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Cogent Biosciences to Present Preclinical Data on Bezuclastinib at AACR-NCI-EORTC Conference

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Cogent Biosciences (Nasdaq: COGT) will present preclinical data on bezuclastinib at the AACR-NCI-EORTC Virtual International Conference from October 7-10, 2021. The poster titled 'Preclinical data identifies bezuclastinib as a differentiated KIT inhibitor with unique selectivity to KIT D816V' will be available on their website shortly after 9:00 am ET on October 7.

Bezuclastinib targets the KIT D816V mutation related to systemic mastocytosis and various gastrointestinal stromal tumors. This research aims to enhance treatment options for patients with genetically driven diseases.

Positive
  • Presentation of preclinical data at a significant cancer therapeutics conference, which can enhance visibility and credibility.
  • Bezuclastinib shows selective inhibition of KIT D816V, a mutation associated with serious diseases, potentially leading to novel treatment pathways.
Negative
  • None.

CAMBRIDGE, Mass. and BOULDER, Colo., Oct. 1, 2021 /PRNewswire/ -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined diseases, today announced that the Company will present preclinical data on bezuclastinib at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics held October 7-10, 2021.

Poster Presentation Details for Bezuclastinib:
Title: Preclinical data identifies bezuclastinib as a differentiated KIT inhibitor with unique selectivity to KIT D816V and minimal evidence of brain penetration
Virtual Poster Number: P257
Date/Time: All poster presentations are made available by the conference at the opening of the meeting on October 7, 2021, at 9:00 am ET.

The presentation will be available on October 7, 2021 shortly after 9:00 am ET on the Cogent Biosciences website at https://investors.cogentbio.com/events.

About Cogent Biosciences, Inc. 

Cogent Biosciences is a biotechnology company focused on developing precision therapies for genetically defined diseases. The most advanced clinical program, bezuclastinib, is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis, a serious disease caused by unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. In addition to bezuclastinib, the newly formed Cogent Research team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases. Cogent Biosciences is based in Cambridge, MA and Boulder, CO. Visit our website for more information at www.cogentbio.com. Follow Cogent Biosciences on social media: Twitter and LinkedIn. Information that may be important to investors will be routinely posted on our website and Twitter.

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/cogent-biosciences-to-present-preclinical-data-on-bezuclastinib-at-aacr-nci-eortc-conference-301389367.html

SOURCE Cogent Biosciences, Inc.

FAQ

What is the objective of the bezuclastinib presentation at the AACR-NCI-EORTC Conference?

The presentation aims to share preclinical data highlighting bezuclastinib's selectivity for the KIT D816V mutation.

When will Cogent Biosciences present data on bezuclastinib?

The presentation will be available on October 7, 2021, starting at 9:00 am ET.

What is bezuclastinib used for?

Bezuclastinib is a selective tyrosine kinase inhibitor designed to target the KIT D816V mutation, which is linked to systemic mastocytosis and gastrointestinal stromal tumors.

Where can I find the bezuclastinib presentation?

The presentation will be available on the Cogent Biosciences website shortly after it is released at the conference.

What are the implications of the bezuclastinib data for investors?

Positive data on bezuclastinib's efficacy could attract investor interest and enhance Cogent Biosciences' market position.

Cogent Biosciences, Inc.

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