Welcome to our dedicated page for Corvus Pharmaceuticals news (Ticker: CRVS), a resource for investors and traders seeking the latest updates and insights on Corvus Pharmaceuticals stock.
Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS) is a pioneering clinical-stage biopharmaceutical company focused on the development of novel immunotherapies to treat a broad spectrum of cancers and immune diseases. The company's core innovation is the selective inhibition of interleukin-2-inducible T cell kinase (ITK), which plays a crucial role in T cell and natural killer (NK) cell immune functions. Corvus' lead investigational product, soquelitinib (formerly CPI-818), has shown promise in optimizing T cell differentiation and enhancing immune responses against tumors, as well as in the management of autoimmune diseases.
Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed peripheral T cell lymphoma (PTCL), an aggressive and typically treatment-resistant form of non-Hodgkin’s lymphoma. The company’s focus on ITK inhibition offers a new therapeutic approach, given the lack of FDA-approved treatments for relapsed PTCL. Soquelitinib has demonstrated the ability to prevent T cell exhaustion and promote the generation of cytotoxic killer T cells, critical in cancer therapy.
In addition, Corvus is investigating soquelitinib for other immune-mediated conditions, including atopic dermatitis. The company recently initiated a randomized, double-blind Phase 1 clinical trial to evaluate soquelitinib in patients with moderate to severe atopic dermatitis, aiming to provide an oral treatment alternative to current injectable biologics.
Other promising candidates in Corvus' pipeline include ciforadenant, an adenosine A2A receptor inhibitor that disables tumors' immune evasion mechanisms, and mupadolimab, a monoclonal antibody targeting CD73. These candidates are being studied for their efficacy in combination therapies for various cancers, including head and neck cancers and non-small cell lung cancer.
Financially, Corvus maintains a strong position, having raised significant capital through direct offerings to support its clinical trials and operational needs. With cash reserves projected to fund operations into late 2025, Corvus is well-positioned to achieve substantial milestones in its clinical programs. The company continues to foster critical partnerships, including collaborations with Angel Pharmaceuticals for the Chinese market.
Latest news highlights Corvus' progress in clinical trials and strategic financing moves, underscoring its commitment to bringing innovative immunotherapies to patients in need. For more information, visit the Corvus Pharmaceuticals website.
Corvus Pharmaceuticals (NASDAQ: CRVS) announced the completion of patient enrollment in a Phase 1 study of CPI-006, an immunotherapy for hospitalized COVID-19 patients. Data presented at the SITC Annual Meeting indicates that CPI-006 enhances polyclonal humoral immunity, with patients showing significant antibody responses to SARS-CoV-2. Following promising results, a pivotal, randomized trial is set to begin in December 2020, with results anticipated by mid-2021. The R&D Symposium on November 12 will further detail these findings and updates on cancer programs.
Corvus Pharmaceuticals (NASDAQ: CRVS) will host a webcast R&D Symposium on November 12, 2020, focusing on its COVID-19 program and cancer updates. The event features key presentations, including an oral presentation of CPI-006 data at the SITC Annual Meeting from November 9-14, 2020. CPI-006 showed promise in stimulating immune response in mild to moderate COVID-19 patients. The symposium will discuss ongoing clinical trials and invite questions from attendees, providing insights into Corvus's innovative approaches in immunotherapy.
Corvus Pharmaceuticals (CRVS) reported a net loss of $9.8 million for Q3 2020, improving from $11.0 million in Q3 2019. Cash reserves decreased to $51.4 million from $78.0 million at year-end 2019. R&D expenses fell to $6.6 million, while G&A expenses rose to $3.2 million. Key developments include upcoming FDA meetings for ciforadenant in renal cell cancer and promising early results for CPI-006 in COVID-19, with plans for a larger trial by year-end. The co-founding of Angel Pharmaceuticals will enhance global pipeline development.
Corvus Pharmaceuticals (NASDAQ: CRVS) is set to present updated data from its Phase 1 study of CPI-006, an immunotherapy for COVID-19, at the 2020 Society for Immunotherapy of Cancer (SITC) Annual Meeting from November 9-14, 2020. A poster on the study will be available during the event, highlighting CPI-006's ability to stimulate anti-SARS-CoV-2 antibody responses.
The company will also host an R&D Symposium webcast on November 12, 2020, showcasing COVID-19 program data and advancements in its cancer portfolio.
Corvus Pharmaceuticals announced a strategic collaboration with Angel Pharmaceuticals, securing a 49.7% equity stake to enhance its oncology pipeline development in China. Angel, a new biopharmaceutical company, aims to address serious diseases and launches with a $41 million financing, valuing it at $106 million. The collaboration allows for the development of three clinical-stage candidates and global BTK inhibitor programs. Clinical trials for these candidates are expected to commence within 12 to 18 months, leveraging a partnership with prominent Chinese investors and a talented local team.
Corvus Pharmaceuticals (CRVS) announced the completion of enrollment for the first three cohorts of its Phase 1 study for CPI-006, a novel immunotherapy targeting COVID-19. The data indicates a dose-response effect with prolonged high titers of SARS-CoV-2 specific antibodies at 56 days in the 1.0 mg/kg cohort. All treated patients showed increased memory B and T cells, and no drug-related safety issues were reported. Final cohort enrollment is underway, and a pivotal study is planned by year-end. Results are expected at the upcoming SITC meeting in November.
Corvus Pharmaceuticals (CRVS) announced new data from its collaboration with Genentech during the ESMO Virtual Congress 2020. The data focuses on ciforadenant combined with atezolizumab for treating non-small cell lung cancer (NSCLC). In a small study, patients showed longer disease control and overall survival compared to chemotherapy. The median overall survival was 11.5 months for the combination group versus 9.4 months for chemotherapy. Safety data indicated fewer adverse events. Corvus aims to advance ciforadenant into pivotal studies for advanced refractory renal cell cancer.
Corvus Pharmaceuticals (NASDAQ: CRVS) announced promising results from its Phase 1 study of CPI-006 as an immunotherapy for COVID-19. Patients in the first two cohorts exhibited significant antibody responses within 7 days, with neutralizing antibody levels rising to >1:200,000 by day 28. All treated patients showed clinical improvement and were discharged without safety issues. The study has enrolled 30 patients, with plans for an FDA meeting to discuss future pivotal studies. CPI-006 aims to activate the immune system potentially offering long-term immunity against SARS-CoV-2.
Corvus Pharmaceuticals (NASDAQ: CRVS) announced its participation in two upcoming investor conferences. The company will present at the HC Wainwright 22nd Annual Investment Conference on September 14, 2020, at 4:00 PM ET, and at the Cantor Virtual Healthcare Conference on September 17, 2020, at 4:40 PM ET. Both presentations will be available via webcast for 90 days on the Corvus website. Corvus is focused on developing innovative therapies for cancer and is currently advancing multiple clinical trials.
Corvus Pharmaceuticals (NASDAQ: CRVS) will present at the 2020 Wedbush PacGrow Healthcare Virtual Conference on August 11 from 2:55-3:25pm ET. A live webcast will be available for 90 days post-event via the Corvus website.
The company is focused on innovative cancer treatments, studying lead candidates CPI-444 and CPI-006 in various clinical trials. Their research also explores CPI-818 for T-cell lymphomas and CPI-006 for COVID-19.
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