Welcome to our dedicated page for CytomX Therapeutics news (Ticker: CTMX), a resource for investors and traders seeking the latest updates and insights on CytomX Therapeutics stock.
CytomX Therapeutics, Inc. (Nasdaq: CTMX) is a leading oncology-focused biopharmaceutical company pioneering a novel class of investigational antibody therapeutics with its proprietary Probody® technology platform. Based in South San Francisco, CytomX leverages this platform to develop cancer immunotherapies that target clinically-validated and novel oncological targets. The unique Probody® therapeutics are designed to enhance the tumor-targeting capabilities of antibodies while minimizing toxicity in healthy tissues.
Probody® therapeutics operate by taking advantage of the unique conditions present in the tumor microenvironment, thereby improving both the efficacy and safety profiles of monoclonal antibody treatments, including cancer immunotherapies, antibody-drug conjugates (ADCs), and T-cell-recruiting bispecific antibodies. The company's innovative pipeline includes several promising candidates currently in various stages of development.
Among its recent achievements, CytomX is advancing its lead programs, CX-2051 and CX-801, into Phase 1 clinical studies. CX-2051 is an ADC that targets EpCAM-expressing tumors, including colorectal cancer, while CX-801 aims to overcome limitations associated with interferon-directed therapies. These candidates exemplify the versatility and productivity of CytomX's Probody® platform, promising significant advancements in cancer treatment.
CytomX has established strategic collaborations with industry leaders such as Amgen, Astellas, Bristol Myers Squibb, Regeneron, and Moderna to further enhance its research and development capabilities. As a result, the company is well-positioned to lead in the development of conditionally activated biologics designed for localized action within tumor microenvironments.
Financially, CytomX has made significant strides in cost control and strategic allocation of capital towards lead pipeline programs. In 2023, the company reduced its total operating expenses by $46.8 million, driven by workforce reductions and strategic pipeline prioritization. Research and development expenses decreased by $34.0 million, while general and administrative expenses decreased by $12.8 million.
For more information about CytomX and its innovative approach to cancer treatment, visit their official website at www.cytomx.com and follow them on LinkedIn and Twitter.
CytomX Therapeutics (Nasdaq: CTMX) announced on January 18, 2022, the granting of stock options for 127,000 shares to four new employees at an exercise price of $3.83 per share. These options are part of the 2019 Employment Inducement Incentive Plan approved by the Company’s board in August 2020. CytomX specializes in conditionally activated therapeutics, focusing on various oncology treatments, particularly through its Probody technology platform. The company’s current clinical pipeline includes several investigational drugs aimed at treating difficult cancer types.
CytomX Therapeutics announced FDA clearance of the IND application for CX-904, its first T-cell-engaging bispecific antibody and sixth Probody candidate to enter clinical trials. Co-developed with Amgen, CX-904 is targeted at treating advanced solid tumors by selectively engaging T cells in the tumor microenvironment. The company emphasizes the innovative aspects of CX-904, which shows potent anti-tumor activity in preclinical studies and aims to initiate a Phase 1 dose-escalation study soon. CytomX aims to redefine cancer treatment with its conditionally activated therapeutics.
CytomX Therapeutics (Nasdaq: CTMX) announced that Sean McCarthy will present virtually at the 40th Annual J.P. Morgan Healthcare Conference on January 12 at 3:00 p.m. ET. The presentation will be available live on CytomX’s website, with an archived replay accessible for 30 days post-event. CytomX is known for its innovative conditionally activated biologics aimed at enhancing cancer treatment. Their pipeline includes investigational therapies like praluzatamab ravtansine and CX-2029, currently in Phase 2 studies targeting hard-to-treat cancers.
CytomX Therapeutics (CTMX) announced preliminary Phase 2 results for CX-2029, an antibody-drug conjugate targeting advanced squamous non-small cell lung cancer (sqNSCLC) and head and neck squamous cell carcinoma (HNSCC). In sqNSCLC, the objective response rate (ORR) was 18.8%, with a disease control rate (DCR) of 87.5%. HNSCC patients showed an ORR of 4.0% and a DCR of 56.0%. No new safety signals were detected, maintaining a favorable adverse event profile. The company continues to enroll patients and is optimistic about future data releases.
CytomX Therapeutics, Inc. (Nasdaq: CTMX) announced that CEO Sean McCarthy will participate in virtual fireside chats at two investor conferences in November 2021. The Jefferies Global Healthcare Conference is scheduled for November 18, with the chat available online at 3:00 a.m. ET. The Piper Sandler Virtual Healthcare Conference will follow on November 30, with the chat accessible at 10:00 a.m. ET. Archived replays will be available on the company's website for 30 days. CytomX is pioneering conditionally activated therapeutics focusing on oncology.
CytomX Therapeutics (CTMX) reported its third quarter 2021 financial results, showcasing a revenue of $18 million, consistent with 2020 figures. The company is on track to release initial data from the Phase 2 studies of CX-2029 in Q4 2021 and praluzatamab ravtansine (CX-2009) in 2022. R&D expenses increased to $29 million due to clinical trials and related costs. The company maintains a strong cash position of $336 million. Additionally, CX-904's IND filing is anticipated in late 2021, emphasizing CytomX’s commitment to advancing its conditionally activated therapeutics.
CytomX Therapeutics (CTMX) announced the presentation of preclinical data on a conditionally activated interferon alpha-2b at the SITC 2021 Annual Meeting from November 12-14, 2021. The data highlights the safety and anti-cancer activity of this treatment, showcasing the potential of CytomX's Probody® technology platform. This innovative approach aims to minimize toxicity while enhancing therapeutic efficacy against cancer. With a robust clinical pipeline, CytomX is focused on developing safer, more effective therapies for patients.
CytomX Therapeutics, Inc. (Nasdaq: CTMX) announced their upcoming third quarter 2021 financial results on November 4, 2021, following U.S. market closure. A conference call at 5:00 p.m. ET will provide insights into the results and corporate updates. CytomX is focused on developing conditionally activated therapeutics via their Probody® technology platform, aiming to improve cancer therapy effectiveness while minimizing toxicity. The company collaborates with industry leaders like AbbVie and Bristol Myers Squibb, having a pipeline with multiple assets in Phase 2 clinical trials.
CytomX Therapeutics (Nasdaq: CTMX), a biopharmaceutical company focused on oncology, announced the grant of stock options to six new employees on October 15, 2021. A total of 177,000 shares were offered at an exercise price of $5.14, matching the closing price on the grant date. The options are part of the 2019 Employment Inducement Incentive Plan, approved by the board in August 2020. CytomX specializes in conditionally activated therapeutics, employing its Probody® technology platform, to target cancer with minimized toxicity.
CytomX Therapeutics (Nasdaq: CTMX) has appointed Alan Ashworth, Ph.D., a distinguished cancer researcher, to its board of directors. Dr. Ashworth, known for identifying the BRCA2 gene and developing PARP inhibitors, brings extensive experience to advance CytomX's clinical pipeline. President Sean McCarthy emphasized Dr. Ashworth's expertise in translational sciences will be valuable as the company targets key Phase 2 milestones. CytomX focuses on conditionally activated therapeutics using its Probody technology to improve cancer treatment outcomes while minimizing toxicity.
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