Welcome to our dedicated page for Cytomx Therapeutics news (Ticker: CTMX), a resource for investors and traders seeking the latest updates and insights on Cytomx Therapeutics stock.
CytomX Therapeutics Inc (CTMX) is a clinical-stage biopharmaceutical pioneer developing conditionally activated cancer therapies through its probody technology platform. This dedicated news hub provides investors and researchers with essential updates on clinical advancements, strategic collaborations, and therapeutic innovations in oncology.
Access real-time updates on CTMX's probody-based candidates, including antibody drug conjugates and T-cell engagers. The platform centralizes critical developments such as trial milestones, partnership expansions with industry leaders like Astellas and Merck, and financial disclosures - all vital for informed analysis of this innovative oncology company.
Key content categories include clinical program progress, regulatory updates, scientific presentations, and corporate financial results. Each update is curated to highlight how CTMX's tumor-activated therapies aim to improve cancer treatment safety profiles while maintaining therapeutic efficacy.
Bookmark this page for streamlined access to verified CTMX developments. Regularly updated with official press releases and objective reporting, it serves as your primary resource for tracking advancements in conditionally activated cancer immunotherapies.
CytomX Therapeutics (NASDAQ:CTMX) has announced the pricing of an underwritten public offering of 76,923,076 shares of common stock at $1.30 per share, aiming to raise approximately $100 million in gross proceeds. The offering, expected to close on May 13, 2025, features participation from notable investors including Longitude Capital, OrbiMed, Venrock Healthcare Capital Partners, Vivo Capital, and RTW Investments.
The company plans to use the proceeds for research and development, general corporate purposes, and working capital needs. Jefferies and Piper Sandler are serving as joint book-running managers for the offering, which is being conducted through an effective shelf registration statement filed with the SEC.
CytomX Therapeutics (NASDAQ: CTMX), a company specializing in masked, conditionally activated biologics, has scheduled its first quarter 2025 financial results announcement for Monday, May 12, 2025, before U.S. markets open. The company will host a conference call and webcast at 8:00 a.m. ET / 5:00 a.m. PT following the announcement.
Interested participants can access the live webcast through CytomX's investor relations website and are advised to register for the conference call at least 10 minutes before it begins. A replay of the webcast will be made available on the company's website after the event.
CytomX Therapeutics and Moderna have unveiled promising preclinical data for their collaborative development of an mRNA-encoded masked IL-12 molecule at the AACR Annual Meeting in Chicago.
The breakthrough combines CytomX's PROBODY® masking technology with Moderna's mRNA expertise to create a novel cancer treatment approach. The key innovation lies in developing an IL-12 therapeutic that can be selectively activated within the tumor microenvironment while minimizing systemic activity.
Key highlights:
- Successfully demonstrated proof of concept for mRNA encoded masked molecule in cancer treatment
- Achieved enhanced tolerability while maintaining anti-tumor efficacy
- Addresses previous limitations of IL-12's clinical use due to inflammatory toxicity
The research findings will be presented in Poster #3127/12 on April 28, 2025, highlighting how this innovative combination of technologies could potentially overcome traditional IL-12 therapy limitations.
CytomX Therapeutics (CTMX) reported its 2024 financial results, highlighting progress in its clinical pipeline. The company's lead program, CX-2051, a PROBODY Topo-1 ADC targeting EpCAM in advanced colorectal cancer, is advancing with initial Phase 1a data expected in 1H 2025. The Phase 1 study is currently at the seventh dose level.
Financial highlights include total revenue of $138.1 million for 2024, up from $101.2 million in 2023, driven by research program collaborations. The company ended 2024 with $100.6 million in cash and investments. Operating expenses increased to $113.1 million from $107.7 million, primarily due to a $5.0 million milestone payment to AbbVie.
In January 2025, CytomX announced a 40% workforce reduction to focus resources on CX-2051. The company's cash runway extends into Q2 2026. A new $5 million milestone payment was triggered in February 2025 from the Astellas collaboration.
CytomX Therapeutics (Nasdaq: CTMX), a pioneer in masked, conditionally activated biologics, has announced its participation in the upcoming Barclays 27th Annual Global Healthcare Conference.
The company's CEO and chairman, Sean McCarthy, D.Phil., is scheduled to deliver a presentation on Wednesday, March 12, 2025, at 3:00 p.m. ET. Investors and interested parties can access a live webcast of the presentation through the Events and Presentations section of CytomX's website at www.cytomx.com.
Additionally, the management team will be available for one-on-one meetings with registered conference attendees.
CytomX Therapeutics (Nasdaq: CTMX), a company specializing in masked, conditionally activated biologic therapeutics, has scheduled the release of its fourth quarter and full year 2024 financial results for March 6, 2025, after U.S. markets close.
The company will host a conference call and webcast at 5:00 p.m. ET / 2:00 p.m. PT on the same day. Interested participants can access the webcast through CytomX's investor relations website and are advised to register at least 10 minutes before the call begins.
CytomX Therapeutics (Nasdaq: CTMX), a pioneering company in masked, conditionally activated biologics, has announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference. Sean McCarthy, D.Phil., the company's CEO and chairman, is scheduled to deliver a presentation on Wednesday, January 15, 2025, at 1:30 p.m. PT.
The presentation will be accessible through a live webcast on the Events and Presentations section of CytomX's website. Additionally, the management team will be available for individual meetings with registered conference investors.
CytomX Therapeutics (NASDAQ: CTMX) has announced its 2025 strategic pipeline priorities, focusing primarily on CX-2051, their lead wholly-owned EpCAM PROBODY ADC program for advanced metastatic colorectal cancer. Initial Phase 1a clinical data is expected in H1 2025.
The company is implementing significant organizational changes, including a 40% reduction in headcount, primarily affecting non-partnered early research and administrative functions. These changes, along with focused clinical development priorities, are expected to extend their cash runway into Q2 2026. As of Q3 2024, the company had $117.6 million in cash and investments.
Three main clinical programs are in progress: CX-2051 (currently in sixth dose escalation cohort), CX-904 (enrolled over 70 patients), and CX-801 (Phase 1 dose escalation in metastatic melanoma). The company maintains research collaborations with Amgen, Astellas, Bristol Myers Squibb, Moderna, and Regeneron.
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