Champions Oncology Announces a Partnership with Fannin Innovation to Jointly Develop Therapeutic Raptamer Drug Conjugates

Rhea-AI Summary

Champions Oncology, Inc. (CSBR) has announced a new therapeutic co-development partnership with Fannin Innovation Studio. This collaboration aims to combine Champions' Lumin platform with Fannin's Raptamer platform to create next-generation Raptamer Drug Conjugates (RDCs), specifically targeting tumors such as non-small cell lung cancer and head and neck cancer. The partnership will share ownership of developments and initiate a joint venture after meeting specific milestones. The collaboration harnesses AI-driven analytics and unique platforms to expedite clinical evaluation of novel therapeutic targets.

Positive

• Formation of a partnership with Fannin Innovation Studio for co-developing Raptamer Drug Conjugates.
• Access to innovative therapeutic targets via Champions' Lumin platform.
• Focus on treating critical tumor types such as non-small cell lung cancer.

Negative

• None.

HACKENSACK, NJ / ACCESSWIRE / January 20, 2022 / Champions Oncology, Inc. (NASDAQ:CSBR), a leading global technology-enabled biotech that is transforming drug discovery through innovative AI-driven pharmaco-pheno-multiomic integration, announced today a therapeutic co-development partnership with Fannin Innovation Studio. The partnership will combine novel therapeutic targets identified within Champions' Lumin platform with Fannin's Therapeutic Raptamer platform to develop next generation Raptamer Drug Conjugates (RDC's). RDCs engage tumor-specific therapeutic targets at a cell's surface to deliver potent toxic payloads to the tumor, without affecting normal cells. The planned partnership will initiate with a single program focused on a previously unexplored target present in tumor indications such as non-small cell lung cancer (NSCLC), head and neck cancer, and other solid tumors. The partnership will also leverage the unique experimental platforms available at Champions to ensure rapid and efficient development towards clinical evaluation. Under the terms of this agreement, Champions and Fannin will share equal ownership of the developed therapeutic and establish a joint venture after specific development milestones are met.

Ronnie Morris, MD, President and CEO of Champions Oncology, said "We're excited to announce another partnership in drug discovery and development. Our experimental and digital research platforms continue to expand our understanding of tumor cell biology. With our AI-driven analytics, and deeply characterized dataset, we can completely reconstruct a tumor at the molecular level and identify differences between a tumor cell and normal cell. Over the past year, we have identified a considerable number of therapeutic targets that were previously overlooked using conventional methods, and we continue to scale our efforts to reveal others. The specific target being leveraged in this partnership has a profile that makes it uniquely interesting for an RDC-based therapeutic. Fannin's Raptamer Platform is a compelling approach to therapeutic discovery, and we believe this partnership is the right approach for this target. We are eager to see this program develop with our combined expertise."

Atul Varadhachary, MD, PhD, Managing Partner of Fannin Innovation Studio, noted that "Our validated Raptamer platform provides a unique opportunity to rapidly develop selective, high-affinity ligands for targeted payload delivery to a variety of tissues, including tumors. The Raptamer platform provides complementary capabilities to Champions' multiomic computational platform, and we are excited about our joint venture with Champions as well as the initial neo-antigenic target for our partnership."

About Champions Oncology
Champions Oncology is a technology-driven research organization that develops innovative therapeutics against cancer targets, offers groundbreaking research software as a service, and provides end-to-end R&D services to biopharma organizations. Champions Oncology is actively engaged in the transformation of drug discovery through a novel approach of pharmaco-pheno-multiomic integration. For more information, please visit www.ChampionsOncology.com.

Media Contact:
Rachel Bunting, MS, MBA
Sr. Director, Head of Global Marketing
Marketing@ChampionsOncology.com

Website: www.championsoncology.com
Facebook: https://www.facebook.com/championsoncology/
LinkedIn: https://www.linkedin.com/company/champions-oncology-inc-/
Twitter: https://twitter.com/ChampionsOncol1
Instagram: https://www.instagram.com/championsoncology/

About Fannin Innovation Studio
Fannin is Houston's most active biomedical development group focused on developing early-stage pharmaceutical and medical device assets, both those in-licensed in from academic institutions and those developed internally. For its portfolio companies, Fannin serves as both the management team and the early seed investor, collaborating with academic and other inventors to advance life science technology, leveraging grant funding when appropriate.

Website: www.FanninInnovation.com

LinkedIn: https://www.linkedin.com/company/fannininnovationstudio

Twitter: @FanninStudio

About Raptamer Discovery Group
Houston-based Raptamer Discovery Group (RDG), a Fannin portfolio company, will provide key services to Fannin in the co-development process. RDG specializes in the discovery and development of next-generation DNA molecules called Raptamers™. Raptamers can be developed to target small molecules, proteins, and whole cells, and they can be used as therapeutic, diagnostic or research agents. RDG has developed Raptamers for more than 60 global customers, and the company has received more than $13 million in equity investment and/or grant funding from agencies including NASA, the NIH and DARPA. Formerly known as AM Biotechnologies, RDG was acquired by Fannin in 2019. See: www.raptamer.com.

Media Contact:
Serena Miggins, MA
Business Operations Manager
Serena@FanninInnovation.com

SOURCE: Champions Oncology, Inc.

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FAQ

What is the partnership between Champions Oncology and Fannin Innovation Studio?

Champions Oncology and Fannin Innovation Studio are collaborating to co-develop Raptamer Drug Conjugates targeting various tumors, leveraging Champions' Lumin platform and Fannin's Raptamer platform.

What are Raptamer Drug Conjugates?

Raptamer Drug Conjugates (RDCs) are a targeted therapeutic approach that delivers toxic payloads specifically to tumor cells, minimizing impact on healthy cells.

Which cancers are targeted through this partnership?

The partnership initially focuses on non-small cell lung cancer, head and neck cancer, and other solid tumors.

What role does AI play in the Champions Oncology partnership with Fannin?

AI is utilized in Champions' analytics to reconstruct tumors at the molecular level and identify potential therapeutic targets.

When was the partnership between Champions Oncology and Fannin announced?

The partnership was announced on January 20, 2022.