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Celyad Oncology (symbol: CYAD) is a clinical-stage biopharmaceutical company founded in 2007. The company is renowned for its expertise in cell-based therapies, particularly in taking them from the initial research phase to Phase III clinical trials. Celyad boasts robust manufacturing and logistical infrastructure designed to support the development of complex cell-based products.
Celyad's business model is rooted in strategic partnerships with esteemed research institutions such as Dartmouth College. These collaborations are instrumental in advancing their innovative programs from bench research to commercial applications.
One of the company's major focus areas is immuno-oncology, where it is pioneering the development of natural killer receptor T-cells (NKR-T cells) aimed at treating cancer. This unique therapeutic approach has shown promise in targeting and potentially destroying a wide variety of tumor types, positioning Celyad at the forefront of cancer treatment innovation.
Listed on Euronext Brussels, Euronext Paris, and NASDAQ under the ticker symbol CYAD, Celyad continues to gain recognition for its groundbreaking work in the biotech industry. The financial condition of the company is robust, with ongoing projects that underscore its commitment to transforming cancer care. Recent achievements and current projects reflect a steadfast dedication to clinical excellence and innovation.
Celyad Oncology SA (CYAD), a clinical-stage biotechnology firm, will participate in multiple conferences in January 2021. The H.C. Wainwright BioConnect Conference is scheduled for January 11-14, with a dedicated webcast available on January 11. Following this, Celyad will present at the Keystone eSymposia on January 25. The company is focused on developing CAR T therapies for cancers and has received funding from the Walloon Region of Belgium to advance its projects. Further details can be found on their official website.
Celyad Oncology SA (NASDAQ: CYAD) announced the successful dosing of the first patient in the expansion cohort of the Phase 1 alloSHRINK trial for CYAD-101, designed for refractory metastatic colorectal cancer. Preliminary data is expected in the first half of 2021. Dr. Eric Van Cutsem noted the historical challenges CAR T therapies faced in solid tumors, while Celyad's CYAD-101 aims to improve clinical outcomes using a non-gene edited, allogeneic CAR-T strategy. The trial will assess the safety and efficacy of CYAD-101 with FOLFIRI chemotherapy.
Celyad Oncology has announced significant updates regarding its CAR T candidates. The first patient has been dosed with CYAD-211 in the Phase 1 IMMUNICY-1 trial, indicating a key milestone in developing therapies for refractory multiple myeloma. Preclinical results show strong antitumor activity without Graft-versus-Host Disease. Meanwhile, the company has discontinued development of CYAD-01 due to clinical futility observed in the Phase 1 THINK trial. Encouraging initial results for CYAD-02 were reported in the ongoing CYCLE-1 trial.
Celyad Oncology has initiated the Phase 1 IMMUNICY-1 trial, dosing its first patient with CYAD-211, an innovative CAR T therapy targeting BCMA for relapsed/refractory multiple myeloma. The trial will assess safety and efficacy across various dose levels. The company secured €3.4 million in non-dilutive funding from SPW-Recherche to support CYAD-211's development. Preliminary data from the trial is anticipated in the first half of 2021, aiming to address the high unmet need for effective treatments in multiple myeloma.
Celyad Oncology SA (Euronext & Nasdaq: CYAD) announced that CEO Filippo Petti will participate in a fireside chat at the virtual JMP Securities Hematology Summit on December 16, 2020, at 10:00 a.m. ET / 4:00 p.m. CET. A live and archived webcast will be available on the company's website. Celyad Oncology focuses on developing chimeric antigen receptor T cell (CAR T) therapies for cancer, with a pipeline of allogeneic and autologous candidates targeting hematological malignancies and solid tumors. Founded in 2007, the company is based in Mont-Saint-Guibert, Belgium and New York, NY.
Celyad Oncology (CYAD) provided a business update for Q3 2020, emphasizing advancements in its clinical pipeline. Key highlights include a partnership with MSD for a Phase 1b trial of CYAD-101 combined with KEYTRUDA in metastatic colorectal cancer (mCRC) patients. The company is set to initiate the IMMUNICY-1 trial for CYAD-211 by year-end 2020, targeting relapsed/refractory multiple myeloma. As of September 30, 2020, Celyad reported a cash position of €20 million ($23.4 million) and a net cash burn of €6.7 million ($7.8 million), confirming sufficient funds through Q3 2021.
Celyad Oncology (CYAD) announced that three abstracts were accepted for presentation at the 62nd American Society of Hematology Annual Meeting, occurring virtually from December 5-8, 2020. The abstracts will focus on the company’s CAR T candidates: the allogeneic CYAD-211 targeting BCMA, and the autologous CYAD-01 and CYAD-02 based on the NKG2D receptor. The findings will be published in the November issue of the journal Blood. CYAD-211 has received FDA clearance for its IND application, representing progress in CAR T therapy development for multiple myeloma and related cancers.
Celyad Oncology SA (Euronext & Nasdaq: CYAD) has announced its participation in three upcoming healthcare conferences in November 2020. The events are: Bryan, Garnier & Co. Virtual European Healthcare Conference on November 16, Jefferies Virtual London Healthcare Conference on November 17 at 2:55 p.m. ET, and SVB Leerink Oncology 1x1 Day on November 19. The company focuses on developing CAR T therapies for cancer, supported by the Walloon Region funding. Investors can find more details on Celyad's website.
Celyad Oncology (NASDAQ:CYAD) has announced a collaboration with MSD to conduct the Phase 1b KEYNOTE-B79 clinical trial. This trial will investigate the investigational allogeneic CAR T candidate, CYAD-101, in combination with MSD's KEYTRUDA® for treating refractory metastatic colorectal cancer patients. The collaboration aims to leverage the complementary mechanisms of both therapies, potentially addressing unmet needs in microsatellite stable disease. Encouraging results from the alloSHRINK trial provide a positive backdrop for this initiative.
Celyad Oncology, a clinical-stage biotechnology company, announced that CEO Filippo Petti will participate in a fireside chat at the Jefferies Cell Therapy Summit on October 5, 2020, at 11:00 a.m. EDT. The event will be available for investors to listen to via a live webcast on the company's website, with an archived replay accessible for 30 days. Celyad focuses on developing CAR T cell therapies for cancer, including allogeneic and autologous candidates for treating hematological malignancies and solid tumors. The company, founded in 2007, is based in Belgium and New York.
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