Welcome to our dedicated page for Corvus Pharmaceuticals news (Ticker: CRVS), a resource for investors and traders seeking the latest updates and insights on Corvus Pharmaceuticals stock.
Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS) is a pioneering clinical-stage biopharmaceutical company focused on the development of novel immunotherapies to treat a broad spectrum of cancers and immune diseases. The company's core innovation is the selective inhibition of interleukin-2-inducible T cell kinase (ITK), which plays a crucial role in T cell and natural killer (NK) cell immune functions. Corvus' lead investigational product, soquelitinib (formerly CPI-818), has shown promise in optimizing T cell differentiation and enhancing immune responses against tumors, as well as in the management of autoimmune diseases.
Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed peripheral T cell lymphoma (PTCL), an aggressive and typically treatment-resistant form of non-Hodgkin’s lymphoma. The company’s focus on ITK inhibition offers a new therapeutic approach, given the lack of FDA-approved treatments for relapsed PTCL. Soquelitinib has demonstrated the ability to prevent T cell exhaustion and promote the generation of cytotoxic killer T cells, critical in cancer therapy.
In addition, Corvus is investigating soquelitinib for other immune-mediated conditions, including atopic dermatitis. The company recently initiated a randomized, double-blind Phase 1 clinical trial to evaluate soquelitinib in patients with moderate to severe atopic dermatitis, aiming to provide an oral treatment alternative to current injectable biologics.
Other promising candidates in Corvus' pipeline include ciforadenant, an adenosine A2A receptor inhibitor that disables tumors' immune evasion mechanisms, and mupadolimab, a monoclonal antibody targeting CD73. These candidates are being studied for their efficacy in combination therapies for various cancers, including head and neck cancers and non-small cell lung cancer.
Financially, Corvus maintains a strong position, having raised significant capital through direct offerings to support its clinical trials and operational needs. With cash reserves projected to fund operations into late 2025, Corvus is well-positioned to achieve substantial milestones in its clinical programs. The company continues to foster critical partnerships, including collaborations with Angel Pharmaceuticals for the Chinese market.
Latest news highlights Corvus' progress in clinical trials and strategic financing moves, underscoring its commitment to bringing innovative immunotherapies to patients in need. For more information, visit the Corvus Pharmaceuticals website.
Corvus Pharmaceuticals (CRVS) reported a business update and financial results for Q4 and the full year of 2020. They initiated a Phase 3 study for CPI-006 targeting COVID-19, which showed promising Phase 1 results with no patients requiring mechanical ventilation. Additionally, Corvus co-founded Angel Pharmaceuticals to expedite drug development in China. Financially, they ended 2020 with $44.3 million in cash, down from $78.0 million in 2019 and projected a cash burn of $46-$48 million for 2021. The company reported a net income of $27.1 million for Q4 2020.
BURLINGAME, Calif., March 05, 2021 – Corvus Pharmaceuticals (NASDAQ: CRVS) announced participation in two investor conferences this March. The H.C. Wainwright Global Life Sciences Conference is scheduled for March 9-10, 2021, featuring pre-recorded presentations and one-on-one meetings. A corporate overview by Dr. Richard A. Miller will be available on-demand starting March 9. The 33rd Annual Roth Virtual Conference follows on March 15-17, where Dr. Miller will engage in a fireside chat on March 16 and present additional insights. Webcasts will be accessible through the Corvus website.
Corvus Pharmaceuticals (NASDAQ:CRVS) completed an underwritten public offering of 9,783,660 shares at $3.50 per share, raising gross proceeds of $34.2 million. This includes 1,212,231 shares from underwriters’ partial exercise of their option. The net proceeds for Corvus stand at approximately $31.8 million after expenses. Cantor Fitzgerald & Co. and H.C. Wainwright & Co. are the joint book-running managers for the offering. The shares' offering was made under an effective registration statement with the SEC.
Corvus Pharmaceuticals (NASDAQ:CRVS) has announced the pricing of a public offering of 8,571,429 shares of common stock at $3.50 per share, totaling gross proceeds of $30 million. The offering will support the Phase 3 clinical trial of CPI-006 and the development of other product candidates. Additionally, underwriters have a 30-day option to purchase an extra 1,285,714 shares. The offering is set to close around February 17, 2021, pending customary closing conditions.
Corvus Pharmaceuticals (NASDAQ:CRVS) announced a public offering of its common stock, with all shares being sold by the company. Underwriters may purchase an additional 15% of the shares offered. The company plans to utilize the net proceeds for its Phase 3 clinical trial of CPI-006 and other product developments. The offering is subject to market conditions, and a registration statement for these securities was filed with the SEC.
Corvus Pharmaceuticals (NASDAQ: CRVS) has initiated a Phase 3 clinical trial for CPI-006, targeting hospitalized COVID-19 patients. This randomized, double-blind, placebo-controlled study aims to enroll around 1,000 participants globally, with results expected in Q4 2021. Preliminary Phase 1 results showed promising outcomes, with no patients progressing to mechanical ventilation and a median hospital discharge time of 3.5 days. CPI-006 aims to stimulate B cells for enhanced antibody production, potentially addressing SARS-CoV-2 variants. A separate Phase 2 trial is planned for CPI-818 in T-cell lymphoma.
Corvus Pharmaceuticals (NASDAQ: CRVS) reported new interim data on CPI-818 at the 62nd ASH Annual Meeting, showcasing its potential in treating T cell lymphomas and autoimmune lymphoproliferative syndrome (ALPS). The Phase 1/1b trial revealed promising anti-tumor activity, with significant tumor responses in advanced T cell malignancies. No severe treatment-related adverse events were recorded. Additionally, pre-clinical data indicated that CPI-818 could inhibit abnormal T cell activation in ALPS patients. The company plans to continue its studies and collaborate with Angel Pharmaceuticals in China.
Corvus Pharmaceuticals (CRVS) has announced new findings on its drug CPI-818 at the upcoming 62nd ASH Annual Meeting. The data includes results from a Phase 1/1b trial focused on T cell lymphoma and pre-clinical studies for treating autoimmune lymphoproliferative syndrome (ALPS). CPI-818 is an ITK inhibitor showing potential in blocking T cell activation in ALPS patients. Presentations will occur on December 5 and 6, 2020, highlighting CPI-818's efficacy and safety.
Corvus Pharmaceuticals (CRVS) announced the initiation of a pivotal Phase 2 randomized trial for CPI-006, aimed at treating COVID-19 in hospitalized patients. This trial is expected to start in December 2020, with results anticipated by mid-2021. The Phase 1 study demonstrated that CPI-006 activates a strong anti-SARS-CoV-2 antibody response and enhances patient recovery, with no reported drug-related toxicity. Key presentations highlighting the COVID-19 program will occur at the SITC Annual Meeting on November 13, 2020, showcasing CPI-006's immunotherapy potential.
Corvus Pharmaceuticals (NASDAQ: CRVS) announced the completion of patient enrollment in a Phase 1 study of CPI-006, an immunotherapy for hospitalized COVID-19 patients. Data presented at the SITC Annual Meeting indicates that CPI-006 enhances polyclonal humoral immunity, with patients showing significant antibody responses to SARS-CoV-2. Following promising results, a pivotal, randomized trial is set to begin in December 2020, with results anticipated by mid-2021. The R&D Symposium on November 12 will further detail these findings and updates on cancer programs.
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