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Crinetics Pharmaceuticals, Inc. - CRNX STOCK NEWS

Welcome to our dedicated page for Crinetics Pharmaceuticals news (Ticker: CRNX), a resource for investors and traders seeking the latest updates and insights on Crinetics Pharmaceuticals stock.

Crinetics Pharmaceuticals, Inc. (NASDAQ: CRNX) is a clinical-stage pharmaceutical company dedicated to the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Founded with a mission to create impactful treatments, Crinetics focuses on advancing its innovative pipeline of orally delivered small molecule drugs.

The company's leading product candidate, paltusotine, is an investigational somatostatin receptor type 2 (SST2) agonist, currently in Phase 3 development for acromegaly and Phase 2 for carcinoid syndrome associated with neuroendocrine tumors. Paltusotine promises a convenient, once-daily oral treatment alternative to monthly injections, simplifying patient care and improving quality of life.

Moreover, Crinetics is advancing CRN04894 (atumelnant), a first-in-class oral ACTH antagonist in Phase 2 trials for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease. This promising candidate aims to address significant unmet needs in these patient populations by reducing disease drivers and normalizing hormone levels.

Crinetics' in-house drug discovery efforts have resulted in several ongoing programs targeting conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes, and obesity. The company's robust pipeline highlights its commitment to developing transformative therapies for patients with rare endocrine disorders.

Recent achievements include a successful private placement of $350 million, strengthening their financial position to support ongoing research and development. The company also reported positive topline results from its Phase 2 study of paltusotine for carcinoid syndrome, as well as from its Phase 3 PATHFNDR-2 study for acromegaly, reinforcing the potential of paltusotine in providing both symptom and biochemical control.

With strategic partnerships, including collaborations with top institutional investors and the National Institutes of Health, Crinetics is well-positioned for future growth. The company remains committed to bringing innovative treatments to market and improving the lives of patients worldwide.

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Crinetics Pharmaceuticals, Inc. (CRNX) announces positive topline results from the PATHFNDR-2 Phase 3 study on paltusotine for acromegaly treatment. 56% of participants achieved IGF-1 ≤1.0 xULN vs. 5% on placebo, meeting primary and secondary endpoints. No serious adverse events reported, supporting planned NDA submission in 2H 2024.
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Crinetics Pharmaceuticals, Inc. (CRNX) announced positive topline results from its Phase 2 study of paltusotine for carcinoid syndrome. The study showed rapid and sustained reductions in flushing episodes and bowel movements, with overall positive patient outcomes. The company plans to move towards Phase 3 trials by the end of the year.
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Crinetics Pharmaceuticals, Inc. (CRNX) granted non-qualified stock options to five new non-executive employees under the 2021 Inducement Plan. The options have an exercise price of $42.29 per share and will vest over four years.
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Crinetics Pharmaceuticals, Inc. (CRNX) reported financial results, achieving milestones in 2023 with positive data from Phase 3 studies on paltusotine for acromegaly and carcinoid syndrome. Pending results from PATHFNDR-2 study, NDA submission for acromegaly is expected in 2H 2024. The company announced a $350 million private placement financing to support growth and expects transformational years in 2024 and 2025.
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Crinetics Pharmaceuticals, Inc. (CRNX) announced a private placement of 8,333,334 shares of its common stock at $42.00 per share, expecting to raise around $350 million. The private placement targets institutional and accredited healthcare specialist investors.
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Crinetics Pharmaceuticals, Inc. (CRNX) will announce its Q4 and full-year 2023 financial results on February 28, 2024. The company will host a conference call and webcast to discuss the results and provide a business update.
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Crinetics Pharmaceuticals, Inc. (CRNX) granted non-qualified stock options to nine new non-executive employees. The options, with an exercise price of $39.46 per share, total 73,000 shares and will vest over four years. This grant is in line with the 2021 Inducement Plan to attract new talent to the company.
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Crinetics Pharmaceuticals, Inc. (CRNX) granted non-qualified stock options to 8 new non-executive employees under the 2021 Employment Inducement Incentive Award Plan. The options have an exercise price of $37.60 per share and will vest over four years.
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Crinetics Pharmaceuticals, Inc. (CRNX) to Present at 42nd Annual J.P. Morgan Healthcare Conference
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Radionetics Oncology, Inc. (RADN) completes $52.5 million Series A financing led by Frazier Life Sciences, 5AM Ventures, and DCVC Bio, bringing total raised to date to $82.5 million. Paul Grayson joins as CEO, bringing expertise in business strategy, oncology, and G-protein coupled receptor biology. Eric Shiozaki, Ph.D., Partner at DCVC Bio, appointed to the board of directors.
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FAQ

What is the current stock price of Crinetics Pharmaceuticals (CRNX)?

The current stock price of Crinetics Pharmaceuticals (CRNX) is $53.6 as of December 20, 2024.

What is the market cap of Crinetics Pharmaceuticals (CRNX)?

The market cap of Crinetics Pharmaceuticals (CRNX) is approximately 4.9B.

What does Crinetics Pharmaceuticals do?

Crinetics Pharmaceuticals specializes in the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors.

What are Crinetics' main product candidates?

Crinetics' main product candidates are paltusotine, in development for acromegaly and carcinoid syndrome, and CRN04894 (atumelnant), in development for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease.

What is paltusotine?

Paltusotine is an investigational, oral somatostatin receptor type 2 (SST2) agonist aimed at treating acromegaly and carcinoid syndrome.

What is CRN04894 (atumelnant)?

CRN04894, also known as atumelnant, is an investigational, first-in-class, oral ACTH antagonist in development for congenital adrenal hyperplasia and ACTH-dependent Cushing's disease.

What recent achievements has Crinetics announced?

Crinetics recently secured $350 million through a private placement and reported positive topline results from its Phase 2 carcinoid syndrome study and Phase 3 PATHFNDR-2 study for acromegaly.

Who are some of Crinetics' key partners?

Crinetics collaborates with top institutional investors, such as Adage Capital Partners and Janus Henderson Investors, and has ongoing studies with the National Institutes of Health.

How does Crinetics aim to improve patient care?

Crinetics aims to improve patient care by developing orally delivered small molecule drugs that offer convenient alternatives to current treatments, potentially improving quality of life for patients with rare endocrine diseases.

What are some conditions Crinetics is targeting with its discovery programs?

Crinetics targets conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes, and obesity through its discovery programs.

How is Crinetics funded for its research and development?

Crinetics is funded through private placements and strategic partnerships with institutional investors, enabling continued research and development of its clinical-stage product candidates.

What is Crinetics' strategy for future growth?

Crinetics' strategy for future growth includes advancing its pipeline of novel therapeutics, collaborating with key partners, and bringing innovative treatments to market to address significant unmet needs in endocrine diseases.

Crinetics Pharmaceuticals, Inc.

Nasdaq:CRNX

CRNX Rankings

CRNX Stock Data

4.89B
89.30M
1.8%
94.7%
7.01%
Biotechnology
Pharmaceutical Preparations
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United States of America
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