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Castle Biosciences - CSTL STOCK NEWS

Welcome to our dedicated page for Castle Biosciences news (Ticker: CSTL), a resource for investors and traders seeking the latest updates and insights on Castle Biosciences stock.

Company Overview

Castle Biosciences Inc. (CSTL) is a commercial-stage biotechnology company with a specialized focus on diagnostic tests for cancer. Leveraging advancements in genomic testing and personalized medicine, the company provides clinicians with actionable, clinically validated genomic information across a range of cancers. Through its innovative and objective testing protocols, Castle Biosciences aids in the accurate diagnosis and treatment planning of cancer patients, thereby contributing to improved patient outcomes.

Core Business and Test Portfolio

The core business of Castle Biosciences is anchored in the development and commercialization of state-of-the-art diagnostic tests. The company’s tests are meticulously developed through collaborative efforts with key members of the oncology community, ensuring that each test meets rigorous clinical standards. Its portfolio includes tests designed to aid in the treatment of cutaneous and uveal melanoma, esophageal adenocarcinoma, mesothelioma, and glioma, along with specialized tools such as DecisionDx assays. Additionally, the company has diversified into fields beyond dermatological cancers, offering tests in gastroenterology, ophthalmology, and even pharmacogenomics to guide optimal therapeutic choices for mental health conditions.

Diagnostic Innovation and Genomic Insights

At the heart of Castle Biosciences' offerings is its commitment to incorporating genomic insights into diagnostic testing. By utilizing sophisticated genomic analysis techniques, the company enables physicians to access personalized diagnostic information that is critical for making informed treatment decisions. This approach not only underscores the reliability of its tests but also demonstrates the company’s dedication to bridging innovative science with practical clinical applications. The integration of genomic data helps to stratify patients according to risk and potential treatment response, thereby supporting more targeted and effective clinical interventions.

Research and Clinical Collaboration

Castle Biosciences has established a robust research framework that is continually advancing the field of diagnostic oncology. The company maintains active research programs in several high-need areas such as rectal cancer and soft tissue sarcoma, reflecting its commitment to addressing under-served cancer types. Collaborations with prominent figures and institutions in the oncology community further validate the clinical utility of its tests, ensuring that the company’s offerings are reflective of the latest scientific insights and clinical best practices.

Market Position and Competitive Differentiation

Within the competitive landscape of diagnostic and genomic testing, Castle Biosciences distinguishes itself by offering a unique blend of technical innovation and deep clinical validation. Its focus on objective and evidence-based testing processes positions it as an informative resource for healthcare professionals seeking enhanced diagnostic precision. This focus is encapsulated in its transparent and rigorous approach to both test development and clinical collaboration. Such methodological clarity not only builds trust with its clinical partners but also reinforces the company’s reputation within the broader biotechnology and diagnostics sectors.

Operational Model and Clinical Impact

The company operates on a model that emphasizes the creation and delivery of clinically actionable data. Its operational strategy centers on close engagement with the oncology community to continuously refine its testing solutions. By aligning its research and development efforts with real-world clinical needs, Castle Biosciences ensures that its tests have a direct and significant impact on patient care. Moreover, the company’s commitment to precision medicine and genomic diagnostics is reflected in every aspect of its operations, from the initial discovery phase to test commercialization and clinical adoption.

Expertise and Industry Terminology

Castle Biosciences leverages industry-specific terminology and technological expertise to communicate its value proposition clearly. Terms such as "genomic testing," "personalized medicine," and "clinically actionable insights" are integral to describing its diagnostic methodology. This intentional use of precise language not only highlights the company’s technical proficiency but also reinforces its commitment to delivering scientifically sound and clinically relevant products.

Summary

In summary, Castle Biosciences Inc. stands as a pivotal entity in the field of cancer diagnostics. Its focus on integrating personalized genomic information into clinical decision-making facilitates enhanced treatment strategies for various cancer types. With a strong foundation built on clinical collaboration, ongoing research, and innovative test development, the company continues to provide healthcare professionals with the tools necessary for informed and effective patient care.

Rhea-AI Summary

Castle Biosciences, Inc. (Nasdaq: CSTL) will announce its fourth-quarter and full-year financial results for 2020 after the market closes on March 8, 2021. A conference call and webcast will follow at 4:30 p.m. Eastern time to discuss these results and a corporate update. Interested parties can access the live webcast through the company’s Investor Relations page or by phone. Castle Biosciences focuses on providing personalized genomic information for skin cancer treatment decisions, offering tests for various melanoma types and other dermatologic diseases.

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Castle Biosciences (Nasdaq: CSTL) announced that CEO Derek Maetzold will present at two investor conferences. The first is the BTIG Virtual MedTech Conference on Feb. 17, 2021, at 10:30 a.m. ET, followed by the 10th Annual SVB Leerink Global Healthcare Conference on Feb. 24, 2021, at 10:00 a.m. ET. Live webcasts of the presentations will be available on Castle's website, with replays accessible for two weeks afterward. Castle focuses on providing personalized genomic information to enhance treatment decisions for skin cancer.

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Castle Biosciences (Nasdaq: CSTL) announced the presentation of virtual posters at the 19th Annual South Beach Symposium, highlighting its gene expression profile tests for skin cancer. Key studies include DecisionDx-Melanoma, which predicts melanoma metastasis risk, revealing that 75% of patients with T1b tumors could avoid sentinel lymph node biopsy, potentially saving $120 million in healthcare costs. DecisionDx DiffDx-Melanoma showed high diagnostic accuracy (99.1% sensitivity) and improved clinician confidence. DecisionDx-SCC aids in predicting metastasis risk in high-risk cutaneous SCC patients, improving management decisions.

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Castle Biosciences, Inc. (Nasdaq: CSTL) announced poster presentations featuring data on its skin cancer gene expression profile tests at the 18th Annual Winter Clinical Dermatology Conference from Jan. 15 – 24, 2021. The tests include DecisionDx®-Melanoma, which predicts melanoma metastasis risk, and DecisionDx® DiffDx™-Melanoma, designed for classifying difficult lesions. Key findings reveal DecisionDx-Melanoma significantly predicts sentinel lymph node positivity, while DecisionDx DiffDx-Melanoma boasts 98% sensitivity and 100% specificity in head and neck lesions.

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Castle Biosciences (Nasdaq: CSTL) released preliminary performance results for Q4 and full-year 2020. Despite COVID-19 challenges, the company reported growth in DecisionDx®-Melanoma test reports, delivering 4,246 in Q4 and 16,232 for the year. They expanded their skin cancer product suite and launched the DecisionDx DiffDx-Melanoma test. The total addressable market for its tests is now estimated at $2 billion. Key financial highlights include a public offering that raised $266.8 million, boosting cash reserves to approximately $410 million by year-end.

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Castle Biosciences, Inc. (Nasdaq: CSTL) announced that Derek Maetzold, CEO, will present a company overview at the 23rd Annual Needham Virtual Growth Conference on January 15, 2021, at 11:30 a.m. Eastern time. A live audio webcast of the presentation will be accessible on Castle Biosciences’ website, with a replay available for two weeks post-event. The company specializes in providing personalized genomic information to enhance cancer treatment decisions, offering tests for various skin cancers including melanoma and squamous cell carcinoma.

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Castle Biosciences (Nasdaq: CSTL) has fully prepaid its term loan facility, improving its financial standing. The prepayment of approximately $21.6 million, which includes principal and interest, signifies a strategic move post its successful equity financing. This action terminates all obligations under the loan agreement, enhancing cash savings and enabling further development of its product pipeline. The company focuses on dermatologic cancer diagnostics and aims to leverage its strengthened financial position to support and grow its marketed products in 2021.

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Castle Biosciences (Nasdaq: CSTL) has successfully closed its underwritten public offering, issuing 4,600,000 shares of common stock at a price of $58.00 per share. This includes the full exercise of the underwriters' option for an additional 600,000 shares, totaling gross proceeds of $266.8 million before expenses. The offering was managed by SVB Leerink and Baird, among others. The securities were offered under a shelf registration effective since December 14, 2020, with final prospectus details available through the SEC.

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Castle Biosciences (CSTL) has priced its public offering of 4,000,000 shares at $58.00 each, expected to yield gross proceeds of $232 million. Additionally, underwriters have a 30-day option for 600,000 more shares. Closing is anticipated around December 18, 2020, subject to conditions. The offering is made under a previously effective registration statement with the SEC. SVB Leerink and Baird are leading the offering, with other firms assisting.

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Castle Biosciences (Nasdaq: CSTL) has initiated a proposed underwritten public offering to sell $125 million of its common stock. The company plans to allow underwriters a 30-day option to purchase an additional $18.75 million in shares. All shares will be offered by Castle. The offering is subject to market conditions and completion timing is uncertain. SVB Leerink and Baird are leading the offering, with joint bookrunning management. This offering is part of a shelf registration statement filed with the SEC, aiming to enhance financial resources for growth.

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FAQ

What is the current stock price of Castle Biosciences (CSTL)?

The current stock price of Castle Biosciences (CSTL) is $19.78 as of April 1, 2025.

What is the market cap of Castle Biosciences (CSTL)?

The market cap of Castle Biosciences (CSTL) is approximately 563.7M.

What is the primary focus of Castle Biosciences?

Castle Biosciences specializes in developing diagnostic tests that provide actionable genomic insights to aid in the diagnosis and treatment of various cancers. Its product portfolio includes tests for conditions such as cutaneous melanoma, uveal melanoma, and other cancer types.

How does Castle Biosciences incorporate genomic information in its diagnostics?

The company leverages advanced genomic testing techniques to generate personalized data that guides clinical decisions. This detailed genomic analysis helps physicians make more precise treatment choices for cancer patients.

Which cancer types does Castle Biosciences target with its tests?

Castle Biosciences offers diagnostic tests for a range of cancers, including cutaneous and uveal melanoma, esophageal adenocarcinoma, mesothelioma, and glioma. Additionally, the company is actively researching tests for other under-served cancers such as rectal cancer and soft tissue sarcoma.

What differentiates Castle Biosciences' diagnostic tests from others in the market?

The company sets itself apart by integrating comprehensive genomic data with clinical validation, ensuring its tests deliver reliable and actionable insights. Its close collaboration with leading oncology experts further reinforces the credibility and precision of its diagnostic tools.

How does Castle Biosciences maintain clinical relevance in its test development?

Castle Biosciences collaborates with respected members of the oncology community to align its research and test development with current clinical needs. This partnership approach ensures that its diagnostics remain both innovative and grounded in clinical best practices.

What types of diagnostic offerings does the company provide beyond cancer testing?

In addition to cancer diagnostics, Castle Biosciences has expanded its portfolio to include a pharmacogenomics test aimed at guiding optimal drug treatment for mental health conditions such as depression and anxiety. This diversification demonstrates the company’s commitment to personalized medicine across different medical disciplines.
Castle Biosciences

Nasdaq:CSTL

CSTL Rankings

CSTL Stock Data

563.72M
27.55M
3.35%
93.97%
6.48%
Diagnostics & Research
Services-medical Laboratories
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United States
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