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Corvus Pharmaceuticals, Inc. - CRVS STOCK NEWS

Welcome to our dedicated page for Corvus Pharmaceuticals news (Ticker: CRVS), a resource for investors and traders seeking the latest updates and insights on Corvus Pharmaceuticals stock.

Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS) is a pioneering clinical-stage biopharmaceutical company focused on the development of novel immunotherapies to treat a broad spectrum of cancers and immune diseases. The company's core innovation is the selective inhibition of interleukin-2-inducible T cell kinase (ITK), which plays a crucial role in T cell and natural killer (NK) cell immune functions. Corvus' lead investigational product, soquelitinib (formerly CPI-818), has shown promise in optimizing T cell differentiation and enhancing immune responses against tumors, as well as in the management of autoimmune diseases.

Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed peripheral T cell lymphoma (PTCL), an aggressive and typically treatment-resistant form of non-Hodgkin’s lymphoma. The company’s focus on ITK inhibition offers a new therapeutic approach, given the lack of FDA-approved treatments for relapsed PTCL. Soquelitinib has demonstrated the ability to prevent T cell exhaustion and promote the generation of cytotoxic killer T cells, critical in cancer therapy.

In addition, Corvus is investigating soquelitinib for other immune-mediated conditions, including atopic dermatitis. The company recently initiated a randomized, double-blind Phase 1 clinical trial to evaluate soquelitinib in patients with moderate to severe atopic dermatitis, aiming to provide an oral treatment alternative to current injectable biologics.

Other promising candidates in Corvus' pipeline include ciforadenant, an adenosine A2A receptor inhibitor that disables tumors' immune evasion mechanisms, and mupadolimab, a monoclonal antibody targeting CD73. These candidates are being studied for their efficacy in combination therapies for various cancers, including head and neck cancers and non-small cell lung cancer.

Financially, Corvus maintains a strong position, having raised significant capital through direct offerings to support its clinical trials and operational needs. With cash reserves projected to fund operations into late 2025, Corvus is well-positioned to achieve substantial milestones in its clinical programs. The company continues to foster critical partnerships, including collaborations with Angel Pharmaceuticals for the Chinese market.

Latest news highlights Corvus' progress in clinical trials and strategic financing moves, underscoring its commitment to bringing innovative immunotherapies to patients in need. For more information, visit the Corvus Pharmaceuticals website.

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Corvus Pharmaceuticals (NASDAQ: CRVS), a clinical-stage biopharmaceutical company, has announced a conference call and webcast scheduled for August 6, 2024, at 4:30 pm ET (1:30 pm PT). The event will provide a business update and report second quarter 2024 financial results. Interested parties can access the call by dialing 1-800-717-1738 (toll-free domestic) or 1-646-307-1865 (international), or by using a provided link for instant telephone access. A live webcast will be available through the investor relations section of Corvus' website, with a replay accessible for 90 days post-event.

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Corvus Pharmaceuticals (NASDAQ: CRVS) announced the publication of preclinical data in Science Signaling, demonstrating the potential of ITK inhibition with soquelitinib for treating inflammatory diseases. The study, conducted by Cornell University researchers, showed that ITK inhibition induces switching of proinflammatory Th17 cells into anti-inflammatory Treg cells, both in vitro and in vivo.

Key findings include:

  • Dose-dependent inhibition of Th17 cell differentiation and increase in Foxp3+ Treg cells
  • Switched Foxp3+ Treg cells suppress naïve T cell proliferation
  • Significant reduction of Th17 cells in the lung in a mouse model of allergic airway inflammation

This research supports Corvus' view on the broad potential of ITK inhibition for treating autoimmune, allergic, and inflammatory diseases.

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Corvus Pharmaceuticals, a clinical-stage biopharmaceutical company listed on NASDAQ under the ticker CRVS, has announced that it will participate in the Jefferies Global Health Conference in New York from June 5-7, 2024. The company's CEO, Richard A. Miller, and Chief Business Officer, Jeffrey Arcara, will present a corporate overview and conduct one-on-one meetings with investors. The presentation is scheduled for June 5 at 3:00 pm ET and will be webcast live, with the recording available for 90 days on the company's investor relations webpage.

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Corvus Pharmaceuticals, a clinical-stage biopharmaceutical company, reported strong progress in advancing soquelitinib for PTCL and generating early data for atopic dermatitis. Recent financing provided runway for expected clinical readouts in 2024-2025. Positive Phase 1 trial results for ciforadenant in renal cell cancer. Corvus also collaborates with Kidney Cancer Research Consortium and Angel Pharmaceuticals. Financially, Corvus reported cash, cash equivalents, and marketable securities of $22.1 million as of March 31, 2024, with expected full year 2024 net cash used in operating activities between $24-27 million.

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Corvus Pharmaceuticals, Inc. (NASDAQ: CRVS) will provide a business update and report first quarter 2024 financial results on May 6, 2024. The company will host a conference call and webcast at 4:30 pm ET / 1:30 pm PT. Investors can access the call through dial-in numbers or the webcast link. A replay will be available on the company's website.

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Corvus Pharmaceuticals has announced a $30.6 million registered direct offering to raise gross proceeds through the sale of common stock and warrants. The offering includes participation from various healthcare investors and existing investors, with the company's CEO also joining. The offering is expected to close on May 6, 2024.

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Corvus Pharmaceuticals announces the initiation of a Phase 1 clinical trial for soquelitinib in patients with atopic dermatitis, with potential initial clinical data before year-end 2024.
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Corvus Pharmaceuticals, Inc. (CRVS) provides a business update, highlighting progress with soquelitinib in Phase 3 clinical trial for PTCL and Phase 1 trial for atopic dermatitis. Positive interim data from Phase 1/1b trial, Orphan Drug Designation, and FDA alignment for Phase 3 trial are key milestones. The company plans to initiate trials in 2024. Financially, Corvus had $27.1 million in cash as of December 31, 2023, with a net loss of $6.7 million for Q4 2023.
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Corvus Pharmaceuticals, Inc. (CRVS) will host a conference call and webcast on March 19, 2024, to discuss business updates and report financial results for Q4 and full year 2023.
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Corvus Pharmaceuticals, Inc. unveils next-gen ITK inhibitor candidates for precise T cell modulation in immunology indications. Preclinical data for soquelitinib program presented at Keystone Symposia. Next-gen candidates aim to enable more precise inhibition of Th1, Th2, and Th17 cell function. Various disease types targeted with refined chemical structures. Soquelitinib shows activity in six T cell-mediated inflammatory and immune diseases. Potential to treat atopic dermatitis, asthma, psoriasis, rheumatoid arthritis, and more.
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FAQ

What is the current stock price of Corvus Pharmaceuticals (CRVS)?

The current stock price of Corvus Pharmaceuticals (CRVS) is $7.39 as of December 17, 2024.

What is the market cap of Corvus Pharmaceuticals (CRVS)?

The market cap of Corvus Pharmaceuticals (CRVS) is approximately 438.2M.

What is Corvus Pharmaceuticals' lead product candidate?

Corvus Pharmaceuticals' lead product candidate is soquelitinib (formerly CPI-818), an investigational small molecule drug designed to selectively inhibit ITK (interleukin-2-inducible T cell kinase).

What conditions is Corvus Pharmaceuticals targeting with soquelitinib?

Soquelitinib is being developed for the treatment of relapsed peripheral T cell lymphoma (PTCL), atopic dermatitis, and potentially other autoimmune and cancer indications.

What is the significance of ITK inhibition in Corvus Pharmaceuticals' research?

ITK inhibition plays a key role in optimizing T cell differentiation and enhancing immune responses, which can be critical for treating cancers and immune diseases.

What other products are in Corvus Pharmaceuticals' pipeline?

Corvus' pipeline includes ciforadenant (an adenosine A2A receptor inhibitor) and mupadolimab (a monoclonal antibody targeting CD73), both of which are being evaluated in combination therapies for various cancers.

What recent financial developments have supported Corvus Pharmaceuticals' research?

Corvus recently raised approximately $30.6 million through a registered direct offering, bolstering its cash reserves to fund ongoing and upcoming clinical trials.

What is the background of Corvus Pharmaceuticals?

Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company specializing in novel immunotherapies. It was co-founded by Richard A. Miller, M.D., who also serves as its president and CEO.

What partnerships does Corvus Pharmaceuticals have?

Corvus Pharmaceuticals collaborates with Angel Pharmaceuticals to develop and commercialize its leading candidates in China and has invested heavily in top-tier scientific talent and innovative research.

How is Corvus Pharmaceuticals addressing the unmet needs in relapsed PTCL?

Corvus is advancing soquelitinib through a Phase 3 registrational trial for relapsed PTCL, aiming to provide a new therapy for a condition with limited existing treatment options.

How is soquelitinib being evaluated for atopic dermatitis?

A Phase 1 clinical trial for soquelitinib in patients with moderate to severe atopic dermatitis has been initiated to evaluate its safety, tolerability, and efficacy.

What makes mupadolimab unique in Corvus Pharmaceuticals' research?

Mupadolimab is designed to target CD73, stimulating B cells and blocking immunosuppressive adenosine production, enhancing the immune response in cancer treatments.

Corvus Pharmaceuticals, Inc.

Nasdaq:CRVS

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CRVS Stock Data

438.23M
51.52M
4.02%
44.47%
4.68%
Biotechnology
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