Curevac B.V. Stock Price, News & Analysis

CureVac, in collaboration with GSK, announced promising preclinical results for a bivalent COVID-19 vaccine candidate targeting the Beta and Delta variants. The study revealed that this bivalent mRNA vaccine generated comparable neutralizing antibody levels to monovalent candidates while demonstrating significantly enhanced neutralization against the Omicron variant. Conducted on mice, the bivalent approach showed strong immune responses and reduced viral loads. This technology could pave the way for broader protection against evolving variants.

CureVac has entered a contract with the German government to ensure mRNA vaccine manufacturing capacity until 2029 in response to potential health emergencies. The agreement allows for the production of up to 80 million doses during public health crises. Following a two-year setup period, the federal government will pay an annual standby fee to keep the manufacturing capacity ready, thereby enhancing pandemic preparedness. This partnership emphasizes the significance of mRNA technology in swiftly addressing future infectious disease threats.

CureVac and GSK have initiated a Phase 1 dose-escalation study for their second-generation COVID-19 vaccine candidate CV2CoV in the U.S., with the first participant dosed. This trial is crucial to evaluate the candidate's safety and immune response, building on promising preclinical data that suggests better efficacy compared to the first-generation vaccine. The study aims to enroll 210 healthy adults, with results anticipated in the second half of 2022, marking a significant step in advancing mRNA vaccine technology.

CureVac N.V. (NASDAQ:CVAC) has launched CureVac RNA Printer GmbH, a wholly-owned subsidiary designed to enhance the development and operational capacity of The RNA Printer(R), an automated RNA vaccine and therapeutic manufacturing solution. This initiative aims to facilitate rapid access to mRNA technology, particularly in pandemic situations and personalized therapies. Dr. Markus Bergmann has been appointed General Manager, bringing extensive expertise in business development and a medical background. The announcement highlights CureVac's commitment to expanding its footprint in the mRNA market.

CureVac (NASDAQ: CVAC) has initiated a Phase 1 study for its seasonal influenza mRNA vaccine candidate CVSQIV, dosing the first participant in Panama. This vaccine, developed in partnership with GSK, employs a multivalent approach to target four different influenza strains using non-chemically modified mRNA. The study aims to enroll up to 240 healthy adults to assess the safety and immune response. The collaboration focuses on enhancing mRNA vaccine technologies for infectious diseases, building on the successful application during the COVID-19 pandemic.

CureVac N.V. (NASDAQ:CVAC) announced the resignation of Chief Technology Officer Dr. Mariola Fotin-Mleczek, effective January 31, 2022, after nearly 16 years with the company. She is transitioning to a family business in Poland. Dr. Igor Splawski, Chief Scientific Officer, will lead the continued development of CureVac's mRNA technology. The company's innovative mRNA platform has contributed significantly to medical advancements, including vaccines and therapies across various therapeutic areas. CureVac has a strong pipeline and is focused on leveraging its mRNA technology for future growth.

BERLIN, GERMANY / ACCESSWIRE / January 13, 2022 / dievini and the Federal Republic of Germany have amended their shareholders' agreement regarding CureVac N.V. (NASDAQ:CVAC). This update follows the succession planning for Dietmar Hopp's estate, resulting in dievini's ownership being transferred to the Hopp family. The agreement details shareholder voting behavior and board appointments. dievini plans to sell CureVac shares to finance restructuring, although no current sales to third parties are expected. dievini holds about 42% of CureVac's common shares.

CureVac N.V. (NASDAQ: CVAC) announced its strategic shift towards developing a second-generation mRNA COVID-19 vaccine, CV2CoV, in collaboration with GSK, following the withdrawal of its first-generation candidate, CVnCoV, from regulatory review. The company reported a cash position of €1.06 billion as of September 30, 2021, despite a substantial increase in operating losses, which reached €143.1 million for Q3 2021. Promising preclinical results published in Nature show CV2CoV's immune response is comparable to an approved mRNA vaccine, enhancing CureVac's position in the mRNA vaccine space.

CureVac (NASDAQ:CVAC) has published new preclinical data for its second-generation COVID-19 vaccine candidate, CV2CoV, developed with GSK, in Nature. The study shows antibody levels after vaccination with 12μg of CV2CoV are comparable to those following a 30μg dose of Comirnaty® (Pfizer/BioNTech). CV2CoV demonstrated enhanced immune responses, with better neutralizing capacity against variants like Delta. This research underscores the potential of non-chemically modified mRNA technology in vaccine development.