays accessible for 30 days.

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Precision BioSciences (Nasdaq: DTIL) announced its Q2 2020 financial results and updates on clinical trials. The company initiated a Phase 1/2a trial for PBCAR269A, a CAR T candidate for multiple myeloma. However, patient enrollment delays related to COVID-19 have postponed updated interim data for PBCAR0191 until Q4 2020. Financially, total revenue decreased to $1.1 million from $5.4 million YoY, driven by reduced collaboration revenue. Operating expenses rose, resulting in a net loss of $32.7 million, or $(0.63) per share, compared to $(0.39) per share in 2019.

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Precision BioSciences, a clinical-stage biotechnology firm, is set to report its Q2 2020 financial results on August 13, 2020. The company's ARCUS® genome editing platform aims to enhance therapeutic safety and efficacy, focusing on CAR T immunotherapy and gene correction therapies for genetic diseases. Additionally, CEO Matt Kane and CMO Chris Heery will represent the company at the William Blair Biotech Focus Conference on August 6 and the BTIG Virtual Biotechnology Conference on August 10. Live presentations will be available on their official website.

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Precision BioSciences (Nasdaq: DTIL) announced it will regain full rights to its in vivo chronic hepatitis B virus (HBV) program previously developed in collaboration with Gilead Sciences. The company valued the collaboration, which is set to conclude on September 4, 2020, and anticipates no changes to its cash runway. As of March 31, 2020, cash and cash equivalents stood at $154.2 million, expected to fund operations into mid-2021. ARCUS gene editing has shown promise in targeting HBV, with preclinical data demonstrating significant effectiveness in knocking down HBV genomes.

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Precision BioSciences (Nasdaq: DTIL) has initiated a Phase 1/2a clinical trial for its third allogeneic CAR T therapy candidate, PBCAR269A, targeting relapsed/refractory multiple myeloma. The first patient has been dosed, with the trial emphasizing the use of clinical materials produced at the company's in-house facility. PBCAR269A has shown promise in preclinical models, effectively reducing BCMA+ tumor cells without causing graft-versus-host disease. The FDA has granted it Orphan Drug Designation for multiple myeloma treatment.

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Precision BioSciences (DTIL), a clinical-stage biotechnology firm, announced its participation in two upcoming investor conferences. The Jefferies Virtual Healthcare Conference will take place on June 3, 2020, where CEO Matt Kane will speak from 9:30 AM to 9:55 AM ET. Following that, the company will present at the Goldman Sachs 41st Annual Global Healthcare Conference on June 11, 2020, with Kane speaking from 8:50 AM to 9:30 AM ET. Live webcasts can be accessed on the company’s website, with replays available for 30 days post-presentation.

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FAQ

What is the current stock price of Precision Biosciences (DTIL)?

The current stock price of Precision Biosciences (DTIL) is $4.7 as of March 28, 2025.

What is the market cap of Precision Biosciences (DTIL)?

The market cap of Precision Biosciences (DTIL) is approximately 35.3M.

What is the primary focus of Precision Biosciences?

Precision Biosciences focuses on developing gene editing solutions using its ARCUS platform to address both human diseases and agricultural challenges.

How does the ARCUS genome editing platform differentiate from traditional methods?

The ARCUS platform is distinguished by its compact enzyme design, which facilitates efficient delivery to a wide range of cells and tissues, potentially reducing off-target effects.

In which markets does Precision Biosciences operate?

The company operates in the biotechnology sector with a dual focus on therapeutic development for human diseases and innovative solutions for agricultural applications.

What role do collaborations play in the company’s strategy?

Collaborations with academic institutions, research centers, and industry partners are essential for validating the ARCUS platform and expanding its practical applications.

How does Precision Biosciences ensure the safety and efficacy of its products?

The company employs rigorous quality control, comprehensive validation processes, and adheres to strict regulatory frameworks to maintain high standards in its genome editing applications.

What makes the ARCUS platform a unique tool in genome editing?

Its unique structural design allows for versatile delivery using both viral and non-viral methods, granting it the flexibility to target diverse cell types efficiently.

How is Precision Biosciences positioned within the competitive biotechnology landscape?

By leveraging its proprietary ARCUS platform and fostering strategic collaborations, the company has carved out a niche that emphasizes precision, innovation, and scalable gene editing solutions.

What are the potential applications of the ARCUS platform beyond human therapeutics?

Beyond therapeutic applications, the ARCUS platform has promising potential in agricultural innovation by contributing to crop improvement and food security solutions.
Precision Biosciences

Nasdaq:DTIL

DTIL Rankings

DTIL Stock Data

35.29M
7.07M
12.23%
50.49%
9.6%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
DURHAM