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Charles Riv Labs Intl Inc - CRL STOCK NEWS

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Overview of Charles River Laboratories International, Inc. (CRL)

Charles River Laboratories International, Inc. (CRL) is a globally recognized contract research organization (CRO) that provides essential services to pharmaceutical, biotechnology, academic, and government clients. The company specializes in supporting the discovery, development, and safe manufacturing of new therapies, playing a pivotal role in the life sciences ecosystem. With a comprehensive portfolio of products and services, CRL helps its clients accelerate research timelines and optimize the drug development process, making it a critical partner in the creation of innovative treatments for patients worldwide.

Core Business Areas

Charles River Laboratories operates across several key business segments, each tailored to meet the diverse needs of its clients:

  • Discovery and Early-Stage Development: CRL provides services that span the early phases of drug discovery, including target identification, validation, and preclinical testing. These services are designed to help clients identify viable drug candidates efficiently.
  • Safety Assessment: The company offers toxicology and safety evaluation services to ensure that new therapies meet regulatory requirements and are safe for further development.
  • Research Models and Services: CRL supplies high-quality research models, including genetically engineered models, as well as associated services to support in vivo research.
  • Manufacturing Support: The company provides services such as microbial detection, biopharmaceutical testing, and cell and gene therapy manufacturing support, which are critical for ensuring the quality and safety of therapeutic products.

Market Position and Industry Context

Operating at the intersection of biotechnology, pharmaceuticals, and academic research, Charles River Laboratories serves a growing market driven by the increasing complexity and cost of drug development. The rise of precision medicine, biologics, and cell and gene therapies has further expanded the demand for specialized CRO services. CRL differentiates itself through its end-to-end service offerings, global infrastructure, and expertise in early-stage research, making it a preferred partner for organizations looking to outsource R&D activities. Its ability to integrate discovery, safety assessment, and manufacturing support under one roof provides a seamless experience for clients, reducing time-to-market for new therapies.

Competitive Landscape

Charles River Laboratories faces competition from other CROs such as Labcorp Drug Development, ICON plc, and PPD. However, its focus on early-stage research, coupled with a broad service portfolio and a strong reputation for scientific expertise, sets it apart. The company's investments in technology, innovation, and global infrastructure further strengthen its competitive position, enabling it to address the evolving needs of the life sciences industry.

Significance in the Life Sciences Ecosystem

As a trusted partner to pharmaceutical and biotechnology companies, Charles River Laboratories plays a crucial role in advancing medical innovation. By providing specialized expertise and resources, the company helps its clients navigate the complexities of drug development, ensuring that new therapies reach patients more efficiently. This makes CRL an indispensable player in the global effort to improve healthcare outcomes.

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Charles River Laboratories International, Inc. (NYSE: CRL) is set to release its fourth-quarter and full-year 2023 financial results and provide 2024 guidance on February 14th. A conference call will be held at 8:30 a.m. ET on the same day to discuss the information. Investors can listen to a live webcast through the Company's website and access a replay afterward.
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Charles River Laboratories International, Inc. (NYSE: CRL) has launched off-the-shelf Rep/Cap plasmid offering to streamline adeno-associated virus (AAV)-based gene therapy programs, reducing manufacturing effort by up to 66%. The ready-to-use plasmid products are produced and released according to batch production records, with CMC guidance and a Certificate of Analysis (COA) to support Investigational New Drug (IND) and Clinical Trial Application (CTA) filing. The launch will take place at Advanced Therapies Week, January 16-19, at the Miami Beach Convention Center.
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Charles River Laboratories International, Inc. (NYSE: CRL) will present at the 42nd Annual J.P. Morgan Healthcare Conference on January 9th, discussing strategic focus, business developments, and recent trends. A live webcast and replay will be available on the Investor Relations section of the Charles River website at ir.criver.com.
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Charles River Laboratories International, Inc. (NYSE: CRL) has achieved a significant milestone in their collaboration with Vertex to manufacture CASGEVY™, the world’s first gene-edited therapy targeting severe sickle cell disease. The Memphis facility received regulatory approval from the FDA and HPRA to commercially manufacture an allogeneic cell therapy drug product. This approval enables Charles River to work with Vertex to help bring this groundbreaking treatment to patients suffering from severe sickle cell disease.
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Charles River Laboratories International, Inc. (NYSE: CRL) has entered into an agreement with CELLphenomics, a biotechnology company using 3D hydrogel technology to advance the understanding of the tumor microenvironment and predict therapeutic efficacy. CELLphenomics’ proprietary 3D tumor model platform, PD3D®, will expand Charles River’s 3D in vitro testing services to optimize oncological approaches for clients. The platform provides reliable, predictive preclinical PD3D models that recapitulate the biological properties of the donor tissue, including key histopathological features and genomic makeup. CELLphenomics’ continuously growing biobank comprises more than 500 complex in vitro models from over 20 tumor entities, offering the world’s largest collection of complex in vitro models of rare and ultra-rare tumors. Leveraging CELLphenomics technology, Charles River will have a novel in vitro option for identifying therapeutics for rare and ultra-rare disease types, with full access to Charles River’s impressive biobank and data.
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Charles River Laboratories International, Inc. (CRL) partners with Genetic Cures for Kids Inc (GC4K) to produce plasmid DNA for early phase trials of gene therapy for Hereditary Spastic Paraplegia Type 56 (SPG56), a rare neurodegenerative disease. SPG56 affects motor and cognitive functions and currently has no treatment. GC4K aims to develop a gene therapy not only for SPG56 but also as a model for treating other rare genetic diseases. Charles River's eXpDNA™ platform and HQ Plasmid Manufacturing Center of Excellence will support GC4K's mission by providing high-quality plasmid DNA production services.
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Charles River Laboratories International, Inc. (CRL) will present at the 6th Annual Evercore ISI HealthCONx Conference on November 29th, discussing strategic focus, business developments, and recent trends. The presentation will be available via live webcast and replay on the Investor Relations section of their website.
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Charles River Laboratories International, Inc. (NYSE: CRL) expands its CliniPrime™ suite with the launch of CliniPrime Cryopreserved Leukopaks for gene-modified cell therapy development and manufacturing. Cryopreserved leukopaks play a critical role in research and development, maximizing cellular viability, consistency, and long-term availability. The new offering aims to meet the growing industry need for reliable and consistent sources of cellular starting material, supporting both clinical trial development and commercialization.
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Charles River Laboratories International, Inc. (NYSE: CRL) and Aitia announce a strategic partnership focused on co-developing patient-derived xenograft (PDX) Digital Twins for in vivo oncology research. Aitia will deploy Charles River's AI-powered drug solution platform, Logica, to optimize the discovery and early development of therapeutic programs for neurodegenerative disease and oncology. The agreement also includes the development of a PDX Digital Twin to predict the best tumor models for in vivo oncology research. Charles River has made an equity investment in Aitia as part of the partnership.
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Charles River Laboratories International, Inc. (NYSE: CRL) to Present 19 Scientific Posters at Neuroscience 2023
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FAQ

What is the current stock price of Charles Riv Labs Intl (CRL)?

The current stock price of Charles Riv Labs Intl (CRL) is $163.5 as of March 3, 2025.

What is the market cap of Charles Riv Labs Intl (CRL)?

The market cap of Charles Riv Labs Intl (CRL) is approximately 9.7B.

What does Charles River Laboratories International, Inc. do?

Charles River Laboratories is a contract research organization (CRO) that provides services for drug discovery, early-stage development, and manufacturing support to pharmaceutical, biotechnology, academic, and government clients.

What industries does Charles River Laboratories serve?

The company serves the pharmaceutical, biotechnology, academic, and government sectors, primarily focusing on the life sciences industry.

How does Charles River Laboratories generate revenue?

CRL generates revenue by offering a range of services, including discovery and early-stage development support, safety assessment, research models, and manufacturing support for therapeutic products.

What sets Charles River Laboratories apart from competitors?

CRL differentiates itself through its comprehensive service offerings, expertise in early-stage research, and global infrastructure, providing clients with an integrated approach to drug development.

What role does Charles River Laboratories play in drug development?

The company supports its clients by providing essential services and expertise that accelerate research timelines, ensure regulatory compliance, and optimize the development of new therapies.

Who are the competitors of Charles River Laboratories?

Key competitors include Labcorp Drug Development, ICON plc, and PPD, among others in the contract research organization (CRO) space.

What are Charles River Laboratories' core business segments?

The company's core segments include discovery and early-stage development, safety assessment, research models and services, and manufacturing support.

Why is outsourcing to CROs like Charles River Laboratories important?

Outsourcing to CROs helps pharmaceutical and biotechnology companies reduce costs, access specialized expertise, and navigate the complexities of drug development more efficiently.
Charles Riv Labs Intl Inc

NYSE:CRL

CRL Rankings

CRL Stock Data

9.72B
50.39M
1.36%
102.22%
4.22%
Diagnostics & Research
Services-commercial Physical & Biological Research
Link
United States
WILMINGTON