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Crinetics Pharmaceuticals, Inc. - CRNX STOCK NEWS

Welcome to our dedicated page for Crinetics Pharmaceuticals news (Ticker: CRNX), a resource for investors and traders seeking the latest updates and insights on Crinetics Pharmaceuticals stock.

Crinetics Pharmaceuticals, Inc. (NASDAQ: CRNX) is a clinical-stage pharmaceutical company dedicated to the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Founded with a mission to create impactful treatments, Crinetics focuses on advancing its innovative pipeline of orally delivered small molecule drugs.

The company's leading product candidate, paltusotine, is an investigational somatostatin receptor type 2 (SST2) agonist, currently in Phase 3 development for acromegaly and Phase 2 for carcinoid syndrome associated with neuroendocrine tumors. Paltusotine promises a convenient, once-daily oral treatment alternative to monthly injections, simplifying patient care and improving quality of life.

Moreover, Crinetics is advancing CRN04894 (atumelnant), a first-in-class oral ACTH antagonist in Phase 2 trials for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease. This promising candidate aims to address significant unmet needs in these patient populations by reducing disease drivers and normalizing hormone levels.

Crinetics' in-house drug discovery efforts have resulted in several ongoing programs targeting conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes, and obesity. The company's robust pipeline highlights its commitment to developing transformative therapies for patients with rare endocrine disorders.

Recent achievements include a successful private placement of $350 million, strengthening their financial position to support ongoing research and development. The company also reported positive topline results from its Phase 2 study of paltusotine for carcinoid syndrome, as well as from its Phase 3 PATHFNDR-2 study for acromegaly, reinforcing the potential of paltusotine in providing both symptom and biochemical control.

With strategic partnerships, including collaborations with top institutional investors and the National Institutes of Health, Crinetics is well-positioned for future growth. The company remains committed to bringing innovative treatments to market and improving the lives of patients worldwide.

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Crinetics Pharmaceuticals, Inc. reported financial results for Q2 2023. The company expects to release topline data from its Phase 3 PATHFNDR-1 study in September 2023, providing insight into paltusotine's potential as an alternative treatment for acromegaly. Enrollment in the Phase 3 PATHFNDR-2 study is complete, with topline results expected in Q1 2024. However, the company has suspended development of its CRN04777 program due to nonclinical profile concerns. Crinetics plans to submit a new drug application for paltusotine in acromegaly in 2024.
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Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) will host a Key Opinion Leader (KOL) webinar featuring presentations by KOLs Beverly MK Biller M.D. and Karen JP Liebert, R.N., BSN, both of Massachusetts General Hospital. They will discuss the current landscape and unmet medical need in acromegaly, as well as the treatment burden associated with standard-of-care injectable somatostatin receptor ligands (SRLs). The Crinetics management team will also discuss its pipeline of internally discovered oral small molecule drug candidates, with a focus on the Phase 3 PATHFNDR-1 study of paltusotine, an investigational, once-daily oral small molecule somatostatin receptor type 2 agonist.
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Crinetics Pharmaceuticals reports financial results for Q1 2023 and provides updates on its clinical programs
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On April 10, 2023, Crinetics Pharmaceuticals (Nasdaq: CRNX) announced the grant of non-qualified stock options to 15 new non-executive employees, totaling 311,700 shares under the 2021 Employment Inducement Incentive Award Plan. These options, aimed at attracting new talent, have an exercise price of $16.02 per share, equivalent to the closing stock price on the grant date. The options will vest over four years, incentivizing continued employment. Crinetics focuses on developing innovative therapeutics for rare endocrine diseases and related tumors, with ongoing clinical trials for its drug candidates, including Paltusotine for acromegaly. The company aims to address significant unmet medical needs in this niche area.

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FAQ

What is the current stock price of Crinetics Pharmaceuticals (CRNX)?

The current stock price of Crinetics Pharmaceuticals (CRNX) is $54.72 as of November 15, 2024.

What is the market cap of Crinetics Pharmaceuticals (CRNX)?

The market cap of Crinetics Pharmaceuticals (CRNX) is approximately 5.1B.

What does Crinetics Pharmaceuticals do?

Crinetics Pharmaceuticals specializes in the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors.

What are Crinetics' main product candidates?

Crinetics' main product candidates are paltusotine, in development for acromegaly and carcinoid syndrome, and CRN04894 (atumelnant), in development for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease.

What is paltusotine?

Paltusotine is an investigational, oral somatostatin receptor type 2 (SST2) agonist aimed at treating acromegaly and carcinoid syndrome.

What is CRN04894 (atumelnant)?

CRN04894, also known as atumelnant, is an investigational, first-in-class, oral ACTH antagonist in development for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease.

What recent achievements has Crinetics announced?

Crinetics recently secured $350 million through a private placement and reported positive topline results from its Phase 2 carcinoid syndrome study and Phase 3 PATHFNDR-2 study for acromegaly.

Who are some of Crinetics' key partners?

Crinetics collaborates with top institutional investors, such as Adage Capital Partners and Janus Henderson Investors, and has ongoing studies with the National Institutes of Health.

How does Crinetics aim to improve patient care?

Crinetics aims to improve patient care by developing orally delivered small molecule drugs that offer convenient alternatives to current treatments, potentially improving quality of life for patients with rare endocrine diseases.

What are some conditions Crinetics is targeting with its discovery programs?

Crinetics targets conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes, and obesity through its discovery programs.

How is Crinetics funded for its research and development?

Crinetics is funded through private placements and strategic partnerships with institutional investors, enabling continued research and development of its clinical-stage product candidates.

What is Crinetics' strategy for future growth?

Crinetics' strategy for future growth includes advancing its pipeline of novel therapeutics, collaborating with key partners, and bringing innovative treatments to market to address significant unmet needs in endocrine diseases.

Crinetics Pharmaceuticals, Inc.

Nasdaq:CRNX

CRNX Rankings

CRNX Stock Data

5.06B
92.74M
1.87%
98.21%
7.32%
Biotechnology
Pharmaceutical Preparations
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United States of America
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