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Cogent Biosciences Announces Bezuclastinib Presentations at the 64th Annual American Society of Hematology (ASH) Meeting

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Cogent Biosciences (Nasdaq: COGT) will present findings on bezuclastinib at the 64th Annual Meeting of the American Society of Hematology (ASH) from December 10-13, 2022, in New Orleans.

An oral presentation will cover the preliminary safety and efficacy from a Phase 2 study in adults with advanced systemic mastocytosis, scheduled for December 11 at 4:45 PM CST. Additionally, a poster presentation on a Phase 2 study for nonadvanced systemic mastocytosis will occur the same day.

A virtual investor event is planned for December 12, 2022, with further details to follow.

Positive
  • Presentation of Phase 2 study results for bezuclastinib indicates potential for marketable therapies.
  • Engagement with investors through a scheduled virtual event may enhance shareholder confidence.
Negative
  • None.

Company to Host Virtual Investor Event on Monday, December 12

WALTHAM, Mass. and BOULDER, Colo., Nov. 03, 2022 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined diseases, today announced upcoming presentations for bezuclastinib at the 64th Annual Meeting of the American Society of Hematology (ASH) being held in New Orleans, LA from December 10-13, 2022. The company will also host a virtual investor event on December 12 that will be accessible via conference call and webcast, with full details to be made available closer to the date.

Oral presentation details:

Preliminary Safety and Efficacy from Apex, a Phase 2 Study of Bezuclastinib (CGT9486), a Novel, Highly Selective, Potent KIT D816V Tyrosine Kinase Inhibitor, in Adults with Advanced Systemic Mastocytosis (AdvSM)
Presenter: Daniel DeAngelo, M.D., Ph.D., Chief of the Division of Leukemia at the Dana-Farber Cancer Institute
Presentation Date and Time: Sunday, December 11, 2022 at 4:45 PM CST
Session Name: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Towards Personalized Medicine in Myeloproliferative Neoplasms and Mastocytosis: New and Repurposed Drugs for Unmet Clinical Needs
Publication Number: 626
Location: Ernest N. Morial Convention Center, 217-219

Trials-in-session poster details:

Summit: A 3-Part, Phase 2 Study of Bezuclastinib (CGT9486), an Oral, Selective, and Potent KIT D816V Inhibitor, in Adult Patients with Nonadvanced Systemic Mastocytosis (NonAdvSM)
Session Name: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster II
Session Date and Time: Sunday, December 11, 2022 from 6:00 PM - 8:00 PM
Publication Number: 3041
Location: Ernest N. Morial Convention Center, Hall D

About Cogent Biosciences, Inc.
Cogent Biosciences is a biotechnology company focused on developing precision therapies for genetically defined diseases. The most advanced clinical program, bezuclastinib, is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis, a serious disease caused by unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. In addition to bezuclastinib, the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases initially targeting FGFR2 and ErbB2. Cogent Biosciences is based in Waltham, MA and Boulder, CO.

Contact:

Christi Waarich
Senior Director, Investor Relations
christi.waarich@cogentbio.com
617-830-1653


FAQ

What is the date and time of Cogent Biosciences' investor event?

The investor event is scheduled for December 12, 2022.

Where will Cogent Biosciences present their findings on bezuclastinib?

Findings will be presented at the 64th Annual Meeting of the American Society of Hematology (ASH) in New Orleans.

What is bezuclastinib being studied for?

Bezuclastinib is being studied for its safety and efficacy in treating advanced systemic mastocytosis.

When is the oral presentation about bezuclastinib scheduled?

The oral presentation is scheduled for December 11, 2022, at 4:45 PM CST.

What type of drug is bezuclastinib?

Bezuclastinib is a selective tyrosine kinase inhibitor targeted at the KIT D816V mutation.

Cogent Biosciences, Inc.

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