Corbus Pharmaceuticals to Present Latest Pre-Clinical Data on its Anti-aVb8 Monoclonal Antibody (CRB-601) at the 2023 SITC Annual Meeting
- CRB-601 shows potential to enhance immune checkpoint inhibitors. IND submission expected in Q4 2023.
- None.
Poster Details
Abstract Number: | 1388 |
Title: | CRB-601, an integrin αvβ8 blocking antibody entering Phase I: pre-clinical and translational biomarkers for indication selection. |
Authors: | Vaishali Shinde, Daqing Wang, Danish Memon, Maneesh Singh, James Rindone, Rodney Carter, B.S, Naomi Muse, MBA, Ian Hodgson, PhD, Andrew Kolodziej and Rachael Brake. |
Session Date: | Saturday November 4 |
Presentation Time: | 9:00am to 8:30pm PT |
CRB-601 is a potent and selective integrin αvβ8 blocking monoclonal antibody that can overcome tumor immune exclusion and enhance the activity of immune checkpoint inhibitors in vivo. The IND submission for CRB-601 is anticipated in Q4 2023, and the Company expects to enroll the first patient in its Phase 1 study in the first half of 2024.
The CRB-601 abstract will be available on the SITC website as of Oct. 31, 2023, and the poster will be made available on the Company website following the presenation.
About Corbus
Corbus Pharmaceuticals Holdings, Inc. (the "Company" or "Corbus") is a precision oncology company committed to helping people defeat serious illness by bringing innovative scientific approaches to well understood biological pathways. Corbus' internal development pipeline includes CRB-701, a next generation antibody drug conjugate (ADC) that targets the expression of Nectin-4 on cancer cells to release a cytotoxic payload and CRB-601, an anti-integrin monoclonal antibody which blocks the activation of TGFβ expressed on cancer cells. Corbus is headquartered in
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INVESTOR CONTACT:
Sean Moran
Chief Financial Officer
Corbus Pharmaceuticals
smoran@corbuspharma.com
Bruce Mackle Managing Director
LifeSci Advisors, LLC
bmackle@lifesciadvisors.com
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SOURCE Corbus Pharmaceuticals
